The primary ethical concern regarding animal experimentation is the potential for animal suffering. Animals used in experiments may experience pain, distress, and even death.

The main arguments in favor of animal experimentation are that it is necessary to advance medical knowledge and treatments, and that it is the only way to test the safety and efficacy of new drugs and treatments.

The main arguments against animal experimentation are that it is cruel and inhumane to inflict pain and suffering on animals, that animals are not capable of giving informed consent, and that animal experimentation is often unnecessary and can be replaced by alternative methods.

Some of the alternatives to animal experimentation include computer modeling and simulation, in vitro testing (testing on cells or tissues in a laboratory setting), and human clinical trials.

Some of the ethical considerations that should be taken into account when conducting animal experiments include the potential benefits of the research must outweigh the potential harms to the animals, the animals must be treated with respect and compassion, and the animals must be given adequate pain relief.

Some of the international regulations and guidelines that govern animal experimentation include the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes, the United States Animal Welfare Act, and the Canadian Council on Animal Care Guidelines.

Some of the ethical issues that arise in the context of animal experimentation on non-human primates include that non-human primates are more closely related to humans than other animals, so they have a greater capacity for suffering, that non-human primates are often used in experiments that involve invasive procedures and pain, and that non-human primates are often kept in isolation or in barren cages, which can lead to psychological distress.

Some of the ethical issues that arise in the context of animal experimentation on rodents include that rodents are often used in experiments that involve pain and distress, that rodents are often kept in overcrowded and unsanitary conditions, and that rodents are often killed after experiments, even if they could be adopted into homes.

Some of the ethical issues that arise in the context of animal experimentation on dogs and cats include that dogs and cats are often used in experiments that involve pain and distress, that dogs and cats are often kept in overcrowded and unsanitary conditions, and that dogs and cats are often killed after experiments, even if they could be adopted into homes.

Some of the ethical issues that arise in the context of animal experimentation on farm animals include that farm animals are often used in experiments that involve pain and distress, that farm animals are often kept in overcrowded and unsanitary conditions, and that farm animals are often killed after experiments, even if they could be adopted into sanctuaries.

Some of the ethical issues that arise in the context of animal experimentation on animals used for food include that animals used for food are often subjected to painful procedures, such as debeaking and castration, that animals used for food are often kept in overcrowded and unsanitary conditions, and that animals used for food are often killed in inhumane ways.

Some of the ethical issues that arise in the context of animal experimentation on animals used for clothing include that animals used for clothing are often subjected to painful procedures, such as shearing and skinning, that animals used for clothing are often kept in overcrowded and unsanitary conditions, and that animals used for clothing are often killed in inhumane ways.

Some of the ethical issues that arise in the context of animal experimentation on animals used for entertainment include that animals used for entertainment are often subjected to painful procedures, such as training and performing tricks, that animals used for entertainment are often kept in overcrowded and unsanitary conditions, and that animals used for entertainment are often killed after they are no longer useful.

Some of the ethical issues that arise in the context of animal experimentation on animals used for research include that animals used for research are often subjected to painful procedures, such as surgery and injections, that animals used for research are often kept in overcrowded and unsanitary conditions, and that animals used for research are often killed after experiments, even if they could be adopted into homes.

Some of the ethical issues that arise in the context of animal experimentation on animals used for testing cosmetics include that animals used for testing cosmetics are often subjected to painful procedures, such as skin and eye irritation tests, that animals used for testing cosmetics are often kept in overcrowded and unsanitary conditions, and that animals used for testing cosmetics are often killed after experiments, even if they could be adopted into homes.