0

Story of dolly, the clone - class-X

Description: story of dolly, the clone
Number of Questions: 19
Created by:
Tags: genetics reproduction in animals mutation biology cell biology and biotechnology
Attempted 0/19 Correct 0 Score 0

First successful animal clone was

  1. Dolly goat

  2. Dolly sheep

  3. Molly goat

  4. Molly sheep


Correct Option: B
Explanation:

The first successful animal clone was Dolly sheep on 5$^{th}$July 1996. It was born as a resultant of three mother one provided the egg, another the DNA, and a third carried the cloned embryo. The used for the production of Dolly is somatic cell nuclear transfer, where the cell nucleus from an adult cell is transferred into an unfertilized oocyte whose nucleus has been removed by the process of irradiation. The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother.

So, the correct answer is option B.

Dolly is the name of well known ___________.

  1. Cloned sheep

  2. Vector

  3. Gene

  4. Virus


Correct Option: A

Which of the following organism was the cytoplasmic donor of Dolly?

  1. Scottish black face sheep

  2. Finn Dorset sheep

  3. Bonnie

  4. Sally


Correct Option: A
Explanation:

Scientists used a Scottish blackface ewe as the cytoplasmic donor (oocyte was used) in the cloning of Dolly sheep. 

So, the correct answer is option A.

Which organism was the nuclear donor for Dolly?

  1. Finn Dorset

  2. Scottish black face

  3. Sally

  4. Rosette


Correct Option: A
Explanation:
Dolly was a female domestic sheep, and the first mammal cloned from an adult somatic cell, using the process of nuclear transfer. It is a transgenic animal.1 Finn Dorset and 2 Scottish blackface ewe were the three parents involved in cloning of Dolly sheep. Finn Dorset was the nuclear donor, it's udder cell's nucleus was used for the purpose and the Scottish black face ewe was the cytoplasmic donor whose egg was used in the cloning of Dolly sheep. Another Scottish black face ewe was a surrogate to the zygote.
So, the correct option is 'Finn Desert'.

How many parents were involved in cloning and production of Dolly?

  1. 2

  2. 1

  3. 3

  4. 4


Correct Option: C
Explanation:

Dolly was a female domestic sheep, and the first mammal cloned from an adult somatic cell, using the process of nuclear transfer. It is a transgenic animal.1 Finn Dorset and 2 Scottish blackface ewe were the three parents involved in cloning of Dolly sheep.

So, the correct option is '3'.

First transgenic sheep were carrying 

  1. genes for $\beta$- lactoglobulin

  2. Genes for Antihemophilic IX

  3. Genes for Thyroxine

  4. More than one correct answer


Correct Option: B
Explanation:

Dolly was a female domestic sheep, and the first mammal cloned from an adult somatic cell, using the process of nuclear transfer. It carries the gene for antihemophilic IX.

So, the correct option is ‘Genes for Antihemophilic IX’.

'Nif' gene for nitrogen fixation in cereal crops like wheat, jowar etc., is introduced by cloning.

  1. Rhizobium meliloti

  2. Bacillus thuringiensis

  3. Rhizopus stolonifer

  4. Agrobacterium tumefaciens


Correct Option: A

First cloned animal was

  1. Dolly sheep

  2. Polly sheep

  3. Molly sheep

  4. Dog


Correct Option: A
Explanation:

Dolly sheep was born on July 5, 1996, through the technique of somatic cell nuclear transfer. It includes the transfer of cell nucleus from an adult cell into an unfertilized, enucleated oocyte (developing egg cell). Electric shock is given to the hybrid cell to stimulate it to divide and the resulting blastocyst is implanted in a surrogate mother. Dolly was the first clone produced from a cell of an adult mammal. Polly and Molly's sheep have also cloned animals produced by somatic cell nuclear transfer but they were cloned after Dolly (in 1997). 

Which of the following was the first successful animal clone? 

  1. Dolly goat

  2. Dolly sheep

  3. Molly goat

  4. Molly sheep


Correct Option: B
Explanation:

Dolly (5 July 1996 – 14 February 2003) was a female domestic sheep and the first animal produced by the cloning from an adult somatic cell by using the process of nuclear transfer. Hence, option B is the correct answer.

Dolly was given birth by ________ 

  1. Finn dorset sheep

  2. Scottish blackface ewe

  3. Polled Dorset sheep

  4. None of these


Correct Option: B
Explanation:

Dolly was given birth by scottish blackface ewe and finn dorset sheep is the one whose nucleus was clonned.

The nucleus for cloning of dolly was taken from ________

  1. Finn dorset sheep

  2. Scottish black face ewe

  3. Both A and B

  4. None of these


Correct Option: A
Explanation:

The correct answer is oil. finn dorsett is sheep from which the nucleus was taken for cloning of dolly, whereas scottish black face ewe was used for implanticen of egq containing nucleus of finn dorseet sheep.

The first mammal clone dolly was created by

  1. Ian Wilmut

  2. T.H. Morgan

  3. Robert Briggs

  4. Thomas King


Correct Option: A
Explanation:

Dolly is the first sheep which was developed by the technique of cloning by Ian Wilmut in the year 1997. The sheep was developed from the diploid body cell. The somatic cell from the mother sheep was taken and the nucleus was injected into the egg cell which was cultured and transferred into the surrogate mother. This method is known as nuclear transfer. The sheep Dolly was identical in the characters with the mother who donated the diploid nucleus from the body cell.  

