Antibodies

Description: This quiz is designed to test your knowledge about antibodies, their structure, function, and role in the immune system.
Number of Questions: 15
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Tags: antibodies immunology immune system
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What is the primary function of antibodies in the immune system?

  1. To recognize and neutralize foreign substances

  2. To produce white blood cells

  3. To regulate body temperature

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Antibodies are proteins produced by the immune system to recognize and neutralize foreign substances, such as bacteria, viruses, and toxins.

Which type of immune response involves the production of antibodies?

  1. Humoral immune response

  2. Cell-mediated immune response

  3. Innate immune response

  4. Adaptive immune response


Correct Option: A
Explanation:

The humoral immune response is the part of the adaptive immune system that involves the production of antibodies by B cells.

What is the basic structure of an antibody molecule?

  1. Two heavy chains and two light chains

  2. One heavy chain and one light chain

  3. Four heavy chains and four light chains

  4. Two heavy chains and four light chains


Correct Option: A
Explanation:

An antibody molecule consists of two heavy chains and two light chains, which are held together by disulfide bonds.

Which region of an antibody molecule is responsible for binding to specific antigens?

  1. Fab region

  2. Fc region

  3. Hinge region

  4. CDR region


Correct Option: D
Explanation:

The CDR (complementarity-determining region) is the part of the antibody molecule that is responsible for binding to specific antigens.

What is the role of the Fc region of an antibody molecule?

  1. Binding to specific antigens

  2. Activating complement proteins

  3. Binding to Fc receptors on immune cells

  4. Neutralizing toxins


Correct Option: C
Explanation:

The Fc region of an antibody molecule binds to Fc receptors on immune cells, which triggers various immune responses, such as phagocytosis and antibody-dependent cell-mediated cytotoxicity.

Which class of antibodies is most abundant in the blood?

  1. IgG

  2. IgA

  3. IgM

  4. IgD


Correct Option: A
Explanation:

IgG is the most abundant class of antibodies in the blood, accounting for approximately 75% of all antibodies.

Which class of antibodies is primarily found in mucosal secretions, such as saliva and tears?

  1. IgG

  2. IgA

  3. IgM

  4. IgE


Correct Option: B
Explanation:

IgA is the primary class of antibodies found in mucosal secretions, where it helps to protect against infections at mucosal surfaces.

Which class of antibodies is involved in allergic reactions?

  1. IgG

  2. IgA

  3. IgM

  4. IgE


Correct Option: D
Explanation:

IgE is the class of antibodies involved in allergic reactions. It binds to allergens and triggers the release of histamine and other inflammatory mediators from mast cells and basophils.

What is the role of IgM antibodies in the immune response?

  1. They are the first antibodies produced in response to an infection

  2. They are involved in memory responses

  3. They activate complement proteins

  4. They bind to Fc receptors on immune cells


Correct Option: A
Explanation:

IgM antibodies are the first antibodies produced in response to an infection. They are large, multimeric antibodies that can activate complement proteins and bind to Fc receptors on immune cells.

What is the role of memory B cells in the immune response?

  1. They produce antibodies immediately upon re-exposure to an antigen

  2. They help to activate T cells

  3. They differentiate into plasma cells

  4. They produce cytokines


Correct Option: A
Explanation:

Memory B cells are a type of B cell that is generated during an immune response. They remain in the body after the infection has been cleared and can quickly produce antibodies upon re-exposure to the same antigen.

What is the difference between active and passive immunity?

  1. Active immunity is acquired through vaccination, while passive immunity is acquired through infection

  2. Active immunity is acquired through infection, while passive immunity is acquired through vaccination

  3. Active immunity is acquired through contact with an antigen, while passive immunity is acquired through contact with an antibody

  4. Active immunity is acquired through contact with an antibody, while passive immunity is acquired through contact with an antigen


Correct Option:
Explanation:

Active immunity is acquired when the body produces its own antibodies in response to an infection or vaccination. Passive immunity is acquired when antibodies are transferred from one individual to another, either through the placenta or through blood transfusions.

What is the role of antibodies in preventing autoimmune diseases?

  1. They help to distinguish between self and non-self antigens

  2. They help to suppress the immune response

  3. They help to activate the immune response

  4. They help to produce cytokines


Correct Option: A
Explanation:

Antibodies help to distinguish between self and non-self antigens. They bind to non-self antigens and trigger an immune response, while ignoring self antigens.

What is the role of antibodies in cancer immunotherapy?

  1. They help to target and destroy cancer cells

  2. They help to activate the immune response against cancer cells

  3. They help to suppress the immune response against cancer cells

  4. They help to produce cytokines


Correct Option: A
Explanation:

Antibodies can be used in cancer immunotherapy to target and destroy cancer cells. They can be engineered to bind to specific antigens on cancer cells and deliver toxic payloads or activate the immune system against the cancer cells.

What are monoclonal antibodies?

  1. Antibodies produced by a single B cell clone

  2. Antibodies produced by multiple B cell clones

  3. Antibodies produced by T cells

  4. Antibodies produced by macrophages


Correct Option: A
Explanation:

Monoclonal antibodies are antibodies produced by a single B cell clone. They are identical in structure and specificity, and they can be produced in large quantities using hybridoma technology.

What are the potential side effects of antibody-based therapies?

  1. Infusion reactions

  2. Hypersensitivity reactions

  3. Autoimmune reactions

  4. All of the above


Correct Option: D
Explanation:

Antibody-based therapies can have potential side effects, including infusion reactions, hypersensitivity reactions, and autoimmune reactions. These side effects can range from mild to severe and can vary depending on the specific antibody and the individual patient.

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