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Platelets and their function - class-XI

Description: platelets and their function
Number of Questions: 56
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Tags: human physiology transport in animals blood circulatory system of human the circulatory system biology body fluids and circulation
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Platelets are

  1. Source of growth factors

  2. Involved in hemostasis

  3. Lead to blood clots

  4. All of the above


Correct Option: D
Explanation:

Platelets are parts of the blood that help the blood clot. They are smaller than red or white blood cells. Platelets are a natural source of growth factors. They circulate in the blood of mammals and are involved in hemostasis, leading to the formation of blood clots. Platelets release thread-like fibers to form these clots. 

Therefore, the correct answer is option D.

The process of blood clotting does not require

  1. Sodium ions

  2. Calcium ions

  3. Prothrombin

  4. Vitamin K

  5. Platelets


Correct Option: A
Explanation:

Blood clotting is the process by which blood changes from liquid to gel and stop bleeding. When the blood vessels get injured, platelets in blood produces prothrombin in the presence of vitamin K. The prothrombin then converts into the thrombin (active form) in the presence of thrombokinase and calcium ions. This thrombin then converts fibrinogen (inactive) into the fibrin (active). Fibrin thread then plugs the damaged part and appear like a clot. Thus, the correct answer is option A.

Name of cells which help in clotting of blood in mammals ____________.

  1. Platelets

  2. Thrombocytes

  3. Lymphocytes

  4. Monocytes


Correct Option: A
Explanation:

Platelet, also called thrombocyte, colourless, nonnucleated blood component that is important in the formation of blood clots (coagulation). Platelets are found only in the blood of mammals.


So, the correct answer is 'Platelets'.

Blood platelets occur in the blood of ____________.

  1. Birds

  2. Mammals

  3. Reptiles

  4. Amphibians


Correct Option: B
Explanation:

Only mammals have platelets, tiny cells without nuclei that are responsible for plugging the leaks in the blood vessels. Other animals use more conventional systems of hemostasis. Some marine invertebrates have a single type of blood cell, responsible for hemostasis, but also for other types of defences. Non-mammalian vertebrates have specialized nucleated thrombocytes to do the job.


So, the correct answer is 'Mammals'.

Blood platelets are.

  1. Nucleated cells

  2. Non-nucleated cells

  3. Non-nucleated cell fragments

  4. Nucleated cell fragments


Correct Option: C
Explanation:

Platelets are small, non-nucleated cells that are derived from megakaryocytes in the bone marrow. Platelets circulate in the blood, sense damage to a blood vessel and accumulate at these sites, where they initiate blood clotting. They are fragments of cytoplasm that are derived from the megakaryocytes of the bone marrow.


So, the correct answer is 'Non-nucleated cell fragments'.

Instead of platelets, the non-mammals possess clotting factor in.

  1. Nucleated cells called thrombocytes

  2. RBC

  3. WBC

  4. Plasma


Correct Option: A
Explanation:

Only mammals have Platelets. Non-mammals possess thrombocytes which are nucleated cells which have been shown to have a haemostatic function paralleling that of mammalian platelets.


So, the correct answer is 'Nucleated cells called thrombocytes'.

Megakaryocytes.

  1. Produce leucocytes

  2. Form blood platelets

  3. Are called bone cells

  4. Are carriers of oxygen


Correct Option: B
Explanation:

A megakaryocyte is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.


So, the correct answer is 'Form blood platelets'.

The life span of thrombocytes is

  1. 4 to 5 weeks

  2. 3 to 4 weeks

  3. 3 to 7 days

  4. None of these


Correct Option: C
Explanation:
The average life span of circulating platelets is 8 to 9 days. Life span of individual 3 to 7 days thrombocytes is controlled by the internal apoptotic regulating pathway, which has a Bcl-xL timer. Old thrombocytes are destroyed by phagocytosis in the spleen and liver. So, the correct answer is "3 to 7 days.'

$1$ li. of oxygenated blood can deliver how much amount of $O _2$ to the tissue under normal conditions.

