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Hormones and Their Actions (GATE - XL)

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Number of Questions: 15
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Tags: GAte Hormones and Their Actions
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Which of the following hormones inhibits gastric secretion and motility?

  1. Erythropoietin

  2. Gastrin

  3. GIP

  4. CCK

  5. Secretin


Correct Option: C
Explanation:

Correct answer. Gastric inhibitory peptide (GIP) inhibits gastric secretion and motility.

Thymosin plays an important role in

P. differentiation of T-lymphocytes Q. production of antibodies R. reabsorption of calcium ions by renal tubules S. conversion of glucose to glycogen

  1. P and Q

  2. P and R

  3. P and S

  4. Q and R

  5. Q and S


Correct Option: A
Explanation:

This option is correct because thymosin is secreted by the thymus gland. Thymosins play a major role in the differentiation of T-lymphocytes, which provide cell-mediated immunity. In addition, thymosins also promote production of antibodies to provide humoral immunity.

Which of the following are peptide hormones?

  1. ANF
  2. Cortisol
  3. MSH
  4. Testosterone
  5. Vasopressin
  1. 1, 2 and 3

  2. 1, 3 and 5

  3. 2, 3 and 4

  4. 2, 4 and 5

  5. 3, 4 and 5


Correct Option: B
Explanation:

Correct answer. Atrial natriuretic factor (ANF) is a powerful vasodilator and a protein (polypeptide) hormone secreted by heart muscle cells. Melanocyte-stimulating hormones (MSH) are a class of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland. Vasopressin, also known as antidiuretic hormone, is a nine amino acid peptide secreted from the posterior pituitary.

Which of the following hormones are secreted by adrenal medulla?

P. Adrenaline Q. Aldosterone R. Cortisol S. Norepinephrine

  1. P and Q

  2. P and R

  3. P and S

  4. Q and R

  5. R and S


Correct Option: C
Explanation:

The adrenal medulla secretes two hormones called adrenaline or epinephrine and noradrenaline or norepinephrine. These are commonly called catecholamines.

Directions: In the following question, there are two statements, Assertion (A) and Reason (R). Consider both the statements independently and choose the appropriate option.

Assertion (A): Aldosterone is a mineralocorticoid. Reason (R): It helps in the maintenance of electrolytes, body fluid volume, osmotic pressure and blood pressure.

  1. A and R both are correct and R is the correct explanation of A.

  2. A and R both are correct and R is not the correct explanation of A.

  3. A is correct and R is incorrect.

  4. A is incorrect and R is correct.

  5. A and R both are incorrect.


Correct Option: A
Explanation:

Correct answer. Corticoids which regulate the balance of water and electrolytes in our body are called mineralocorticoids. Aldosterone is the main mineralocorticoid in our body. Aldosterone acts mainly at the renal tubules and stimulates the reabsorption of Na+ and water and excretion of K+ and phosphate ions. Thus, aldosterone helps in the maintenance of electrolytes, body fluid volume, osmotic pressure and blood pressure.

Identify the incorrectly matched pair.

  1. PTH : Hypercalcemic hormone

  2. Glucagon : Hypoglycemic hormone

  3. ANF : Blood pressure lowering hormone

  4. FSH : Gonadotropic hormone

  5. Vasopressin : Antidiuretic hormone


Correct Option: B
Explanation:

Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis, resulting in an increased blood sugar (hyperglycemia). Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose uptake and utilisation, resulting in rapid movement of glucose from blood to hepatocytes and adipocytes, resulting in decreased blood glucose levels (hypoglycemia).

Match the following:

 
Column - I
Column - II
P. Melatonin 1. Gastrointestinal tract
Q. Erythropoietin 2. Kidney
R. Cholecystokinin 3. Pineal gland
S. Glucagon 4. Pancreas
  1. P - 1, Q - 2, R - 3, S - 4

  2. P - 2, Q - 1, R - 4, S - 3

  3. P - 3, Q - 2, R - 1, S - 4

  4. P - 4, Q - 3, R - 2, S - 1

  5. P - 1, Q - 2, R - 4, S - 3


Correct Option: C
Explanation:

Correct matching is P - 3, Q - 2, R - 1, S - 4.

Which of the following pituitary hormones are called gonadotrophins?

