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Pharmacology of Cancer Drugs

Description: Pharmacology of Cancer Drugs
Number of Questions: 15
Created by:
Tags: cancer drugs pharmacology oncology
Attempted 0/15 Correct 0 Score 0

Which of the following is a type of cancer drug that targets the cell cycle?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Antibiotics


Correct Option: B
Explanation:

Antimetabolites are a class of cancer drugs that interfere with the synthesis or function of essential metabolites, such as DNA, RNA, and proteins, thereby inhibiting cell growth and division.

Which of the following is a type of cancer drug that damages DNA?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Antibiotics


Correct Option: A
Explanation:

Alkylating agents are a class of cancer drugs that add alkyl groups to DNA, causing DNA damage and inhibiting cell division.

Which of the following is a type of cancer drug that inhibits topoisomerase enzymes?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Antibiotics


Correct Option: C
Explanation:

Topoisomerase inhibitors are a class of cancer drugs that inhibit topoisomerase enzymes, which are responsible for unwinding and relaxing DNA during replication and transcription. By inhibiting topoisomerase, these drugs cause DNA damage and cell death.

Which of the following is a type of cancer drug that targets microtubules?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Antibiotics


Correct Option: D
Explanation:

Antibiotics are a class of cancer drugs that target microtubules, which are essential for cell division. By inhibiting microtubule function, these drugs prevent cell division and cause cell death.

Which of the following is a type of cancer drug that targets angiogenesis?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Antibiotics


Correct Option: D
Explanation:

Antibiotics are a class of cancer drugs that target angiogenesis, which is the formation of new blood vessels. By inhibiting angiogenesis, these drugs cut off the blood supply to tumors, causing them to shrink and die.

Which of the following is a type of cancer drug that targets the immune system?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Immunotherapy


Correct Option: D
Explanation:

Immunotherapy is a class of cancer drugs that targets the immune system. These drugs work by either stimulating the immune system to recognize and attack cancer cells or by suppressing the immune system to prevent it from attacking healthy cells.

Which of the following is a common side effect of alkylating agents?

  1. Nausea and vomiting

  2. Hair loss

  3. Bone marrow suppression

  4. All of the above


Correct Option: D
Explanation:

Alkylating agents are known to cause a variety of side effects, including nausea and vomiting, hair loss, and bone marrow suppression.

Which of the following is a common side effect of antimetabolites?

  1. Nausea and vomiting

  2. Diarrhea

  3. Skin rash

  4. All of the above


Correct Option: D
Explanation:

Antimetabolites are known to cause a variety of side effects, including nausea and vomiting, diarrhea, and skin rash.

Which of the following is a common side effect of topoisomerase inhibitors?

  1. Nausea and vomiting

  2. Diarrhea

  3. Hair loss

  4. All of the above


Correct Option: D
Explanation:

Topoisomerase inhibitors are known to cause a variety of side effects, including nausea and vomiting, diarrhea, and hair loss.

Which of the following is a common side effect of antibiotics?

  1. Nausea and vomiting

  2. Diarrhea

  3. Kidney damage

  4. All of the above


Correct Option: D
Explanation:

Antibiotics are known to cause a variety of side effects, including nausea and vomiting, diarrhea, and kidney damage.

Which of the following is a common side effect of immunotherapy?

  1. Nausea and vomiting

  2. Diarrhea

  3. Skin rash

  4. All of the above


Correct Option: D
Explanation:

Immunotherapy is known to cause a variety of side effects, including nausea and vomiting, diarrhea, and skin rash.

Which of the following is a type of cancer drug that targets the PI3K/AKT/mTOR pathway?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. mTOR inhibitors


Correct Option: D
Explanation:

mTOR inhibitors are a class of cancer drugs that target the PI3K/AKT/mTOR pathway, which is involved in cell growth, proliferation, and survival. By inhibiting mTOR, these drugs block the growth and spread of cancer cells.

Which of the following is a type of cancer drug that targets the BCR-ABL fusion protein?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Tyrosine kinase inhibitors


Correct Option: D
Explanation:

Tyrosine kinase inhibitors are a class of cancer drugs that target the BCR-ABL fusion protein, which is found in chronic myeloid leukemia (CML). By inhibiting the BCR-ABL fusion protein, these drugs block the growth and spread of CML cells.

Which of the following is a type of cancer drug that targets the HER2 protein?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. HER2 inhibitors


Correct Option: D
Explanation:

HER2 inhibitors are a class of cancer drugs that target the HER2 protein, which is overexpressed in some types of breast cancer. By inhibiting the HER2 protein, these drugs block the growth and spread of breast cancer cells.

Which of the following is a type of cancer drug that targets the PD-1/PD-L1 pathway?

  1. Alkylating agents

  2. Antimetabolites

  3. Topoisomerase inhibitors

  4. Immune checkpoint inhibitors


Correct Option: D
Explanation:

Immune checkpoint inhibitors are a class of cancer drugs that target the PD-1/PD-L1 pathway, which is involved in regulating the immune system. By inhibiting the PD-1/PD-L1 pathway, these drugs release the brakes on the immune system, allowing it to recognize and attack cancer cells.

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