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Expression of gene - class-XII

Description: expression of gene
Number of Questions: 62
Created by:
Tags: inherited changes biology
Attempted 0/62 Correct 0 Score 0

RNAi is the important cellular defence in

  1. Prokaryotes

  2. Eukaryotes

  3. All living organism

  4. Viruses


Correct Option: B
Explanation:

Inactivation of RNA by using another RNA is called RNA interference(RNAi). It is used in pest control in tomato plant. It is a cellular defence method. It is applicable to eukaryotes only.

So, the correct option is ‘Eukaryotes’.

Lac-operon is related with _______

  1. Lactose metabolism

  2. Starch metabolism

  3. Lipid metabolism

  4. Protein metabolism


Correct Option: A
Explanation:

Lac-operon refers to the group of genes present in bacteria that are responsible for the metabolism of lactose. There are three genes called LacZ, LacY and LacA that code of beta-galactosidase, permease and transacetylase respectively. They have a common promoter, operator and a regulator gene.

Hence, the correct answer is 'Lactose metabolism'

In prokaryotes, the predominant site for control of gene expression is 

  1. Transcription Initiation

  2. Processing level

  3. Transport of mRNA

  4. Translation level


Correct Option: A
Explanation:

A DNA segment that contributes to phenotype/function is called gene. In prokaryotes, the predominant site for control of gene expression is at Transcription level, where as in eukaryotes, control of gene expression occurs at transcription level, processing level, transport of mRNA, translation level.

So, the correct option is ‘Transcription intiations’.

In E.coli _________________________ genes are grouped in  _______________ operon.

  1. $64,20$

  2. $3,100$

  3. $34,10$

  4. $260,75$


Correct Option: A
Explanation:

In E.coli, a single circular, nacked dsDNA molecule act as a genetic material. It contains 64 genes and are grouped into 20 operons.

So, the correct option is ’64, 20’.

Initiating codon in eukaryotes is

  1. AUG

  2. GUG

  3. UGA

  4. UAG


Correct Option: A

Inheritance of a character is also affected by the promoter and regulatory sequences of a structural gene. Hence, sometimes the regulatory sequences are loosely defined as 

  1. Structural gene 

  2. Regulatory gene

  3. Promoter gene

  4. None of the above


Correct Option: B
Explanation:
A regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences encode regulatory genes. Sometimes the regulatory sequences are loosely defined as regulatory genes because the regulatory sequences of a structural gene affect the inheritance of a character.
So, the correct answer is 'Regulatory gene'.

Functioning of structural genes is controlled by

  1. Operator

  2. Ligase

  3. Regulator gene

  4. Polymerase


Correct Option: C
Explanation:

Operon can be defined as DNA segment having a cluster of genes which are controlled by single promoter. It consists of operator gene and structural genes. The operator gene regulates the expression of structural genes by providing a binding site to transcription factor which in turn regulate the gene expression by altering the binding of RNA polymerase to the promoter region. A promoter is a DNA segment where transcription of a particular gene starts. The regulator genes code for transcription factor/repressor proteins that binds to operators or promoters and prevent RNA polymerase from transcribing RNA. The alteration in repressor proteins by inducers make them unable to bind DNA and allow RNA polymerase to carry out transcription. Thus regulator gene control the functioning of structural genes via operator gene. Option C is correct answer.

Gene which is responsible for the synthesis of a polypeptide chain is called as

  1. Promotor gene

  2. Structural gene

  3. Regulator gene

  4. Operator gene


Correct Option: B
Explanation:

Promoter is a DNA segment that serves to initiate transcription of a particular gene. They are present upstream near the transcription start sites of genes. Regulator gene regulates the expression of structural genes by its protein product that are mostly transcription factors. These transcription factors bind to the operator region which is located just upstream the binding site of the RNA polymerase and hence, prevent the binding and transcription. Operator is a DNA sequence present between the promoter region and the first coding gene. This operator region serves as repressor protein binding site. The gene that codes for any RNA / protein product which do not serve as regulatory protein are known as structural genes. The lac Z lac Y and lac A genes in lac operon are the structural genes. Option B is the correct answer.

