0

Drug-Nutrient Interactions and Dietary Considerations

Description: This quiz is designed to assess your knowledge of drug-nutrient interactions and dietary considerations. It covers topics such as the effects of drugs on nutrient absorption, metabolism, and excretion, as well as the impact of dietary factors on drug efficacy and safety.
Number of Questions: 15
Created by:
Tags: drug-nutrient interactions dietary considerations pharmacokinetics pharmacodynamics
Attempted 0/15 Correct 0 Score 0

Which of the following drugs can interfere with the absorption of vitamin B12?

  1. Metformin

  2. Omeprazole

  3. Colchicine

  4. All of the above


Correct Option:
Explanation:

Metformin, omeprazole, and colchicine can all interfere with the absorption of vitamin B12. Metformin can decrease the absorption of vitamin B12 in the small intestine, while omeprazole and colchicine can interfere with the absorption of vitamin B12 in the stomach.

Which of the following nutrients can interfere with the metabolism of warfarin?

  1. Vitamin K

  2. Vitamin C

  3. Iron

  4. Calcium


Correct Option:
Explanation:

Vitamin K is a cofactor for the enzyme that converts warfarin to its inactive form. Therefore, high intake of vitamin K can decrease the effectiveness of warfarin.

Which of the following drugs can increase the excretion of potassium?

  1. Thiazide diuretics

  2. Loop diuretics

  3. ACE inhibitors

  4. Beta-blockers


Correct Option:
Explanation:

Thiazide diuretics can increase the excretion of potassium by inhibiting the reabsorption of potassium in the kidneys.

Which of the following dietary factors can increase the risk of bleeding in patients taking warfarin?

  1. High intake of vitamin K

  2. High intake of vitamin C

  3. High intake of iron

  4. High intake of alcohol


Correct Option:
Explanation:

Alcohol can interfere with the metabolism of warfarin and increase the risk of bleeding.

Which of the following drugs can interfere with the absorption of iron?

  1. Tetracycline

  2. Ciprofloxacin

  3. Calcium supplements

  4. All of the above


Correct Option:
Explanation:

Tetracycline, ciprofloxacin, and calcium supplements can all interfere with the absorption of iron. Tetracycline and ciprofloxacin can chelate iron and prevent its absorption in the small intestine, while calcium supplements can bind to iron and form insoluble complexes that are not absorbed.

Which of the following nutrients can interfere with the metabolism of phenytoin?

  1. Vitamin D

  2. Vitamin C

  3. Folic acid

  4. All of the above


Correct Option:
Explanation:

Vitamin D, vitamin C, and folic acid can all interfere with the metabolism of phenytoin. Vitamin D can increase the metabolism of phenytoin, while vitamin C and folic acid can decrease the metabolism of phenytoin.

Which of the following drugs can increase the excretion of calcium?

  1. Loop diuretics

  2. Thiazide diuretics

  3. ACE inhibitors

  4. Beta-blockers


Correct Option:
Explanation:

Loop diuretics can increase the excretion of calcium by inhibiting the reabsorption of calcium in the kidneys.

Which of the following dietary factors can increase the risk of bone loss in patients taking glucocorticoids?

  1. High intake of calcium

  2. High intake of vitamin D

  3. High intake of protein

  4. High intake of alcohol


Correct Option:
Explanation:

Alcohol can interfere with the metabolism of glucocorticoids and increase the risk of bone loss.

Which of the following drugs can interfere with the absorption of folate?

  1. Methotrexate

  2. Sulfasalazine

  3. Trimethoprim

  4. All of the above


Correct Option:
Explanation:

Methotrexate, sulfasalazine, and trimethoprim can all interfere with the absorption of folate. Methotrexate and sulfasalazine can inhibit the transport of folate across the intestinal mucosa, while trimethoprim can interfere with the metabolism of folate.

Which of the following nutrients can interfere with the metabolism of methotrexate?

  1. Folic acid

  2. Vitamin B12

  3. Iron

  4. Calcium


Correct Option:
Explanation:

Folic acid is a cofactor for the enzyme that converts methotrexate to its inactive form. Therefore, high intake of folic acid can decrease the effectiveness of methotrexate.

Which of the following drugs can increase the excretion of magnesium?

  1. Loop diuretics

  2. Thiazide diuretics

  3. ACE inhibitors

  4. Beta-blockers


Correct Option:
Explanation:

Loop diuretics can increase the excretion of magnesium by inhibiting the reabsorption of magnesium in the kidneys.

Which of the following dietary factors can increase the risk of muscle weakness in patients taking statins?

  1. High intake of grapefruit juice

  2. High intake of alcohol

  3. High intake of caffeine

  4. High intake of red meat


Correct Option:
Explanation:

Grapefruit juice can interfere with the metabolism of statins and increase the risk of muscle weakness.

Which of the following drugs can interfere with the absorption of vitamin A?

  1. Mineral oil

  2. Orlistat

  3. Cholestyramine

  4. All of the above


Correct Option:
Explanation:

Mineral oil, orlistat, and cholestyramine can all interfere with the absorption of vitamin A. Mineral oil can prevent the absorption of vitamin A in the small intestine, while orlistat and cholestyramine can bind to vitamin A and prevent its absorption.

Which of the following nutrients can interfere with the metabolism of cyclosporine?

  1. Grapefruit juice

  2. St. John's wort

  3. Garlic

  4. All of the above


Correct Option:
Explanation:

Grapefruit juice, St. John's wort, and garlic can all interfere with the metabolism of cyclosporine. Grapefruit juice and St. John's wort can increase the metabolism of cyclosporine, while garlic can decrease the metabolism of cyclosporine.

Which of the following drugs can increase the excretion of zinc?

  1. Penicillamine

  2. Furosemide

  3. Hydrochlorothiazide

  4. All of the above


Correct Option:
Explanation:

Penicillamine, furosemide, and hydrochlorothiazide can all increase the excretion of zinc. Penicillamine can chelate zinc and increase its excretion in the urine, while furosemide and hydrochlorothiazide can increase the excretion of zinc in the urine by inhibiting its reabsorption in the kidneys.

- Hide questions