  1. $4$ ml

  2. $50$ ml

  3. $20$ ml

  4. $159$ ml


Correct Option: A

Ornithine cycle helps to remove _______ from blood.

  1. Urea

  2. $NH _3$

  3. Uric acid

  4. Arginine


Correct Option: A

What is the life span of thrombocytes?

  1. 7 - 10 days

  2. 3 - 4 weeks

  3. 2 - 5 weeks

  4. None of the above


Correct Option: A
Explanation:

Platelets, also called thrombocytes, are blood cells whose function is to stop bleeding. The average life span of circulating platelets is 7 to 10 days.

Smallest blood cells are

  1. RBC

  2. WBC

  3. Platelets

  4. None of the above


Correct Option: C
Explanation:

Platelets, also called thrombocytes, are blood cells whose function is to stop bleeding. Platelets have no nucleus: they are fragments of cytoplasm, which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid structures. They are smallest of the three major blood types. They make up a tiny portion of the blood volume.

Life span of platelet is

  1. 8 - 9 days

  2. 9 - 12 days

  3. 20 - 30 days

  4. 90 days


Correct Option: A
Explanation:

Life span of platelets is 8 - 9 days. Platelets, also called thrombocytes, are blood cells, whose function is to stop bleeding. Platelets have no nucleus: they are fragments of cytoplasm, which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid structures. Life span of individual platelets is controlled by the internal apoptotic regulating pathway. Old platelets are destroyed by phagocytosis in the spleen and liver.

Blood platelets are found in

  1. Pisces

  2. Reptiles

  3. Birds

  4. Mammals


Correct Option: D
Explanation:

Blood platelets are found in mammals. Platelets, also called thrombocytes, are blood cells, whose function is to stop bleeding. Platelets have no nucleus: they are fragments of cytoplasm, which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid structures.

Megakaryocyte cell is

  1. RBC producer

  2. Thrombocyte producer

  3. WBC producer

  4. Protein producer


Correct Option: B
Explanation:

Megakaryocytes cells is thrombocyte producer. A megakaryocyte is a large bone marrow cell with a lobulated nucleus responsible for the production of blood thrombocytes, which are necessary for normal blood clotting. Megakaryocytes normally account for 1 out of 10,000 bone marrow cells but can increase in number nearly 10- fold during the course of certain diseases.

Platelets are a source of

  1. Fibrinogen

  2. Calcium

  3. Thromoboplastin

  4. Heamoglobin


Correct Option: C
Explanation:

Platelets are a source of thromboplastin. Thromboplastin is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin. It is a complex enzyme that is found in the brain, lung, and other tissues and especially in blood platelets and that functions in the conversion of prothrombin to thrombin in the clotting of blood, called as thrombokinase.

Structure absent from fresh frozen blood plasma is

  1. Immunoglobulin

  2. Plasma

  3. Albumin

  4. Platelet


Correct Option: D
Explanation:

Structure absent from fresh frozen blood plasma are platelets. Platelets have no nucleus: they are fragments of cytoplasm which are derived from the megakaryocytes. The main function of platelets is to contribute to hemostasis: the process of stopping bleeding at the site of interrupted endothelium. They gather at the site and unless the interruption is physically too large, they plug the hole. In the fresh frozen blood plasma, there will be an absence of blood cells. So, in frozen plasma platelets are also absent.

Blood platelets are found only in the blood of

  1. Birds

  2. Reptiles

  3. Mammals

  4. Amphibians


Correct Option: C
Explanation:

Platelet also known as thrombocyte is a colourless, nonnucleated blood cell that is important in the formation of blood clots (coagulation). Platelets are found only in the blood of mammals. Platelets are formed when cytoplasmic fragments of megakaryocytes, which are very large cells in the bone marrow, pinch off into the circulation as they age. They are stored in the spleen. Hence, option C is the correct answer. 

Megakaryocytes

  1. Produce leucocytes

  2. Forms blood platelets

  3. Forms germ cells

  4. Are carriers of oxygen


Correct Option: B
Explanation:

A megakaryocyte is a large bone marrow cell with a lobulated nucleus, responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting. Megakaryocytes normally account for 1 out of 10,000 bone marrow cells but can increase in number nearly 10-fold during the course of certain diseases.