Functioning of structural genes is controlled by

  1. Operator

  2. Promoter

  3. Ligase

  4. Regulator gene


Correct Option: D
Explanation:

Operon can be defined as DNA segment having a cluster of genes which are controlled by single promoter. It consists of operator gene and structural genes. The operator gene regulates the expression of structural genes by providing a binding site to transcription factor which in turn regulate the gene expression by altering the binding of RNA polymerase to the promoter region. A promoter is a DNA segment where transcription of a particular gene starts. Ligase enzymes facilitate the joining of two DNA strand together by phosphodiester bonds. The regulator genes code for transcription factor/repressor proteins that binds to operators or promoters and prevent RNA polymerase from transcribing RNA. The alteration in repressor proteins by inducers make them unable to bind DNA and allow RNA polymerase to carry out transcription. Thus regulator gene control the functioning of structural genes via operator gene. Option D is correct answer.

Which of the following hormones control gene expression?

  1. growth hormone

  2. prolactin

  3. oxytocin

  4. thyroxine


Correct Option: A
Explanation:

  • Growth hormone helps in amino acid uptake in all the tissues and also help in the transcription process in which DNA is converted into mRNA.
  • GH also help in synthesis of protein hormone.
  • It also helps to decrease protein catabolism.
Hence, the correct answer is 'Growth hormone'

A co-ordinated unit which controls the genetic expression is called as a/an

  1. Cistron

  2. Recon

  3. Operon

  4. Muton


Correct Option: C
Explanation:
Cistron: Is a section of a DNA or RNA molecule that codes for a specific polypeptide in a protein synthesis.
Recon: In a cistron, the recombinational units may be more than one. Thus, the smallest unit capable of undergoing recombination is called as a recon.
Muton: It may be defined as, "the smallest unit of DNA which may be changed is the nucleotide''. Therefore, cistron is the largest unit in size followed by recon and muton. This can be explained that a gene consists of several cistron, a cistron contains many recons and a recon contains a number of mutons. 
Operon: It is a unit of genetic material that functions in a co-ordinated manner by means of an operator, a promoter and one or more structural genes that are transcribed together.
Thus, the correct answer is option C.

Operon contains

  1. Operator and regulator genes

  2. Operator and structural genes

  3. Operator, regulator genes and repressor

  4. Operator gene, regulator gene, repressor gene, structural genes and promoter gene


Correct Option: D
Explanation:

  • Operator gene is a segment of DNA present between the promoter and the genes of the operon. It helps in transcribing the genes of the operon.
  • Regulator gene often codes for repressor proteins which bind with the operator and checks the operon.
  • Repressor gene physically obstructs the RNA polymerase from transcribing the genes by binding with the operator gene.
  • Structural genes are the genes that undergo translation to produce enzymes and are co-regulated by the operon.
  • Promoter gene is a nucleotide sequence that enables a gene to be transcribed. It is recognized by RNA polymerase, which then initiates transcription.
So, the correct option is 'Operator gene, regulator gene, repressor gene, structural genes and promoter gene'.

Which of the following is an example of positive gene regulation?

  1. The tryptophan gene, in which the presence of tryptophan functions as a corepressor to prevent its own transcription.

  2. The lac gene, in which the repressor preventing the synthesis of the enzymes that degrade lactose is deactivated by the presence of lactose.

  3. CAP, which acts as a required transcription factor for the enzymes that degrade lactose.

  4. All of the above.


Correct Option: A
Explanation:

Regulation of functioning of the expression of genes is known as the regulation of gene expression. It is basically of three types- inducible, constitutive and repressible.

The repressible kind of control is when the product of regulatory gene initiates the expression of the gene under its control.
The tryptophan consists of repressible Operon model in which when the end product tryptophan is present in sufficient amount it's molecules act as corepressor and the structural genes become switched this is also known as feedback repression or positive regulation.

So, the correct option is 'The tryptophan gene, in which the presence of tryptophan functions as a corepressor to prevent its own transcription.'

