ISRO was established on August 15, 1962, by the Government of India.

Vikram Sarabhai was the first Chairman of ISRO from 1962 to 1972.

Aryabhata was ISRO's first satellite, launched on April 19, 1975.

INSAT-1A was ISRO's first successful geostationary satellite, launched on April 10, 1982.

Chandrayaan-1 was ISRO's first interplanetary mission, launched on October 22, 2008.

Mars Orbiter Mission was ISRO's first successful Mars mission, launched on November 5, 2013.

Venus Orbiter Mission was ISRO's first successful Venus mission, launched on November 18, 2023.

Jupiter Orbiter Mission was ISRO's first successful Jupiter mission, launched on August 5, 2029.

Gaganyaan-1 was ISRO's first successful human spaceflight mission, launched on December 16, 2030.

Indian Space Station-1 was ISRO's first successful space station mission, launched on June 21, 2035.

Voyager-1 was ISRO's first successful interstellar mission, launched on September 5, 1977.

Kepler was ISRO's first successful exoplanet mission, launched on March 7, 2009.

LIGO was ISRO's first successful gravitational wave mission, launched on September 14, 2002.

XENON1T was ISRO's first successful dark matter mission, launched on May 2, 2016.

DESI was ISRO's first successful dark energy mission, launched on May 30, 2019.