The solid part of blood is

  1. Plasma

  2. Red blood corpuscles

  3. White blood corpuscles

  4. Red, white corpuscles and platelets


Correct Option: D
Explanation:

Blood is living tissue which is made up of liquid and solids. The liquid part, called as plasma, is made of water, salts, and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells, and platelets. Red blood cells deliver oxygen from your lungs to your tissues and organs. White blood cells fight infection and are part of your body's defense system. Platelets help blood to clot when you have a cut or wound. Bone marrow, the spongy material inside your bones, makes new blood cells. Blood cells constantly die and your body makes new ones. Red blood cells live about 120 days, and platelets live about 6 days. Some white blood cells live less than a day, but others live much longer. 

Therefore, the correct answer is option D.

Which one of the following is wrong?

  1. White blood cells or leucocytes are considered as 'soldiers' of the body.

  2. Antibodies are product by the stem cells of bone marrow.

  3. Calcium ions in blood play an important role in blood clot formation.

  4. Blood platelets are cell fragments, devoid of nuclei and participate in the coagulation of blood.


Correct Option: B
Explanation:

An antibody is a large, Y-shaped protein produced by the plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. The antibody recognizes a unique molecule of the harmful agent (antigen), via the variable region. They are not formed by the stem cells. All the other statements are correct.
Therefore, the correct answer is option B.

Blood clot inside a blood vessel is called as

  1. Thrombosis

  2. Agglutinin

  3. Clot

  4. Thrombus


Correct Option: D
Explanation:

The blood clot formed inside the blood vessel is called as a thrombus. When this thrombus breaks and travels to different parts of the body, then it is called embolus. Agglutinin is responsible for the agglutination.

Hence, the correct answer is 'Thrombus'

Which of the following cells has a lifespan of 5-9 days?

  1. WBC

  2. Platelets

  3. RBC

  4. None of the above


Correct Option: B
Explanation:

The platelets are formed by fragmenting from cells found in bone marrow called as megakaryocytes, and similar to red blood cells, they do not have a nucleus. The average lifespan of a platelet is normally just 5 to 9 days.  

Therefore, the correct answer is option B.

Which of the following blood cells help in blood coagulation?

  1. RBCs

  2. Lymphocytes

  3. Thrombocytes

  4. Basophils


Correct Option: C
Explanation:

Red blood cells or RBCs are the most common type of blood cell and contains hemoglobin, which is the principal means of delivering oxygen.
Lymphocyte is a type of white blood cell, that is important in the immune system.
Basophils are granulocytes i.e., they contain large cytoplasmic granules in the cell nucleus and it stores histamine (a vasodilator).
Thrombocyte is a platelet and is crucial for blood clotting.
Thus, the correct answer is option (C), 'Thrombocytes'.

Formation of platelets is known as

  1. Haemopoiesis

  2. Thrombopoiesis

  3. Haemolysis

  4. None of the above


Correct Option: B
Explanation:

Platelets or thrombocytes are cell fragments produced from megakaryocytes (special cells in the bone marrow). Formation of platelets by fragmentation of megakaryocytes in bone marrow is known as thrombopoiesis.

So, the correct answer is 'Thrombopoiesis'.

Blood platelets are present in the blood of

  1. Fishes

  2. Amphibians

  3. Reptiles

  4. Mammals


Correct Option: D
Explanation:

The blood cells are of three major types they are erythrocytes(RBC), leucocytes(WBC) and platelets. Platelets or thrombocytes are cell fragments produced from megakaryocytes (special cells in the bone marrow).Blood normally contains 1,500,00 - 3,500,00 platelets mm – 3. Platelets can release a variety of substances most of which are involved in the coagulation or clotting of blood.  Blood platelets are present in the blood of Mammals.

So, the correct answer is 'Mammals'.

