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Immunodeficiency Disorders and Their Causes

Description: Immunodeficiency Disorders and Their Causes
Number of Questions: 15
Created by:
Tags: immunology immunodeficiency immune system disorders
Attempted 0/15 Correct 0 Score 0

What is the most common type of primary immunodeficiency disorder?

  1. Severe combined immunodeficiency (SCID)

  2. Common variable immunodeficiency (CVID)

  3. X-linked agammaglobulinemia (XLA)

  4. Wiskott-Aldrich syndrome (WAS)


Correct Option: B
Explanation:

CVID is the most common primary immunodeficiency disorder, affecting approximately 1 in 25,000 people.

Which of the following is a type of secondary immunodeficiency disorder?

  1. HIV/AIDS

  2. Diabetes

  3. Cancer

  4. Lupus


Correct Option: A
Explanation:

HIV/AIDS is a type of secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV), which attacks and destroys immune cells.

What is the function of antibodies in the immune system?

  1. To recognize and bind to specific antigens

  2. To produce cytokines

  3. To phagocytose foreign particles

  4. To activate complement proteins


Correct Option: A
Explanation:

Antibodies are proteins produced by B cells that recognize and bind to specific antigens, marking them for destruction by other immune cells.

What is the role of T cells in the immune system?

  1. To kill infected cells

  2. To help B cells produce antibodies

  3. To regulate immune responses

  4. All of the above


Correct Option: D
Explanation:

T cells play a variety of roles in the immune system, including killing infected cells, helping B cells produce antibodies, and regulating immune responses.

Which of the following is a common symptom of immunodeficiency disorders?

  1. Frequent infections

  2. Delayed wound healing

  3. Autoimmune disorders

  4. All of the above


Correct Option: D
Explanation:

Common symptoms of immunodeficiency disorders include frequent infections, delayed wound healing, and autoimmune disorders.

How is SCID treated?

  1. Bone marrow transplant

  2. Gene therapy

  3. Intravenous immunoglobulin (IVIG) therapy

  4. All of the above


Correct Option: D
Explanation:

SCID can be treated with bone marrow transplant, gene therapy, IVIG therapy, or a combination of these treatments.

What is the prognosis for patients with CVID?

  1. Good with early diagnosis and treatment

  2. Poor, even with treatment

  3. Varies depending on the severity of the disorder

  4. There is no cure for CVID


Correct Option: A
Explanation:

With early diagnosis and treatment, the prognosis for patients with CVID is generally good.

Which of the following is a risk factor for developing an immunodeficiency disorder?

  1. Family history of immunodeficiency disorders

  2. HIV infection

  3. Diabetes

  4. All of the above


Correct Option: D
Explanation:

Risk factors for developing an immunodeficiency disorder include family history of immunodeficiency disorders, HIV infection, diabetes, and certain medications.

What is the most common type of inherited immunodeficiency disorder?

  1. SCID

  2. CVID

  3. XLA

  4. WAS


Correct Option: A
Explanation:

SCID is the most common type of inherited immunodeficiency disorder, affecting approximately 1 in 58,000 live births.

Which of the following is a type of phagocytic cell?

  1. Neutrophils

  2. Macrophages

  3. Dendritic cells

  4. All of the above


Correct Option: D
Explanation:

Neutrophils, macrophages, and dendritic cells are all types of phagocytic cells that engulf and destroy foreign particles.

What is the function of the complement system in the immune response?

  1. To help antibodies bind to antigens

  2. To activate phagocytes

  3. To lyse infected cells

  4. All of the above


Correct Option: D
Explanation:

The complement system helps antibodies bind to antigens, activates phagocytes, and lyses infected cells.

Which of the following is a type of cytokine?

  1. Interleukin-2 (IL-2)

  2. Tumor necrosis factor (TNF)

  3. Interferon-gamma (IFN-γ)

  4. All of the above


Correct Option: D
Explanation:

Interleukin-2 (IL-2), tumor necrosis factor (TNF), and interferon-gamma (IFN-γ) are all types of cytokines.

What is the role of the thymus in the immune system?

  1. To produce T cells

  2. To mature T cells

  3. To regulate immune responses

  4. All of the above


Correct Option: D
Explanation:

The thymus produces, matures, and regulates T cells.

Which of the following is a type of innate immune response?

  1. Phagocytosis

  2. Inflammation

  3. Natural killer (NK) cell activity

  4. All of the above


Correct Option: D
Explanation:

Phagocytosis, inflammation, and NK cell activity are all types of innate immune responses.

What is the role of memory cells in the immune system?

  1. To remember past infections

  2. To produce antibodies quickly upon reinfection

  3. To help T cells kill infected cells

  4. All of the above


Correct Option: D
Explanation:

Memory cells remember past infections, produce antibodies quickly upon reinfection, and help T cells kill infected cells.

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