English colonists founded the Jamestown settlement in Virginia in 1607, marking the beginning of permanent European settlement in the American Northeast.

Acadia was a region in the American Northeast that was claimed by both the English and French during the 17th and 18th centuries. It included parts of present-day Maine, New Brunswick, and Nova Scotia.

Boston was a major center of the American Revolution. It was the site of the Boston Massacre, the Boston Tea Party, and the Battle of Bunker Hill.

Delaware was the first state to ratify the U.S. Constitution on December 7, 1787.

The Erie Canal was built in the American Northeast in the 19th century to connect the Atlantic Ocean to the Great Lakes. It was a major transportation route for goods and people.

Boston was a major center of the abolitionist movement. It was the home of William Lloyd Garrison, the editor of the abolitionist newspaper The Liberator.

South Carolina was the first state to secede from the Union during the Civil War on December 20, 1860.

Gettysburg was the site of a major battle during the Civil War from July 1-3, 1863. It was the turning point of the war and resulted in a Union victory.

Wyoming was the first state in the American Northeast to grant women the right to vote in 1869.

Pittsburgh was a major center of the Industrial Revolution in the American Northeast. It was known as the "Steel City" due to its large steel industry.

Massachusetts was the first state in the American Northeast to legalize same-sex marriage in 2004.

New York City is known as the "Big Apple".

Vermont is known for its maple syrup production.

Philadelphia is known for its cheesesteaks.

Maine is known for its lobster industry.