RNA polymerase which is on the promoter, moves to the structural genes to transcribe them. However, it happens when

  1. RNA polymerase shifts first to regulator gene.

  2. Inducer binds to structural genes.

  3. There is repressor on the operator.

  4. There is no repressor on the operator.


Correct Option: D
Explanation:

The promoter is a DNA segment that serves to initiate transcription of a particular gene. They are present upstream near the transcription start sites of genes. Regulator gene regulates the expression of structural genes by its protein product that is mostly transcription factors, also termed as the repressor. The operator is a DNA sequence present between the promoter region and the first coding gene. This operator region serves as a repressor protein binding site. The repressor binds to operator region which is located just upstream the binding site of the RNA polymerase and hence, prevent the binding and transcription; this makes option C incorrect. Regulator gene serves to regulate the expression of structural genes via repressor; it does not provide the binding site for RNA polymerase; option A is wrong. The inducer is a molecule that binds to repressor to prevent its binding to operator region and thereby, facilitates gene expression; option B is incorrect.

Genes that are involved in turning on or off the transcription of a set of structural genes are called as

  1. Polymorphic genes

  2. Operator genes

  3. Redundant genes

  4. Regulatory genes


Correct Option: D
Explanation:

Regulator gene regulates the expression of structural genes by its protein products that are mostly transcription factors. These transcription factors bind to the operator region which is located just upstream the binding site of the RNA polymerase and hence prevent the binding and transcription; option D is correct. Operator is a DNA sequence present between the promoter region and the first coding gene. This operator region serves as repressor protein binding site; option B is wrong. Genes which govern more or less same trait or perform same role are called redundant genes; presence of these genes confers advantage of diluting the effect of point mutation on organisms; option C is wrong. Presence of more than one allele on a genetic locus is called gene polymorphism provided that the allele is present with more than 5% frequency in the population; option A is wrong. 

A specific nucleotide sequence to which RNA polymerase attaches to initiate transcription of mRNA, is the sequence of which gene?

  1. Promoter gene

  2. Structural gene

  3. Operon

  4. Regulator gene


Correct Option: A
Explanation:

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 5' region of the sense strand).

According to the operon concept, the regulatory gene regulates the chemical reactions of the cell by

  1. Inactivating enzymes in the reaction

  2. Inhibiting transcription of mRNA

  3. Inhibiting migration of mRNA into cytoplasm

  4. Inhibiting the substrate in the reaction


Correct Option: B
Explanation:

An operon is a functioning unit of genomic DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo trans-splicing to create monocistronic mRNAs that are translated separately. Regulator gene regulates inhibiting transcription of mRNA.

Regulated unit of genetic material is termed as

  1. Operon

  2. Regulator gene

  3. Operator gene

  4. Okazaki segment


Correct Option: A

Tryptophan operon of Escherichia coli is

  1. Monocistronic

  2. Inducible

  3. Unregulated

  4. Repressible


Correct Option: D

Which is correct

  1. Both animal and plant cells have a well defined cell wall

  2. Cells are formed de novo from abiotic materials

  3. Cells of all living organisms have a nucleus

  4. In prokaryotes there are no membrane bound cell organelles.


Correct Option: D

Where are regulatory genes located?

  1. Along with the structural genes

  2. In between operator and the structural genes

  3. In the middle of structural genes

  4. Upstream of transcription sites


Correct Option: D
Explanation:

The gene that codes for any RNA/protein product which does not serve as regulatory protein is known as structural genes. The operator is a DNA sequence present between the promoter region and the first coding gene. The operator region serves as the repressor protein binding site. The promoter is a DNA segment that serves to initiate transcription of a particular gene. They are present upstream near the transcription start sites of genes in between the operator and structural gene. The regulatory gene regulates the expression of structural genes by its protein products that are mostly transcription factors. It is not the part of an operon, which means that it is present upstream or downstream the structural genes but not in between; the Regulatory gene is present upstream the operator gene. Thus, the correct answer option D.

Part of operon producing repressor is known as

  1. Repressor gene

  2. Operator gene

  3. Regulator gene

  4. Promoter gene


Correct Option: C

Genes that are involved in turning on or turning off the transcription of a set of structural genes are called as

  1. Polymorphic genes

  2. Operator genes

  3. Redundant genes

  4. Regulatory genes


Correct Option: B
Explanation:

In the operon model, the operator is the gene segment to which a repressor binds. This prevents the RNA polymerase from transcribing certain genes in the operon unit.

In lac operon model, repressor protein binds to which site?

