Tag: mutation

Questions Related to mutation

DNA fingerprinting is done for ___________________.

  1. Crime investigation

  2. Detection of Hair colour

  3. Gender of the offspring

  4. All of the above


Correct Option: A
Explanation:

DNA profiling or fingerprinting is used in, parentage testing and criminal investigation, to identify a person or to place a person at a crime scene, techniques which are now employed globally in forensic science to facilitate police detective work and help clarify paternity and immigration disputes. Therefore, the correct answer is option A.

Science connected with identification in criminal activities and law is

  1. Medical transcription

  2. Pathology

  3. Forensic science

  4. Computational biology


Correct Option: C
Explanation:

Forensic science is the application of science to the law. In criminal cases, forensic scientists are often involved in the search for an examination of physical traces which might be useful for establishing or excluding an association between someone suspected of committing a crime and the scene of the crime or victim. 

So, the correct option is 'Forensic science'.

The technique used in correct identification of individuals and relations is

  1. Forensic science

  2. Human reproductive biology

  3. Microbiology

  4. DNA fingerprinting


Correct Option: D
Explanation:

DNA fingerprinting is a method used to identify an individual from a sample of DNA by looking at unique patterns in their DNA. DNA is present in blood, hair, semen and various other body cells which can be used to isolate DNA for the process of DNA fingerprinting.

Also, DNA pattern shows the similarity between related especially parents and siblings. Hence, it can be used to establish relations.
So, the correct option is 'DNA fingerprinting'.

The PCR technique was invented by

  1. Karry Mullis

  2. Cohen

  3. Boyer

  4. Sanger


Correct Option: A

Best method to determine paternity is

  1. Protein analysis

  2. Chromosome counting

  3. Gene counting

  4. DNA finger printing


Correct Option: D
Explanation:

About 3% or so of the human genome has highly repetitive sequences termed as simple-sequence DNA or satellite DNA that are repeated in multiples per cell and generate tandem repeats. This DNA polymorphism is revealed during DNA finger printing in the identification of paternity since it is very remote possibility to have two individuals same repeats of satellite DNA throughout the genome except they share a biological relationship. This is because a child gets half DNA from father and half from the mother. Restriction enzymes of genome produce the restriction fragments length polymorphisms, or RFLPs depending on the location of restriction sites which are then sorted by gel electrophoresis followed by southern blotting. The blots of parental and child genome are compared for sequence homology using radioactive probes; option D is correct. 

Protein analysis studies protein structure and function using sequence comparisons, structural and functional assumptions which are useful in the detection of expression of newly introduced genes or in the detection of phylogenetic relationship; two individual do not necessarily express protein polymorphism which makes option A incorrect. 
As we know that all human have 23 pairs of chromosomes which store around 20,000-25,000 genes; chromosome counting and gene counting does not provide any polymorphism to identify paternity which makes options B and C incorrect. Therefore, the correct answer is option D.

Genetic counsellors can identify heterozygous individuals by

  1. Height of individuals

  2. Colour of individuals

  3. Screening procedures

  4. All of these


Correct Option: C
Explanation:
Genetic counselling is about giving information and advice about the, risks of genetic diseases and their outcomes. Genetic screening is a part of genetic counselling which includes prenatal diagnosis, carrier diagnosis and predictive diagnosis.
Genetic counsellors use screening procedure, where sample of blood, hair follicle etc is processed to extract DNA, the DNA is profiled and specific areas  are identified
So, the correct answer is C 'Screening procedures'


A nutritionally wild type organism which does not require additional biochemicals is

  1. Prototroph

  2. Auxotroph

  3. Phenotype

  4. Autotroph


Correct Option: A

Which one is correctly matched?

  1. AUG, ACG Start or methionine

  2. UUA, UCA Leucine

  3. GUU-Alanine

  4. UAG, UGA-Stop


Correct Option: D

DNA finger printing is useful in

  1. Study of polymorphism

  2. Forensic chemical analysis

  3. Analysis of identity and relationship

  4. All the above


Correct Option: D

A - The DNA finger print is the same for every cell, tissue and organ of a person.
R - DNA fingerprint is used for treatment of inherited disorders like Huntigton's disease, Alzheimer's and Sickle cell anemia.

  1. A and R both are correct. R is explanation of A

  2. A and R both are correct but R is not explanation of A

  3. A is correct and R is wrong

  4. A is wrong and R is correct


Correct Option: A
Explanation:

DNA fingerprint is the unique DNA pattern of each individual. It is the same for every cell, tissue and organ of an individual. DNA fingerprinting is a method used to identify an individual on the basis of unique patterns of its DNA. It is used in the diagnosis of inherited disorders like cystic fibrosis, Alzheimer's disease, Huntington's disease, Sickle cell anemia.

Thus, the correct answer is C.