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Bioinformatics Test (Genomics)

Description: Get complete study material and test for basic knowledge in Bio-informatics by covering Bioinfo Test,Bioinformatics Test,Bio-informatics Test
Number of Questions: 89
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Tags: Bioinfo Test Bioinformatic Test Bio informatics Test Genome Sequencing and Human Genome Project Human Genome Project
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Which one of the following does not come under the classification of databases on the basis of types of data?

  1. Nucleotide sequence

  2. Protein sequence

  3. Primary databases

  4. Metabolic pathway


Correct Option: C

How often is the Genbank updated?

  1. Weekly

  2. Daily

  3. Monthly

  4. Yearly


Correct Option: B

Which of the following can be used as an identifier in Genbank?

  1. Entry Name

  2. Locus

  3. Both of these

  4. None of these


Correct Option: B

What is the submission system for EBI?

  1. Webin

  2. Saskura

  3. Bankit

  4. Entrez


Correct Option: A

Which of the following is a literature database?

  1. GEO

  2. PubMed

  3. EST

  4. MMDB


Correct Option: B

The fasta format file starts with

  1. <

  2. >

  3. start

  4. origin


Correct Option: B

What does PDB stand for?

  1. Public DNA Bank

  2. Protein Data Bank

  3. Protein DNA Bank

  4. Public Databases


Correct Option: B

The Genbank format sequence starts with

  1. origin

  2. sequence

  3. start

  4. None of these


Correct Option: A

PDB is managed by

  1. NIH

  2. RCSB

  3. EBI

  4. PIR


Correct Option: B

In CATH, T represents

  1. torsion

  2. topology

  3. target

  4. tRNA


Correct Option: B

ExPASy proteomics server is used for

  1. nucleic acid sequence and structure analysis

  2. protein sequence and structure analysis

  3. chemical analysis

  4. all of these


Correct Option: B

Which of the following is an automated comparative protein modeling server?

  1. BLAST

  2. VAST

  3. SWISS-MODEL

  4. DALI


Correct Option: C

ClustalW is used for

  1. structure prediction

  2. motif analysis

  3. multiple sequence alignment

  4. all of these


Correct Option: C

The first biological database was made by

  1. Dayhoff

  2. Darwin

  3. Pauling

  4. Markov


Correct Option: A

What is the expanded form of KEGG, a molecular database?

  1. Kyoto Expression of Genes and Genomes

  2. Kyoto Encyclopedia of Genes and Genomes

  3. Kyoto Expression of Genotypes and Genomes

  4. Kyoto Encyclopedia of Genes and Genotypes


Correct Option: B

On which of the following sites are e-books available?

  1. EMBL

  2. NCBI

  3. RCSB

  4. PIR


Correct Option: B

1Hae is an ID of which of the following databases?

  1. EMBL

  2. Genbank

  3. PDB

  4. Uniprot


Correct Option: C

Which of the following is a freely accessible database of protein and genetic interactions?

  1. GOD

  2. Motif

  3. BIOGRID

  4. None of these


Correct Option: C

Which of the following servers predicts the presence and location of signal peptide cleavage sites?

  1. Sigpred

  2. SignalI

  3. SignalP

  4. Sigprepred


Correct Option: C

Before analyzing a sequence, it can be converted into different formats using:

  1. formcon

  2. readseq

  3. readcon

  4. confor


Correct Option: D

Gene prediction tool at NCBI is

  1. genscan

  2. genefinder

  3. ORF finder

  4. None of these


Correct Option: B

How many frames of translation does the translate tool at ExPASy provide?

  1. Three

  2. Four

  3. Five

  4. Six


Correct Option: D

Characters homologous with conserved function are known as

  1. analogues

  2. orthologues

  3. paralogues

  4. xenologues


Correct Option: A

Which type of PAM matrix is commonly used?

  1. PAM100

  2. PAM150

  3. PAM200

  4. PAM250


Correct Option: C

Which type of BLOSUM matrix is commonly used?

  1. BLOSUM62

  2. BLOSUM72

  3. BLOSUM82

  4. BLOSUM92


Correct Option: A

Pair-wise alignment is used for best matching of

  1. local alignment

  2. global alignment

  3. Both 1 and 2

  4. None of these


Correct Option: C

Which of the following tools is used for local alignment?

  1. BLAST

  2. ClustalW

  3. ORF Finder

  4. Genscan


Correct Option: C

Which of the following alignments can be used for phylogenetic analysis?