Thus, the correct answer is option A.

The following are the events in the formation of the first cloned animal the sheep Dolly.
a) Removal of haploid nucleus from the ovum.
b) Implantation of ovum with diploid nucleus into the surrogate mother.
c) Collection of udder cell from the sheep.
d) Injection of diploid nucleus of udder cell into the enucleated ovum.
e) Development of a young clone.The correct sequential order of these events is ________

  1. abcde

  2. cabed

  3. cadbe

  4. edcba


Correct Option: A

It is advantageous to use a vector having multiple cloning sites, as it ___________________.

  1. Contains many copies of a cloned gene

  2. Contains many copies of the same restriction enzyme site

  3. Allows flexibility in the choice of restriction enzymes

  4. Allows flexibility in the choice of genes for cloning


Correct Option: A

This is not a GMO.

  1. Bt brinjal

  2. Golden rice

  3. Tracy

  4. Dolly


Correct Option: D

Efforts to repeat the cloning of Dolly (the sheep) have been unsuccessful. The scientists who claim to have cloned Dolly have been challenged to produce additional evidence that Dolly is really derived from an adult cell (an originally claimed), rather than a foetal cell which might have contaminated the experiment (as the sceplor suggest). Which of the following could provide evidence that Dolly was created from an adult cell, rather than a foetal cell?

  1. Dolly's DNA fingerprints

  2. The heterozygosity of random pieces of Dolly's DNA

  3. The melting point of Dolly's DNA

  4. The length of Dolly's telomeres


Correct Option: A
Explanation:
Dolly was important because she was the first mammal to be cloned from an adult cell. Her birth proved that specialised cells could be used to create an exact copy of the animal they came from. Dolly's DNA fingerprints could provide evidence that Dolly was created from an adult cell.
So the correct answer is 'Dolly's DNA fingerprint'.

Efforts to repeat the cloning of Dolly the sheep have been unsuccessful. The scientists who claim to have cloned Dolly have been challenged to produce additional evidence that Dolly is really derived from an adult cell (as originally claimed), rather than fetal cells which might have contaminated the experiment (as the skeptics suggest). Which of the following could provide evidence that Dolly was created from an adult cell, rather than a fetal cell

  1. Dolly's DNA finger prints

  2. The heterozygosity of random pieces of Dolly's DNA

  3. The melting point of Dolly's DNA

  4. The length of Dolly's telomeres

  5. Dolly's biological clock


Correct Option: D
Explanation:

Telomeres are sections of DNA found at the end of each chromosome. When the chromosomes are replicated during cell division a small portion of the telomeres are lost and thus, they get shorter with the animal's age due to cell division. This led to speculation in the press that Dolly's death was that she could have been born with a genetic age of six years, the same age as the sheep from which she was cloned. One basis for this idea was the finding that Dolly's telomeres were short, which is typically a result of the aging process.

Which of the following statements is incorrect about Dolly, the clone?

  1. Dolly was developed from a cell taken from the mammary gland of Scottish blackface ewe and an unfertilized egg obtained from Finn Dorsett sheep

  2. The egg produced by the fusion was implanted into Scottish blackface ewe

  3. Dolly was identical to Fin Dorsett sheep and was called its done

  4. None of these


Correct Option: A
Explanation:

  • Dolly was born on July 5, 1996, at Roslin Institute, the first mammal known to be cloned.
  •  A cell taken from the mammary gland of a 6-year-old Finn Dorset ewe was cloned through a technique known as nuclear transfer. 
  • The reproductive egg cells were removed from another female sheep, a ewe of a Scottish Blackface. 
  • Scottish Blackface egg cells were then fertilized with the genetic material from the Finn Dorset mammary cells and they fertilized cell was transferred to the uterus of the surrogate mother. 
  • On July 5, 1996, Dolly was born from one of the surrogate Blackface ewes which were identical to the Finn Dorset sheep. 

Thus, the correct answer is option A.

Cloning is the production of an exact copy of a cell, any other living part of a complete organism. A sheep named Dolly was the first mammal to be cloned by Ian Wilmut and his colleagues at the Roslin Institute in Edinburgh. Find out the incorrect statements about the cloning of Dolly.

(i) Dolly was born on 5th July 1996.
(ii) Dolly was given birth by the Finn Dorset sheep.
(iii) Dolly was found to be absolutely identical to the Scottish blackface ewe.
(iv) The nucleus of the mammary gland cell from the Finn Dorsett sheep was inserted into the egg of the Scottish blackface ewe whose nucleus had been removed.

  1. (i) only

  2. (i) and (iii) only

  3. (i), (ii) and (iii) only

  4. All of the above


Correct Option: D
Explanation:

Dolly was born on July 5, 1996, at Roslin Institute, the first mammal known to be cloned. A cell taken from the mammary gland of a 6-year-old Finn Dorset ewe was cloned through a technique known as nuclear transfer. The reproductive egg cells were removed from another female sheep, a ewe of a Scottish Blackface. Scottish Blackface egg cells were then fertilized with the genetic material from the Finn Dorset mammary cells and they fertilized cell was transferred to the uterus of the surrogate mother. On July 5, 1996, Dolly was born from one of the surrogate Blackface ewes which were identical to the Finn Dorset sheep.

- Hide questions