  1. GH
  2. PRL
  3. TSH
  4. ACTH
  5. LH
  6. FSH
  1. 1 and 2

  2. 2, 4 and 6

  3. 3 and 5

  4. 3, 4 and 6

  5. 5 and 6


Correct Option: C
Explanation:

Luteinising hormone (LH) and follicle stimulating hormone (FSH) stimulate gonadal activity and hence, are called gonadotrophins.

Which of the following statements about parathormone are not correct?

P. Parathormone is produced and secreted by thyroid gland. Q. Parathormone is a steroid hormone. R. Parathormone influences calcium absorption in the small intestine by regulating the metabolism of vitamin D. S. Blood calcium level can be increased by administration of parathormone.

  1. P and Q

  2. P and R

  3. P and S

  4. Q and R

  5. Q and S


Correct Option: A
Explanation:

This option is correct because parathormone or parathyroid hormone is produced and secreted by the parathyroid gland that regulates serum calcium concentration. Parathormone is a polypeptide containing 84 amino acids.

Which of the following pairs is/are not correctly matched?

  1. Serotonin : 5-hydroxytryptamine

  2. Epinephrine : 4,5-β-trihydroxyphenethylamine

  3. Melatonin : N-acetyl-5-methoxytryptamine

  4. Dopamine : 3,4-dihydroxyphenethylamine

  5. All of the above


Correct Option: B
Explanation:

Epinephrine (also known as adrenaline or 4,5-β-trihydroxy-N-methylphenethylamine) is a hormone and a neurotransmitter. Norepinephrine (also known as noradrenaline or 4,5-β-trihydroxyphenethylamine) is a catecholamine with multiple roles including those as a hormone and a neurotransmitter.

Which of the following hormones is secreted by the hypothalamus as well as the digestive tract?

  1. Calcitonin

  2. Corticotropin-releasing hormone

  3. Gastrin

  4. Secretin

  5. Somatostatin


Correct Option: E
Explanation:

Somatostatin is secreted in several locations in the digestive system: stomach, intestine, and delta cells of the pancreas. In hypothalamus, somatostatin is produced by neuroendocrine neurons of the ventro medial nucleus.

Which of the following pairs is not correctly matched?

  1. Calcitonin : Parafollicular cell (source)

  2. Glucagon : Beta cells (source)

  3. MSH : Melanogenesis (function)

  4. Insulin : Diabetes mellitus (disease)

  5. Melatonin : Maintains sleep-wake cycle (function)


Correct Option: B
Explanation:

Glucagon is a peptide hormone, produced by alpha cells of the pancreas. Insulin is a peptide hormone synthesized, packaged and secreted in pancreatic beta cells.

Match the following:

 
Column - I
Column - II
A. Acromegaly 1. Adrenal gland
B. Cushing’s syndrome 2. Anterior pituitary
C. SIADH 3. Posterior pituitary
  1. A - 1, B - 2, C - 3

  2. A - 1, B - 3, C - 2

  3. A - 2, B - 1, C - 3

  4. A - 2, B - 3, C - 1

  5. A - 3, B - 1, C - 2


Correct Option: C
Explanation:

Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (GH) after epiphyseal plate closure at puberty. Cushing's syndrome is a hormonal disorder caused by high levels of cortisol which is produced in the human body by the adrenal gland in the zona fasciculate. Syndrome off Inappropriate Antidiuretic Hormone (SIADH) occurs when excessive levels of adrenocorticotropic hormone (ADH) is secreted from the posterior pituitary.

Which of the following hormones regulates water homeostasis throughout the body?

  1. Thyrocalcitonin

  2. Secretin

  3. Oxytocin

  4. Prolactin

  5. Insulin


Correct Option: B
Explanation:

Secretin, a hormone produced in the S cells of the duodenum, regulates water homeostasis throughout the body, and influences the environment of the duodenum by regulating secretions in the stomach and pancreas.

Which of the following hormones is secreted by pars intermedia region of adenohypophysis of pituitary gland?

  1. GH

  2. TSH

  3. ACTH

  4. MSH


Correct Option: D
Explanation:

Melanocyte stimulating hormone (MSH) is secreted by pars intermedia region of adenohypophysis of pituitary gland.

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