  1. Pairwise alingment

  2. Multiple alignment

  3. Both 1 and 2

  4. None of these


Correct Option: A

Phylogenetic analysis tools include

  1. phylip

  2. PAUP

  3. Both 1 and 2

  4. None of these


Correct Option: D

Secondary structure is predicted by

  1. GOR

  2. COILS

  3. Nnpred

  4. Any of the above


Correct Option: B

Which of the following tools is used for primary structure analysis?

  1. SAPS

  2. PAPS

  3. PrimAna

  4. PriPred


Correct Option: A

Homology Modelling server is built on

  1. SWISS-MODEL

  2. 3DPSSM

  3. Phyre

  4. Rosetta


Correct Option: D

3D PSSM predicts tertiary structure through

  1. homology

  2. threading

  3. abinitio

  4. Any of the above


Correct Option: C

Which of the following systems is used for searching NCBI data?

  1. Entrez

  2. SRS

  3. Google

  4. Bankit


Correct Option: A

Quaternary structure is predicted by

  1. SWISS-MODEL

  2. mercury

  3. mericity

  4. quantum


Correct Option: B

Abinitio approach of tertiary prediction is achieved by

  1. SWISS-MODEL

  2. 3DPSSM

  3. phyre

  4. rosetta


Correct Option: C

The mathematical representation of conserved region is known as

  1. motif

  2. profile

  3. pattern

  4. module


Correct Option: A

__________ finds structural and sequence motifs in protein sequences.

  1. Patsearch

  2. Prosear

  3. ProfileScan

  4. Prof


Correct Option: A

The tool used in NCBI to identify similar protein 3 D' structures is

  1. DALI

  2. LUDI

  3. VAST

  4. BLAST


Correct Option: C

What does EST stan for?

  1. Expressed Sequence Tags

  2. Extreme Sequence Tags

  3. Extended Sequence Tags

  4. Excluded Sequence Tags


Correct Option: A

Vadar is used for

  1. alignment

  2. structure prediction

  3. structure validation

  4. None of the above


Correct Option: C

Who among the following coined the term Pharmacophore?

  1. Pauling

  2. Ehrlich

  3. Koshland

  4. Watson


Correct Option: C

Which of the following produces the abinitio prediction of protein function from the sequence?

  1. ProtFun

  2. PFP Server

  3. Pratt

  4. All of these


Correct Option: C

_________________ is an example of automated docking program.

  1. Hex

  2. Argus Lab

  3. Autodock

  4. VegaZZ


Correct Option: C

Lipinski's rule states that the drug does not have more than ________ hydrogen bond donors.

  1. 2

  2. 3

  3. 4

  4. 5


Correct Option: B

In how many ways, Denovo designing can be used for drug designing?

  1. 1

  2. 2

  3. 3

  4. 4


Correct Option: A

What is 'Leads' in gene therapeutics?

  1. A chemical

  2. A structure guided drug

  3. A prospective drug

  4. All of these


Correct Option: D

ADME-TOX Prediction tool is

  1. ADME predictor

  2. ADME pr

  3. ADME cal

  4. None of these


Correct Option: A

What is Entrez?

  1. A proteomic search engine

  2. A programme key word

  3. Starting code of a sequence analysis

  4. None of these


Correct Option: A

_________can approve a proposed clinical trial for drug designing.

  1. The DCGI

  2. DIG

  3. The President

  4. The Prime Minister


Correct Option: A

The study/studies of the effects of drugs on tissues and organs is/are called

  1. Pharmacodynamcis

  2. Pharmacokinetics

  3. Pharmacophore

  4. All of the above


Correct Option: D

________________ is a/are 3D protein viewer(s).

  1. Marvin space

  2. Rasmol

  3. Swiss PDB Viewer

  4. All of these


Correct Option: D

____________ tool(s) is/are used for Pattern construction.

  1. Pratt

  2. Patcons

  3. Both 1 and 2

  4. None of these


Correct Option: C

Designing a drug molecule atom by atom against a receptor or target is known as

  1. denovo

  2. QSAR

  3. pharmacophore mapping

  4. docking


Correct Option: A

How many patients can be studied for a clinical Phase II trial?

  1. 10-15

  2. 20-25

  3. 30-35

  4. 40-45


Correct Option: B

In how many centres, clinical trials should be carried out?

  1. 1-2

  2. 2-3

  3. 3-4

  4. 4-5


Correct Option: C

Clinical trials for vaccines contain _________ phase/s.

  1. one

  2. two

  3. three

  4. four


Correct Option: C

Pathway prediction system of UM-BBD predicts pathway from

  1. SMILES

  2. structures

  3. Both 1 and 2

  4. None of these


Correct Option: A

A traditional chemist can synthesize _____________ compounds per year.

