The Department of the Interior is responsible for managing and conserving the nation's natural resources, including public lands, minerals, and wildlife.

The Department of Health and Human Services is responsible for protecting the public health and providing essential human services, including Medicare and Medicaid.

The Department of Defense is responsible for protecting the United States from attack and defending its interests around the world.

The Department of the Treasury is responsible for managing the nation's economy, collecting taxes, and issuing currency.

The Department of Justice is responsible for enforcing the law, protecting civil rights, and providing legal advice to the President and other government agencies.

The Department of Transportation is responsible for managing the nation's transportation system, including roads, highways, airports, and railroads.

The Department of Energy is responsible for managing the nation's energy resources, including fossil fuels, nuclear energy, and renewable energy.

The Department of Labor is responsible for promoting and protecting the nation's labor force, including setting wage and hour standards, enforcing workplace safety regulations, and providing unemployment benefits.

The Department of Education is responsible for managing the nation's education system, including providing financial aid to students, setting educational standards, and conducting research.

The Department of Housing and Urban Development is responsible for managing the nation's housing and urban development, including providing affordable housing, promoting community development, and enforcing fair housing laws.

The Department of Veterans Affairs is responsible for managing the nation's veterans affairs, including providing healthcare, disability benefits, and educational assistance to veterans.

The Department of Homeland Security is responsible for managing the nation's homeland security, including protecting the nation from terrorism, natural disasters, and other threats.

The Department of State is responsible for managing the nation's foreign affairs, including negotiating treaties, conducting diplomacy, and representing the United States abroad.

The Department of Agriculture is responsible for managing the nation's agriculture and food system, including promoting agricultural research, providing financial assistance to farmers, and inspecting food products.