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Glycogen Metabolism: Exploring the Storage and Mobilization of Glucose

Description: Glycogen Metabolism: Exploring the Storage and Mobilization of Glucose
Number of Questions: 15
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Tags: biochemistry glycogen metabolism glucose storage glucose mobilization
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What is the primary function of glycogen in the body?

  1. Storage of glucose for energy

  2. Production of glucose for energy

  3. Regulation of blood sugar levels

  4. Transport of glucose to cells


Correct Option: A
Explanation:

Glycogen serves as a storage form of glucose, providing a readily accessible source of energy for cells when blood sugar levels drop.

Where is glycogen primarily stored in the body?

  1. Liver

  2. Skeletal muscles

  3. Heart

  4. Brain


Correct Option:
Explanation:

Glycogen is mainly stored in the liver and skeletal muscles, with smaller amounts found in the heart and brain.

What is the process of glycogen synthesis called?

  1. Glycogenesis

  2. Glycogenolysis

  3. Gluconeogenesis

  4. Glycolysis


Correct Option: A
Explanation:

Glycogenesis is the process by which glucose is converted into glycogen and stored in the liver and muscles.

Which enzyme is responsible for the breakdown of glycogen into glucose?

  1. Glycogen phosphorylase

  2. Glycogen synthase

  3. Glucose-6-phosphatase

  4. Hexokinase


Correct Option: A
Explanation:

Glycogen phosphorylase catalyzes the breakdown of glycogen into glucose-1-phosphate.

What is the final product of glycogenolysis?

  1. Glucose-1-phosphate

  2. Glucose-6-phosphate

  3. Fructose-1,6-bisphosphate

  4. Pyruvate


Correct Option: A
Explanation:

Glycogenolysis results in the release of glucose-1-phosphate, which is further converted into glucose-6-phosphate and then enters glycolysis.

Which hormone stimulates the breakdown of glycogen in the liver?

  1. Glucagon

  2. Insulin

  3. Epinephrine

  4. Somatostatin


Correct Option: A
Explanation:

Glucagon, produced by the pancreas, promotes the breakdown of glycogen in the liver, releasing glucose into the bloodstream.

What is the process of glycogen mobilization called?

  1. Glycogenesis

  2. Glycogenolysis

  3. Gluconeogenesis

  4. Glycolysis


Correct Option: B
Explanation:

Glycogenolysis refers to the process of breaking down glycogen into glucose molecules for energy production.

Which enzyme is responsible for the conversion of glucose-1-phosphate to glucose-6-phosphate?

  1. Glycogen phosphorylase

  2. Glycogen synthase

  3. Glucose-6-phosphatase

  4. Phosphoglucomutase


Correct Option: D
Explanation:

Phosphoglucomutase catalyzes the conversion of glucose-1-phosphate to glucose-6-phosphate, which can then enter glycolysis.

What is the final product of glycolysis?

  1. Glucose-1-phosphate

  2. Glucose-6-phosphate

  3. Pyruvate

  4. Acetyl-CoA


Correct Option: C
Explanation:

Glycolysis, the first stage of cellular respiration, converts glucose into pyruvate, generating energy in the form of ATP.

Which hormone stimulates the breakdown of glycogen in skeletal muscles?

  1. Glucagon

  2. Insulin

  3. Epinephrine

  4. Somatostatin


Correct Option: C
Explanation:

Epinephrine, also known as adrenaline, triggers the breakdown of glycogen in skeletal muscles, providing energy during physical activity.

What is the role of glucose-6-phosphatase in glycogen metabolism?

  1. Synthesis of glycogen

  2. Breakdown of glycogen

  3. Conversion of glucose-1-phosphate to glucose-6-phosphate

  4. Release of glucose from the liver


Correct Option: D
Explanation:

Glucose-6-phosphatase catalyzes the removal of the phosphate group from glucose-6-phosphate, allowing glucose to be released from the liver into the bloodstream.

Which enzyme is responsible for the synthesis of glycogen from glucose-1-phosphate?

  1. Glycogen phosphorylase

  2. Glycogen synthase

  3. Glucose-6-phosphatase

  4. Phosphoglucomutase


Correct Option: B
Explanation:

Glycogen synthase catalyzes the addition of glucose-1-phosphate to the growing glycogen chain during glycogen synthesis.

What is the primary role of glycogen in skeletal muscles?

  1. Storage of glucose for energy

  2. Production of glucose for energy

  3. Regulation of blood sugar levels

  4. Transport of glucose to cells


Correct Option: A
Explanation:

In skeletal muscles, glycogen serves as a readily available energy source during muscle contractions.

Which hormone inhibits the breakdown of glycogen?

  1. Glucagon

  2. Insulin

  3. Epinephrine

  4. Somatostatin


Correct Option: B
Explanation:

Insulin, produced by the pancreas, promotes the storage of glucose in the form of glycogen and inhibits glycogen breakdown.

What is the fate of pyruvate produced during glycolysis?

  1. Conversion to acetyl-CoA

  2. Conversion to glucose-1-phosphate

  3. Conversion to glucose-6-phosphate

  4. Conversion to fructose-1,6-bisphosphate


Correct Option: A
Explanation:

Pyruvate, generated in glycolysis, is converted into acetyl-CoA, which enters the citric acid cycle for further energy production.

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