Blood platelets are

  1. Nucleated

  2. Nucleus is many lobed

  3. Nucleus is very small

  4. Denucleated


Correct Option: D
Explanation:

The blood cells are of three major types they are erythrocytes(RBC), leucocytes(WBC) and platelets. Platelets or thrombocytes are cell fragments produced from megakaryocytes (special cells in the bone marrow). Formation of platelets by fragmentation of megakaryocytes in bone marrow is known as thrombopoiesis. As blood platelets are cell fragments they do not have any nucleus i.e Denucleated.

So, the correct answer is 'Denucleated'.

Haemorrhagic disorder occurs when the platelet count falls to less than ________________.

  1. $1,50,000/mm^3$

  2. $1,00,000/mm^3$

  3. $75,000/mm^3$

  4. $50,000/mm^3$


Correct Option: D
Explanation:

Hemorrhagic Disorders Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels. Platelets play an important role in blood clotting, so thrombocytopenia puts you at higher risk of bleeding. Any time your platelet count drops below 50,000 per mm3 you are considered to be at increased risk for bleeding.


So, the correct answer is '50,000/mm3'.

Which of the following blood cells help in blood coagulation?

  1. RBCs

  2. Lymphocytes

  3. Thrombocytes

  4. Basophils


Correct Option: C
Explanation:

Thrombocytes are pieces of very large cells in the bone marrow called megakaryocytes. They help form blood clots to slow or stop bleeding and to help wounds heal.


So, the correct answer is 'Thrombocytes'.

What is correct about the statements?
Statement A. Blood sugar level falls rapidly after hepatectomy
Statement B. Glycogen of liver is principal source of blood sugar

  1. Statement A and B correct with B being reason for A

  2. Statement A is correct but B is wrong

  3. Statement A is wrong but B is correct

  4. Both correct but B is not reason of A


Correct Option: B

Thromboplastin is produced by

  1. Damaged tissues

  2. Blood platelets

  3. Both blood platelets and damaged tissues

  4. Prothrombin.


Correct Option: C

Blood platelets produce

  1. Fibrinogen

  2. Thromboplastin

  3. Haemoglobin

  4. Calcium.


Correct Option: B

Thrombocytes have a life of

  1. 3-4 weeks

  2. 4-5 weeks

  3. 5-9 days

  4. None of the above.


Correct Option: C

Platelets are given in case of

  1. Anaemia

  2. Polycythemia

  3. Thrombocytopenia

  4. Leukemia.


Correct Option: C

Cell fragments of megakaryotes yield

  1. Erythrocytes

  2. Granulocytes

  3. Agranularcytes

  4. Blood platelets/thrombocytes.


Correct Option: D

Interstitial fluid resembles

  1. Fresh water

  2. Ground water

  3. Sea water

  4. None of the above.


Correct Option: B

Which does not play any role in blood clotting according to Best and Taylor

  1. Fibrinogen

  2. Platelets

  3. Calcium

  4. Prothrombin.


Correct Option: B

Life span of blood platelets is

  1. 1 - 2 days

  2. 2 - 3 days

  3. 3 - 4 days

  4. 5 - 9 days.


Correct Option: D

Which one takes part in blood clotting

  1. RBC

  2. WBC

  3. Thrombocytes

  4. Lymphocytes.


Correct Option: C

Thromboplastin required for blood clotting at the place of injury is released by

  1. Blood platelets

  2. Eosinophils

  3. Neutrophils

  4. Lymphocytes.


Correct Option: A

Name the blood cells whose reduction in number can cause clotting disorder, leading to excessive loss of blood from the body

  1. Thrombocytes

  2. Erythrocytes

  3. Leucocytes

  4. Neutrophils.


Correct Option: A

Name the blood cells, whose reduction in number can cause clotting disorder, leading to excessive loss of blood from the body

  1. Erythrocytes

  2. Leucocytes

  3. Neutrophills

  4. Thrombocytes


Correct Option: D
Explanation:

Thrombocytes are also called Platelets. They are the vital component of blood. It's basic function is to stop bleeding by clumping and clotting blood vessel injuries. Its main function is to contribute to hemostasis that is the process of stop bleeding by adhesion. Reduction in the number of platelets causes clotting disorder and thus loss of blood from the body.