  1. Structural genes

  2. Promotor

  3. Operator

  4. None of the above


Correct Option: C
Explanation:

Lac repressor is part of the regulatory network of the lac operon. Lac repressor controls the production of three proteins produced from the gene and affecting the metabolism of lactose. This repressor molecule is a tetramer whose all the subunits are identical. This tetramer binds to a particular region in the bacterial DNA called the operator. This region is present next the three lactose metabolizing proteins. Binding of the repressor to operator causes the block in the production of protein. Otherwise, for three genes to transcribe the repressor protein binds to the lactose molecule and hence unable to bind to operator allows the genes to transcribe.

Wild type Escherichia coli growing on medium having glucose is transferred to lactose containing medium. Which change occurs?

  1. Lac operon is induced

  2. Lac operon is suppressed

  3. All operons are induced

  4. The bacterium stops dividing


Correct Option: A

In repressible or negative operon

  1. Corepressor binds with inducer

  2. Corepressor binds with aporepressor

  3. Corepressor does not bind with repressor

  4. cAMP has negative effect


Correct Option: B

In lac-operon, repressor protein binds to

  1. Regulator gene

  2. Operator gene

  3. Promoter gene

  4. Structural gene


Correct Option: B

Operon contains

  1. Operator and regulator genes

  2. Operator and structural genes

  3. Operator and regulator genes, and repressor

  4. Operator gene, regulator gene, repressor, structural genes and promoter gene


Correct Option: D

Telomere of eucaryotic chromosome possesses short segments of

  1. Guanine rich repeats

  2. Thymine rich repeats

  3. Cytosine rich repeats

  4. Adenine rich repeats


Correct Option: A

Lac operon is

  1. Arabinose operon

  2. Repressible operon

  3. Inducible operon

  4. Overlapping genes


Correct Option: C

Eucaryotic genome differs from procaryotic genome in

  1. DNA is circular arid single-stranded in procaryotes

  2. Intervening sequences are present in eucaryotic DNA

  3. DNA is coinplexed with histones in procaryotes

  4. DNA is organised into operons in eucaryotes


Correct Option: B

Operon is

  1. Sequence of three nitrogen bases determining a single amino acid

  2. A set of closely placed genes regulating a metabolic pathway in procaryotes

  3. Segment of DNA specifying a polypeptide

  4. Gene responsible for switching on and switching off of other genes


Correct Option: B

In eukaryotes transcription occurs in

  1. Cytoplasm

  2. Nucleus

  3. Cytosol

  4. Matrix


Correct Option: B

In an inducible operon, the genes are

  1. Usually expressed unless a signal turns them "off

  2. Never expressed

  3. Always expressed

  4. Usually not expressed unless a signal turns them on


Correct Option: D

In processing of eukaryotic hnRNA during protein-synthesis tailing involvesof RNA

  1. Addition of adenylate residues at 3' end

  2. Addition of methyl guanosine triphosphate at 3' end

  3. Addition of methyl guanosine triphosphate 5' end

  4. Removal of introns


Correct Option: A

In operon model, the function of regulator gene is to produce

  1. Repressor

  2. Inducer

  3. Corepressor

  4. DNA


Correct Option: A

The enzyme peptidyl transferase of prokaryotes resides in 

  1. 50 S ribosome

  2. 30 S ribosome

  3. 40 S ribosome

  4. 60 S ribosome


Correct Option: A

Prokaryotic enzyme with 5'--> 3 exonuclease property is

  1. DNA polymerase I

  2. DNA polymerase II

  3. DNA polymerase III

  4. Both A and C


Correct Option: A

Which of the following DNA polymerase of prokarytoes have both 3' - 5' and 5' - 3' exonuclease activity

  1. DNA Pol-II

  2. DNA Pol-I

  3. DNA Pol-IV

  4. DNA Pol-III


Correct Option: B

Prokaryotes can be distinguished from eukaryotes as they lack

  1. RNA

  2. Ribosomes

  3. Gene discontinuity

  4. Unique DNA sequences


Correct Option: C

In eukaryotes, which of the following genes synthesise heterogeneous nuclear RNA 

  1. Holandric genes

  2. Split genes

  3. A-genes

  4. Z-genes


Correct Option: B

Which one of the following is NOT a component of lactose operon in bacteria?

