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Pharmaceutical Analysis

Description: This quiz covers various concepts and techniques related to Pharmaceutical Analysis.
Number of Questions: 15
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Tags: pharmaceutical analysis drug analysis drug quality control
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Which of the following techniques is used to separate and identify the components of a drug product?

  1. Chromatography

  2. Spectrophotometry

  3. Titration

  4. Polarography

Show answer
Correct Option: A
Explanation:

Chromatography is a technique used to separate and identify the components of a drug product by their different rates of movement through a stationary phase.

What is the purpose of performing a dissolution test on a drug product?

  1. To determine the rate at which the drug dissolves in a solvent

  2. To determine the stability of the drug product

  3. To determine the purity of the drug product

  4. To determine the bioavailability of the drug product

Show answer
Correct Option: A
Explanation:

A dissolution test is performed to determine the rate at which the drug dissolves in a solvent, which is important for ensuring the bioavailability of the drug product.

What is the principle behind spectrophotometric analysis in pharmaceutical analysis?

  1. Absorption of light by the drug molecule

  2. Emission of light by the drug molecule

  3. Refraction of light by the drug molecule

  4. Scattering of light by the drug molecule

Show answer
Correct Option: A
Explanation:

Spectrophotometric analysis in pharmaceutical analysis is based on the principle that drug molecules absorb light at specific wavelengths, which can be used to identify and quantify the drug.

What is the role of pH in the stability of pharmaceutical products?

  1. pH affects the solubility of the drug

  2. pH affects the chemical stability of the drug

  3. pH affects the physical stability of the drug

  4. All of the above

Show answer
Correct Option: D
Explanation:

pH can affect the solubility, chemical stability, and physical stability of pharmaceutical products.

What is the purpose of performing a limit test in pharmaceutical analysis?

  1. To determine the presence or absence of a specific impurity

  2. To determine the concentration of a specific impurity

  3. To determine the identity of a specific impurity

  4. To determine the source of a specific impurity

Show answer
Correct Option: A
Explanation:

A limit test is performed to determine the presence or absence of a specific impurity in a drug product.

Which of the following techniques is used to identify the functional groups present in a drug molecule?

  1. Infrared spectroscopy

  2. Nuclear magnetic resonance spectroscopy

  3. Mass spectrometry

  4. Ultraviolet spectroscopy

Show answer
Correct Option: A
Explanation:

Infrared spectroscopy is used to identify the functional groups present in a drug molecule by analyzing the absorption of infrared radiation by the molecule.

What is the purpose of performing a potency assay on a drug product?

  1. To determine the concentration of the active ingredient in the drug product

  2. To determine the stability of the drug product

  3. To determine the purity of the drug product

  4. To determine the bioavailability of the drug product

Show answer
Correct Option: A
Explanation:

A potency assay is performed to determine the concentration of the active ingredient in a drug product.

What is the difference between qualitative and quantitative analysis in pharmaceutical analysis?

  1. Qualitative analysis identifies the components of a drug product, while quantitative analysis determines their concentrations

  2. Qualitative analysis determines the components of a drug product, while quantitative analysis identifies their concentrations

  3. Qualitative analysis identifies the impurities in a drug product, while quantitative analysis determines their concentrations

  4. Qualitative analysis determines the impurities in a drug product, while quantitative analysis identifies their concentrations

Show answer
Correct Option: A
Explanation:

Qualitative analysis identifies the components of a drug product, while quantitative analysis determines their concentrations.

Which of the following techniques is used to determine the purity of a drug product?

  1. Chromatography

  2. Spectrophotometry

  3. Titration

  4. Polarography

Show answer
Correct Option: A
Explanation:

Chromatography is used to determine the purity of a drug product by separating and identifying the components of the product.

What is the purpose of performing a stability study on a drug product?

  1. To determine the shelf life of the drug product

  2. To determine the conditions under which the drug product should be stored

  3. To determine the packaging requirements for the drug product

  4. All of the above

Show answer
Correct Option: D
Explanation:

A stability study is performed to determine the shelf life of the drug product, the conditions under which the drug product should be stored, and the packaging requirements for the drug product.

What is the principle behind titrimetric analysis in pharmaceutical analysis?

  1. Neutralization of an acid with a base

  2. Oxidation of a reducing agent with an oxidizing agent

  3. Reduction of an oxidizing agent with a reducing agent

  4. Precipitation of a metal ion with a ligand

Show answer
Correct Option: A
Explanation:

Titrimetric analysis in pharmaceutical analysis is based on the principle of neutralization of an acid with a base.

What is the role of dissolution testing in the development of a drug product?

  1. To determine the rate at which the drug dissolves in a solvent

  2. To determine the stability of the drug product

  3. To determine the bioavailability of the drug product

  4. All of the above

Show answer
Correct Option: D
Explanation:

Dissolution testing is used to determine the rate at which the drug dissolves in a solvent, the stability of the drug product, and the bioavailability of the drug product.

Which of the following techniques is used to determine the identity of a drug molecule?

  1. Infrared spectroscopy

  2. Nuclear magnetic resonance spectroscopy

  3. Mass spectrometry

  4. Ultraviolet spectroscopy

Show answer
Correct Option: C
Explanation:

Mass spectrometry is used to determine the identity of a drug molecule by analyzing the mass-to-charge ratio of the molecule.

What is the purpose of performing a content uniformity test on a drug product?

  1. To determine the uniformity of the drug content in different units of the drug product

  2. To determine the stability of the drug product

  3. To determine the purity of the drug product

  4. To determine the bioavailability of the drug product

Show answer
Correct Option: A
Explanation:

A content uniformity test is performed to determine the uniformity of the drug content in different units of the drug product.

What is the principle behind polarographic analysis in pharmaceutical analysis?

  1. Reduction of a metal ion at a dropping mercury electrode

  2. Oxidation of a metal ion at a dropping mercury electrode

  3. Neutralization of an acid with a base

  4. Precipitation of a metal ion with a ligand

Show answer
Correct Option: A
Explanation:

Polarographic analysis in pharmaceutical analysis is based on the principle of reduction of a metal ion at a dropping mercury electrode.

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