  1. 100-200

  2. 200-300

  3. 300-400

  4. 400-500


Correct Option: A

When was the Human Genome Project formally proposed?

  1. 1975

  2. 1985

  3. 1995

  4. 2005


Correct Option: B

Which of the following pathway databases is based on reference pathway maps?

  1. Metacyc

  2. Ecocyc

  3. KEGG pathway

  4. UM-BBD


Correct Option: A

BioEdit is used for

  1. similarity studies

  2. structure prediction

  3. profile search

  4. motif search


Correct Option: B

Which sequencing method is efficiently helpful for the Human Genome Project?

  1. Sanger method

  2. Maxm-Gilbert method

  3. Whole Genome Shotgun

  4. None of these


Correct Option: C

What type of recombination vector was generally recommended for HGP?

  1. Plasmid

  2. Cosmid

  3. BAC

  4. YAC


Correct Option: C

When was the work on Human Genome Project started officially?

  1. 1970

  2. 1980

  3. 1990

  4. 2000


Correct Option: C

Which component(s) of Marvin Beans is/are used for structure drawing?

  1. Marvin Sketch

  2. Marvin View

  3. Marvin space

  4. All of the above


Correct Option: A

When was the Human genome sequencing initiated?

  1. 1996

  2. 1997

  3. 1998

  4. 1999


Correct Option: D

When was the first completed report of Human Genome released?

  1. 2000

  2. 2001

  3. 2002

  4. 2003


Correct Option: A

How many Protein coding genes might be present in the Human Genome?

  1. 10, 000

  2. 40, 000

  3. 80, 000

  4. None of these


Correct Option: B

Who coined the term Artificial Intelligence?

  1. John McCarthy

  2. Watson

  3. Meselson

  4. George Mitchel


Correct Option: A

Ensembl is maintained by

  1. NCBI

  2. EBI

  3. RCSB

  4. NLM


Correct Option: B

What is the database used in ensembl?

  1. Oracle

  2. MS-Access

  3. Mysql

  4. All of the above


Correct Option: C

How many species' support was provided by Ensemble in the 47th release in 2007?

  1. 55

  2. 45

  3. 35

  4. 25


Correct Option: C

What percentage of Human Genome has been sequenced properly till date (2011)?

  1. 50%

  2. 60%

  3. 94%

  4. 84%


Correct Option: C

The data mining tool used to analyse ensemble is

  1. chime

  2. rasmol

  3. biomart

  4. None of these


Correct Option: C

Speech recognition softwares work on the basis of

  1. cobalt

  2. aluminium

  3. language

  4. None of these


Correct Option: B

Which of the following is a/are protein sequence database(s)?

  1. Uniprot

  2. PIR

  3. Swiss-prot

  4. All of the above


Correct Option: D

How many groups are involved in HGP?

  1. 10

  2. 20

  3. 30

  4. 40


Correct Option: B

________is the program used for natural selection and artificial phenotype selection.

  1. Genetic algorithm

  2. MOD

  3. Clustal W

  4. None of these


Correct Option: A

On which of the following fields are robotics based?

  1. Cobalt

  2. Mysql

  3. AI

  4. All of the above


Correct Option: C

_______ is an interconnected group of artificial neurons and processes information using a connectionist approach to computation.

  1. Neural-network

  2. Network

  3. Inter-network

  4. Intra-network


Correct Option: A

A large genome annotated database is called

  1. genbank

  2. uniprot

  3. ensemble

  4. MMDB


Correct Option: C

tRNA genes are identified by using

  1. tRNA scan

  2. translate tool

  3. chime

  4. hex


Correct Option: A

How many SNPs were present in the Human Genome, reported by HGP?

  1. 2.2 million

  2. 2.1 million

  3. 3.3 billion

  4. 4.2 billion


Correct Option: B

________________ is a database that provides comprehensive information on mammalian micro RNAs.

  1. Argonaute

  2. RDP

  3. tRNADB

  4. None of these


Correct Option: A

The generation of messenger RNA expression profiles is referred to as

  1. transcription

  2. trasncriptomics

  3. genomics

  4. RNA syn


Correct Option: B

Hex software is used for

  1. alignment

  2. viewing

  3. docking

  4. None of these


Correct Option: C

Name the software(s) for neural network.

  1. SNNS

  2. Emergent

  3. Java NNS

  4. All of the above


Correct Option: D
Explanation:

Option 4 is the correct answer.

Name the software for Natural Language Processing.

  1. OpenNLP

  2. SPSS

  3. SAS

  4. None of these


Correct Option: A
Explanation:

Option 1 is the correct answer.

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