  1. Operator

  2. Repressor

  3. Regulator

  4. Structural gene


Correct Option: A

The smallest unit of DNA capable of coding for the synthesis of a polypeptide is the ___________.

  1. Operon

  2. Promoter

  3. Cistron

  4. Replicon


Correct Option: A

In eukaryotes, removal of RNA polymerase III from nucleoplasm will affect transcription of  

  1. mRNA

  2. hnRNA

  3. tRNA

  4. 5.8 S rRNA

  5. 18 S rRNA


Correct Option: C

In Negative operon : -

  1. Inducer binds with repressor

  2. Co-repressor does not binds with repressor

  3. Corepressor binds with inducer

  4. CAMP have negative effect on lac operon


Correct Option: A
Explanation:
The inducer is a molecule that regulates gene expression. An inducer can bind to protein repressors or activators. The lac operon is a negatively controlled inducible operon, where the inducer molecule is Lactose. If the inducer molecule is present, it binds to the repressor and changes its conformation so that it is unable to bind to the operator and thus gene expression is controlled.
So, the correct answer is 'Inducer binds with repressor'.

The function of a repressor protein in an operon system is to prevent protein synthesis by binding to ________________.

  1. The ribosome

  2. The RNA polymerase, thus blocking transcription

  3. A specify region of the mRNA, preventing translation to protein

  4. A specific region of the operon, preventing transcription of structural genes


Correct Option: A

How many of the following statements are correct
(A) In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression
(B) Lac operon is under negative regulation of CAP.
(C) Presence of intron is reminiscent of antiquity.
(D) Inheritance of a character is also affected by promoter and regulatory sequence of a structural gene.

  1. $2$

  2. $3$

  3. $4$

  4. $5$


Correct Option: B

Regulator gene controls chemical synthesis(Operon concept) by.

  1. Inhibiting transcription

  2. Inhibiting enzymes

  3. Inhibiting passage of mRNA

  4. Inhibiting substrate enzyme reaction


Correct Option: A

Read the following four statements (A-D) :
(A) In transcription, adenine pairs with uracil.
(B) Regulation of lac operon by repressor is referred to as positive regulation.
(C) The human genome has approximately 50,000 genes.
(D) Haemophilia is a sex-linked recessive disease.
How many of the above statements are correct?

  1. Three

  2. Four

  3. One

  4. Two


Correct Option: D
Explanation:
A. Transcription is the process of synthesis of RNA from a template DNA by the replicative enzyme RNA polymerase. As we know, purine bases pair with pyrimidine bases i.e. Adenine pairs with Thymine or vice versa and Guanosine pairs with Cytosine or vice versa. Since RNA has Uracil instead of Thymine, Adenine pairs with Uracil in transcription. Hence, statement A is correct.
B. The regulation of lac operon by repressor is negative regulation as in the presence of repressor (lactose in case of E. coli), the transcription of the structural gene doesn't occur because repressor binds to the operator region and due to this, RNA polymerase can't proceed transcription. Hence, statement B is incorrect.
C. Human genome has approximately 30,000-40,000 genes. Hence, statement C is incorrect. 
D. Haemophilia is a sex linked disorder. It is a X-linked recessive disease which is caused by a recessive gene located on X chromosome. Hence, statement D is correct.
So, out of all statements given in the question, statements A and D are correct.
So, the correct answer is 'Two'. 

Which one of the following is wrong:

  1. $Y$ in Lac Operon is responsible for $\beta$ galactoside permease

  2. In Lac-operon the repressor becomes inactive if it binds with lactose

  3. In repressible control of gene action the repressor cannot bind to promotor if co repressor is present

  4. Tryptophan operon consists of five structural genes

  5. The mRNA produced from a bacterium is usually polycistronic


Correct Option: A

Choose the correct answer from the alternatives given :
You have created a fusion between trp operon and lac operon which encodes the enzymes for tryptophan biosynthesis, under the regulatory control of the lac operator. Under which of the following conditions will tryptophan synthase be induced in the strain that carries the chimeric operator fused operons?