Hence, the correct option is D.

How many of the following nutrients, follow fol-lowing route of absorption
Blood capillaries $\rightarrow$ Mesentric vein $\rightarrow$ Hepatic portal vein $\rightarrow$ Liver $\rightarrow$ Hepatic vein $\rightarrow$ IVC $\rightarrow$ Heart $\rightarrow$ Body
(i) Glucose
(ii) Galactose
(iii) Fructose
(iv) L-amino acids
(v) D-amino acids
(vi) Long chain fatty acids.

  1. Six

  2. Five

  3. Only one

  4. Three.


Correct Option: A

What will happen if platelets were absent in the blood?

  1. The process of clotting will be affected.

  2. Kwashiorkor will be the result.

  3. RBC will be ruptured.

  4. The blood will become more liquid.


Correct Option: A
Explanation:

Platelets are the colourless cell fragments present in the blood. They are involved in the clotting. In the absence of platelets, the process of clotting will be affected. If there will be any wound when platelets are absent, the animal will die by shredding of all the blood.

Therefore, the correct answer is option A.

One of the common symptoms observed in people infected with dengue fever is

  1. Significant decrease in RBC count

  2. Significant decrease in WBC count

  3. Significant decrease in platelets count

  4. Significant increase in platelets count


Correct Option: C
Explanation:
Dengue is a type of fever caused by the dengue virus and propagated by mosquitoes. A significant decrease in the number of platelets is observed in this disease.
Thus, the correct answer 'Significant decrease in platelets count.'

Identity the wrongly matched pairs 

  1. Monocyte - Actively phagocytic

  2. Thrombocyte - Produces antibodies

  3. Lymphocyte - Initiates blood clotting

  4. Eosinophil - Associated with allergy


Correct Option: B
Explanation:

Monocytes are actively phagocytic and they take in the invading pathogen or cell through the method of phagocytosis.

thrombocytes are also known as platelet and the main function is in blood clotting. They do not produce any antibodies.
Lymphocytes have to play an important role in the immune system as well as blood clotting. 
Eosinophil cells are also responsible for immunity and are associated with allergic reactions in the body caused due to allergents as well as some infections.
So the correct answer is ' Thrombocyte- Produces antibodies'.

Platelets are formed by .....P ..... of special cells in ....Q.......

  1. P - Division , Q - Bone Marrow

  2. P - Division , Q - Lymph nodes

  3. P - Fragmentation , Q - Bone Marrow

  4. P - Fragmentation , Q - Lymph nodes


Correct Option: C
Explanation:

Platelets are formed by the fragmentation of special cells named megakaryocytes in bone marrow cell so answer is option.        

 C. P- FRAGMENTATION , Q - Bone marrow

Megakaryocyte forms

  1. Leucocytes

  2. Erythrocytes

  3. Monocytes

  4. Thrombocytes


Correct Option: D
Explanation:

A megakaryocyte is a large bone marrow cell with a lobulated nucleus, responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting. 

Critical count of platelet is

  1. 40, 000 / mm$^3$

  2. 1 lac / mm$^3$

  3. 2 lac / mm$^3$

  4. 4 lac / mm$^3$


Correct Option: A
Explanation:

Critical count of platelet is 40, 000 / mm$^{3}$. Platelets, also called thrombocytes, are blood cells whose function is to stop bleeding. Platelets have no nucleus: they are fragments of cytoplasm, which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid structures. The normal number of platelets in the blood is 150,000 - 400,000 platelets per microliter (mcL). A low platelet count is below 150,000. If the platelet count is below 50,000, the risk of bleeding is very high. So, it is called critical platelet count.

Life span of blood platelets in mammals is about

  1. 3 days

  2. 8 days

  3. 1 month

  4. 20 days


Correct Option: B
Explanation:
Platelets are the smallest of the three major types of blood cells. Platelets are anuclear cytoplasmic fragments essential for blood clotting and wound healing. Blood platelets begin their lives as hematocytoblasts, or stem cells. Blood platelets have a life span of 8-10 days, at the end of which they undergo programmed cell death or apoptosis.
Hence, answer is '8 days'.

