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Bioprocessing Fundamentals

Description: This quiz covers the fundamental concepts and principles of bioprocessing, including cell culture, fermentation, bioseparation, and downstream processing.
Number of Questions: 15
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Tags: bioprocessing cell culture fermentation bioseparation downstream processing
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Which of the following is NOT a common type of bioreactor used in bioprocessing?

  1. Stirred-tank bioreactor

  2. Airlift bioreactor

  3. Fluidized-bed bioreactor

  4. Packed-bed bioreactor

  5. Hollow-fiber bioreactor


Correct Option: D
Explanation:

Packed-bed bioreactors are not commonly used in bioprocessing, as they are typically used for solid-state fermentation, which is not a common bioprocessing technique.

What is the primary purpose of cell culture in bioprocessing?

  1. To produce therapeutic proteins

  2. To study cell biology

  3. To produce vaccines

  4. To produce biofuels

  5. To produce antibiotics


Correct Option: A
Explanation:

Cell culture is primarily used in bioprocessing to produce therapeutic proteins, such as antibodies, hormones, and enzymes, which are used to treat various diseases.

Which of the following is NOT a common type of fermentation process used in bioprocessing?

  1. Batch fermentation

  2. Fed-batch fermentation

  3. Continuous fermentation

  4. Solid-state fermentation

  5. Submerged fermentation


Correct Option: D
Explanation:

Solid-state fermentation is not a common type of fermentation process used in bioprocessing, as it is typically used for the production of enzymes and other products that are not easily produced in liquid culture.

What is the primary purpose of bioseparation in bioprocessing?

  1. To separate cells from the culture medium

  2. To separate the product from the cells

  3. To separate the product from impurities

  4. To separate the product from other products

  5. To separate the product from the bioreactor


Correct Option: B
Explanation:

Bioseparation is primarily used in bioprocessing to separate the product from the cells, which is necessary to obtain a pure and concentrated product.

Which of the following is NOT a common type of downstream processing operation used in bioprocessing?

  1. Filtration

  2. Centrifugation

  3. Chromatography

  4. Crystallization

  5. Drying


Correct Option: E
Explanation:

Drying is not a common type of downstream processing operation used in bioprocessing, as it is typically used for the production of solid products, which are not common in bioprocessing.

What is the primary purpose of downstream processing in bioprocessing?

  1. To purify the product

  2. To concentrate the product

  3. To formulate the product

  4. To package the product

  5. To store the product


Correct Option: A
Explanation:

Downstream processing is primarily used in bioprocessing to purify the product, which is necessary to remove impurities and obtain a pure and concentrated product.

Which of the following is NOT a common type of cell culture medium used in bioprocessing?

  1. Dulbecco's Modified Eagle Medium (DMEM)

  2. Ham's F-12 Medium

  3. RPMI 1640 Medium

  4. Iscove's Modified Dulbecco's Medium (IMDM)

  5. Minimum Essential Medium (MEM)


Correct Option: E
Explanation:

Minimum Essential Medium (MEM) is not a common type of cell culture medium used in bioprocessing, as it is typically used for the culture of specialized cells, such as stem cells.

What is the primary purpose of fermentation in bioprocessing?

  1. To produce biomass

  2. To produce metabolites

  3. To produce biofuels

  4. To produce antibiotics

  5. To produce vaccines


Correct Option: B
Explanation:

Fermentation is primarily used in bioprocessing to produce metabolites, which are small molecules that are produced by microorganisms through metabolic processes.

Which of the following is NOT a common type of bioseparation technique used in bioprocessing?

  1. Filtration

  2. Centrifugation

  3. Chromatography

  4. Extraction

  5. Precipitation


Correct Option: D
Explanation:

Extraction is not a common type of bioseparation technique used in bioprocessing, as it is typically used for the separation of non-polar compounds from polar compounds.

What is the primary purpose of cell culture in bioprocessing?

  1. To produce therapeutic proteins

  2. To study cell biology

  3. To produce vaccines

  4. To produce biofuels

  5. To produce antibiotics


Correct Option: A
Explanation:

Cell culture is primarily used in bioprocessing to produce therapeutic proteins, such as antibodies, hormones, and enzymes, which are used to treat various diseases.

Which of the following is NOT a common type of fermentation process used in bioprocessing?

  1. Batch fermentation

  2. Fed-batch fermentation

  3. Continuous fermentation

  4. Solid-state fermentation

  5. Submerged fermentation


Correct Option: D
Explanation:

Solid-state fermentation is not a common type of fermentation process used in bioprocessing, as it is typically used for the production of enzymes and other products that are not easily produced in liquid culture.

What is the primary purpose of bioseparation in bioprocessing?

  1. To separate cells from the culture medium

  2. To separate the product from the cells

  3. To separate the product from impurities

  4. To separate the product from other products

  5. To separate the product from the bioreactor


Correct Option: B
Explanation:

Bioseparation is primarily used in bioprocessing to separate the product from the cells, which is necessary to obtain a pure and concentrated product.

Which of the following is NOT a common type of downstream processing operation used in bioprocessing?

  1. Filtration

  2. Centrifugation

  3. Chromatography

  4. Crystallization

  5. Drying


Correct Option: E
Explanation:

Drying is not a common type of downstream processing operation used in bioprocessing, as it is typically used for the production of solid products, which are not common in bioprocessing.

What is the primary purpose of downstream processing in bioprocessing?

  1. To purify the product

  2. To concentrate the product

  3. To formulate the product

  4. To package the product

  5. To store the product


Correct Option: A
Explanation:

Downstream processing is primarily used in bioprocessing to purify the product, which is necessary to remove impurities and obtain a pure and concentrated product.

Which of the following is NOT a common type of cell culture medium used in bioprocessing?

  1. Dulbecco's Modified Eagle Medium (DMEM)

  2. Ham's F-12 Medium

  3. RPMI 1640 Medium

  4. Iscove's Modified Dulbecco's Medium (IMDM)

  5. Minimum Essential Medium (MEM)


Correct Option: E
Explanation:

Minimum Essential Medium (MEM) is not a common type of cell culture medium used in bioprocessing, as it is typically used for the culture of specialized cells, such as stem cells.

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