  1. Only when both lactose and glucose are absent.

  2. Only when both lactose and glucose are present.

  3. Only when lactose is absent and glucose is present.

  4. Only when lactose is present and glucose is absent.


Correct Option: D
Explanation:

As the chimeric operon is under control of operator gene of lac operon, it will be functional only in the conditions required for lac operon to be functional. In lac operon lactose function as inducer hence its presence in medium is essential for proper functioning while glucose inhibits its function. So, the chimeric operon will produce tryptophan only when lactose is present and glucose is absent in the medium.

So, the correct answer is 'Only when lactose is present and glucose is absent.'.

Choose the correct answer from the alternatives given.
An operon is a

  1. Protein that suppresses gene expression

  2. Protein that accelerates gene expression

  3. Cluster of structural genes with related functions

  4. Gene that switches other genes on or off


Correct Option: C
Explanation:

An operon, in genetics, is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. The promoters are the palindromic sequences that control the process of transcription. An operon can be inducible like lac operon or it can be inhibitor operon like trp operon. 

So, the correct option is 'Cluster of structural genes with related functions'.

Choose the correct answers from the alternatives given.
The prokaryotic genetic system contains:       

  1. either DNA or histones

  2. neither DNA nor histones

  3. DNA and histones

  4. DNA but no histones


Correct Option: D
Explanation:

The prokaryotic genetic system does not have a nucleus in their cell but the genome in a prokaryote is held within a DNA in the cytosol called nucleoid.

Eukaryotes have DNA wrapped around the histones but prokaryotes do not contain histones.
Hence, the correct answer is, 'DNA but no histones'.

In Prokaryotes, the predominant site for control of gene expression is 

  1. Transcriptional intimation

  2. Processing level

  3. Transfer of mRNA from nucleus to the cytoplasm

  4. Translation initiation


Correct Option: A
Explanation:
Regulation of gene expression refers to a very broad term that may occur at various levels. In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression. 
Considering that gene expression results in the formation of a polypeptide, it can be regulated at several levels. In eukaryotes, the regulation could be exerted at
(i) transcriptional level (formation of primary transcript),
(ii) processing level (regulation of splicing),
(iii) transport of mRNA from the nucleus to the cytoplasm,
(iv) translational level.

So, the correct option is 'Transcriptional intimation'.

Choose the correct answer from the alternatives given :
Control of gene expression takes place at the level of

  1. DNA-replication

  2. Transcription

  3. Translation

  4. None of the above.


Correct Option: B,C
Explanation:

Regulation of gene expression refers to a very broad term that may occur at various levels. In eukaryotes the gene expression can be regulated at transcriptional level, processing level, transport of mRNA from nucleus to the cytoplasm, and translational level whereas in prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression.

So, the correct answer is 'Transcription and Translation'.

In an operon model, regulator gene function as

  1. Repressor

  2. Regulator

  3. Inhibitor

  4. All of the above


Correct Option: D
Explanation:

Operon model contains a cluster of genes which are under the control of single promoter. It consists of an operator, promoter, regulator and structural genes. The regulator gene function as a repressor as it produces repressor protein that binds to the operator and thus inhibits the transcription of the structural genes. It functions as regulator as it regulates the transcription of structural gene. The product of regulator gene is inhibitor that keeps the operon model turned off.

Thus, the correct answer is option D.

Match the columns and find out correct combination.

Gene Product Function of the product
I. Z-gene $\beta$-galactosidase Hydrolysis of lactose
II. y-gene Transacetylase Uptake of lactose
III. a-gene Permease protien Function not-known
IV. Inhibitor gene Repressor protien Switch off operator gene
  1. II and III

  2. I and III

  3. I, III, IV

  4. I and IV


Correct Option: D
Explanation:

I. The z gene that codes for the enzyme beta-galactosidase that hydrolyzes lactose to glucose and galactose.

IV. Inhibitor is a represser protein which switch off the process in lac operon process. 

Morphogensis is controlled by______________ 

  1. Gibberellins and Cytokinin

  2. Auxin and Cytokinin

  3. Auxin and Gibberellins

  4. Gibberellins and Zeatin


Correct Option: A
Explanation:

Morphogenesis is a process that controls the organized spatial distribution of cells during embryonic development. It can also take place in a matured organism in cell culture or in tumor cell masses. It is concerned with the shape of tissues. Plant growth regulators such as gibberellins, cytokinins, abscisic acid and ethylene control growth and development in plants. Gibberellins and cytokinins are the two instrumental hormones that play a key role in morphogenesis. Whereas auxins stimulate the plant cell to grow long.