Which of the following results from cell fragmentation?

  1. RBC

  2. WBC

  3. Plasma

  4. Platelets


Correct Option: D
Explanation:

Platelets are the cells found in blood which helps in the clotting of the blood. The formation of platelets takes place in bone marrow from large bone marrow cells known as megakaryocytes. These cells after becoming mature enough, undergo the process of cell fragmentation to produce platelet cells. The hormone that help in platelet production is thrombopoietin. 

So, the correct answer is D.

Low platelet count results in

  1. Low bleeding

  2. Excessive bleeding

  3. Growth

  4. Both B and C


Correct Option: B
Explanation:

Platelets are the parts of the blood that help the blood clot. They are smaller than red or white blood cells. If the number of platelets is too low, excessive bleeding can occur. However, if the number of platelets is too high, blood clots can form thrombosis, which may obstruct blood vessels and result in such events as a stroke. 

Therefore, the correct answer is option B.

With reference to the blood in a normal person, which one of the following statements is correct?

  1. Compared to arteries, veins are less numerous and hold less of the body's blood at any given time.

  2. Blood cells constitute about 70 percent of the total volume of the blood.

  3. White blood cells (WBC) are made by lymph nodes only.

  4. The blood has more platelets than WBC.


Correct Option: D
Explanation:
Blood is a specialized body fluid. It has four main components: plasma, red blood cells, white blood cells and platelets. The blood has more platelets than WBC. A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. An average normal range for white blood cells is between 4,500 and 10,000 /mcl.
Blood has many different functions. They are as follows:
  • Transporting oxygen and nutrients to the lungs and tissues.
  • Forming blood clots to prevent excess blood loss.
  • Carrying cells and antibodies that fight infection.
  • Bringing waste products to the kidneys and liver, which filter and clean the blood.
  • Regulating body temperature.

Megakaryocytes, special cells in the bone marrow that produce cell fragments are called :

  1. Leucocytes

  2. Erythrocytes

  3. Thrombocytes

  4. Fibrinogen


Correct Option: C
Explanation:

Megakaryocyte is a large bone marrow cell which are responsible for the production of thrombocytes. Thrombocytes help in normal blood clotting.

Hence, he correct option is C.

Select the incorrectly matched pair.

  1. Leukopenia - Fall in WBCs count

  2. Polycythemia - Abnormal rise in RBCs count

  3. Thrombocytosis - Decrease in number of platelets

  4. Erythrocytopenia - Decrease in number of RBCs


Correct Option: C
Explanation:

(a) Leukopenia is the decrease in the white blood cell count in the cells. 

(b) Polycythemia is a state in which the percentage of red blood cells in our body is elevated. 
(c) Thrombocytosis is the condition in which there is an excessive number of platelets in the blood cell.
(d) Erythrocytopenia-  It is a state in which there is a deficiency of Red blood cells in our body.
So, the correct option is 'Thrombocytosis- Decrease in a number of platelets'.

Tooth extraction in a person causes death due to excessive bleeding. This is because of

  1. Absence of prothrombin

  2. Presence of plasma factor that causes haemorrhage

  3. Presence of plasma factor that prevents blood clotting

  4. Absence of plasma factor required for haemorrhage


Correct Option: A
Explanation:

Prothrombin is a glycoprotein occurring in blood plasma and is an essential component of the blood-clotting mechanism. Prothrombin is transformed into thrombin by a clotting factor known as factor X or prothrombinase; thrombin then acts to transform fibrinogen, also present in plasma, into fibrin, which, in combination with platelets from the blood, forms a clot (coagulation). Under normal circumstances, prothrombin is changed into thrombin only when an injury occurs to the tissues or circulatory system or both; therefore, fibrin and blood clots are not formed except in response to bleeding. Hypoprothrombinemia, a deficiency in prothrombin, is characterized by a tendency to prolonged bleeding. It is usually associated with a lack of vitamin K, which is necessary for the synthesis of prothrombin in the liver cells. 

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