So the correct answer is 'gibberellin and cytokinin'.

When Tryptophan is present

  1. repressor is unable to bind to the operator

  2. transcription of structural genes occurs

  3. repressor is able to bind to the operator

  4. both (a) and (b)


Correct Option: C
Explanation:

The Trp operon is an example of a repressible operon; it is on unless turned off by a repressor protein. The repressor protein is synthesized by trpR. While the repressor protein is always present in the cell, it is synthesized in an inactive form. When a corepressor is present, in this case, tryptophan, it binds to the repressor protein in an allosteric site. This changes the conformation of the protein such that it can bind to the operator and block transcription by preventing the binding of RNA polymerase to the promoter. In this way, the cell saves energy by not producing tryptophan when it is already present.

So, the correct option is 'repressor is able to bind to the operator'.

A mutation that renders the regulatory gene of a repressible operon nonfunctional would result in

  1. excessive synthesis of a catabolic activator protein

  2. irreversible binding of the repressor to the promoter

  3. inhibition of transcription of the structural genes

  4. continuous transcription of the structural genes


Correct Option: D
Explanation:

In a repressible operon, the operon is normally on and transcription occurs for the synthesis of enzymes. This synthesis of enzymes takes place with the help of the structural genes.

In presence of corepressor (for e.g. tryptophan in trp operon) inactive repressor (aporepressor) gets converted to the active repressor. This active repressor binds to operator region and stops transcription. If any mutation takes place in regulatory genes i.e. those involved in the formation of operator and repressor, operon will never get turned off. This will result in continuous transcription of the structural genes. 
So, the correct option is 'continuous transcription of the structural genes'.

Inducible operons differ from repressible operons in that

  1. operator of inducible operons is switched off by a repressor protein

  2. inducible operons have an operator that controls binding of RNA polymerase to the promoter region

  3. inducible operons use activators and positive control to regulate their transcription

  4. inducible operons usually include structural genes that function in catabolic pathways


Correct Option: D
Explanation:

The inducible operon is usually off and it can be induced in the presence of inducer like lactose. After getting induced, the operon is turned on and transcription takes place to catabolize these inducers. Hence, the inducible operon is usually involved in catabolism. 

While repressible operon is on normally and results in transcription of structural genes to produce the desired product for e.g. tryptophan. Hence, it works at times when the bacterial cell does not require these products like tryptophan and the presence of tryptophan from external source turns off this operon. 
So, the correct option is 'inducible operons usually include structural genes that function in catabolic pathways'.

Choose the correct answer from the alternatives given :
Repressible operon system is usually found in (i) pathways. The pathways end product serves as a (ii) to activate the repressor, turn off enzyme synthesis and prevent overproduction of the end product of the pathway. Genes for this operon are usually switched (iii) and the repressor is synthesised in an (iv) form.

  1. (i) anabolic, (ii) corepressor, (iii) on, (iv) - inactive

  2. (i) anabolic, (ii) inducer, (iii) off, (iv) - active

  3. (i) catabolic, (ii) inducer, (iii) off, (iv) - active

  4. (i) catabolic, (ii) corepressor, (iii) on, (iv) - inactive


Correct Option: A
Explanation:

Repressible operons are generally involved in anabolic pathways, or the synthesis of an essential component, while inducible operons are generally involved in catabolic pathways or the breakdown of a nutrient. Positive control of an operon is when gene expression is stimulated by the presence of a regulatory protein. The repressible operon work on the feedback inhibition mechanism which is the phenomenon where the output of a process is used as an input to control the behavior of the process itself and the co-repressor serves as to activate the repressor. Genes of a repressible operon are switched off as they are required to synthesize the structural/functional genes in the absence of the repressor. The presence of the repressor can stop this process and hence the repressor is present in the inactive form. 

So, the correct option is '(i) anabolic, (ii) corepressor, (iii) on, (iv) - inactive'.

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