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Antibodies and antitoxin - class-XII

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People administered with preformed antibodies get

  1. active immunity

  2. innate immunity

  3. natural immunity

  4. passive immunity


Correct Option: A
Explanation:

The immune system, which is made up of special cells, proteins, tissues, and organs, defends people against germs and microorganisms every day. In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and substances that invade body systems and cause disease.  antibodies can activate a group of proteins called complement that are also part of the immune system. Complement assists in killing bacteria, viruses, or infected cells. All of these specialized cells and parts of the immune system offer the body protection against disease. This protection is called immunity.

So the correct option is 'active immunity'.

Chemically, an antibody is a

  1. Protein

  2. Lipoprotein

  3. Lipid

  4. Nucleoprotein


Correct Option: A
Explanation:

An antibody, also known as an immunoglobulin is a large, Y-shaped protein which is produced mainly by plasma cells and it is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies are secreted by B lymphocytes of the adaptive immune system, mostly by differentiated B cells called plasma cells. Hence, chemically, an antibody is a protein.

So, the correct answer is 'Protein'.

Lysis of foreign cells is mediated through

  1. IgM only

  2. IgA only

  3. IgM and IgG

  4. IgD and IgE


Correct Option: C
Explanation:
  • Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. IgM can bind to complement component and activate the classical pathway, leading to opsonization of antigens and cytolysis (lysis of foreign cells).
  • IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Coating of IgG on pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the lysis of foreign cells.
So, the correct answer is 'IgM and IgG'.

Antibodies are formed by

  1. T-cells

  2. Monocytes

  3. Phagocytes

  4. B-cells


Correct Option: D
Explanation:

Antibody are produced by B-lymphocytes. The plasma cell /plasma B cells/effector B cell are white blood cells that secrete large volumes of antibodies. Plasma cell originates in the bone marrow.B cell differentiate into a plasma cell that produces antibody molecules. These are transported by the blood plasma and the lymphatic system. Once these are released into the blood and lymph, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.

So, the correct answer is 'B-cells'.

Antibodies are complex 

  1. Lipoproteins

  2. Steroids

  3. Prostaglandins

  4. Glycoproteins


Correct Option: D
Explanation:

Immunoglobulin also known as antibodies are glycoprotein molecules produced by plasma cells (white blood cells). They act as a critical part of the immune response by specifically recognizing and binding to particular antigens, such as bacteria or viruses and help in their destruction.The antibody immune response is highly complex and exceedingly specific. Hence, antibodies are complex glycoproteins.

So,the correct answer is 'Glycoproteins'.

Antibodies belong to which class of proteins?
  1. Structural

  2. Transport

  3. Immunoglobulin

  4. Enzymatic


Correct Option: C
Explanation:

An antibody which belongs to the class of immunoglobulin is a large, Y-shaped protein which is produced mainly by plasma cells and it is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies are secreted by B lymphocytes of the adaptive immune system, mostly by differentiated B cells called plasma cells. 

So, the correct answer is 'Immunoglobulin'.

Immunoglobulins (antibodies) are basically

  1. Lipoproteins

  2. Phospholipids

  3. Glycoproteins

  4. Nucleoproteins


Correct Option: A
Explanation:

Immunoglobulins, also known as antibodies, are glycoprotein molecules produced by plasma cells (white blood cells). They act as a critical part of the immune response by specifically recognising and binding to particular antigens, such as bacteria or viruses, and aiding in their destruction. So, the correct option is 'Glycoproteins'

Protein released by the host cell in response to attack by a virus is known as 

  1. Antibody

  2. Antigen

  3. Interferon

  4. Immunoglobulin


Correct Option: A
Explanation:

Antibodies (also called immunoglobulins) are large proteins. They are found in the blood or other body fluids of vertebrates. Antibodies are the key element in the adaptive immune system. The antibody recognizes a unique part of the foreign target called an antigen. It is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibody is produced by plasma cells. Antibodies can occur in two physical forms, a soluble form that is secreted from the cell to be free in the blood plasma, and a membrane-bound form that is attached to the surface of a B cell and is referred to as the B-cell receptor (BCR). 

So the correct option is 'Antibody'

Allergens are 

  1. Infectious and increased secretion of IgE

  2. Non- infectious and increased secretions of IgE

  3. Infectious and increased secretion of IgG

  4. Non- infectious and increased secretion of IgM


Correct Option: B
Explanation:
An allergen is a usually harmless substance capable of triggering a response that starts in the immune system and results in an allergic reaction. 
IgE is an immunoglobulin that plays a central role in acute allergic reactions and chronic inflammatory allergic diseases.
Human allergy is caused by a limited number of inhaled small-protein allergens that reproducibly elicit IgE production in susceptible individuals.
So the answer is option B '  Non- infectious and increased secretions of IgE'. 

Body's defence system produces antibiotics.

  1. True

  2. False


Correct Option: B
Explanation:
  • Body's defence system produces antibodies.
  • Antibodies are produced when an allergen or a foreign substance enters the human body by the immune system.
  • It protects the body from unwanted foreign particles which enter the body.
  • So, the correct answer is 'False'.

Which statement is correct?

  1. Antibodies are formed by mast cells

  2. B-lymphocytes are matured in thymus

  3. Histamine acts as inflamatory mediator

  4. CMI is mediated by B-lymphocytes


Correct Option: A
Explanation:

Mast cells are coated with IgE, which is produced by plasma cells (the antibody-producing cells of the immune system). IgE antibodies are typically specific to one particular antigen. In allergic reactions, mast cells remain inactive until an allergen binds to IgE already coated upon the cell.

So, the correct option is 'Antibodies are formed by mast cells'.

How many classes of immunoglobin are there in humans?

  1. $3$

  2. $4$

  3. $5$

  4. $6$


Correct Option: A

................  is associated with allergic reactions

  1. IgE

  2. IgG

  3. IgA

  4. IgM


Correct Option: A
Explanation:

Antibodies are the immunoglobulins which are produced in response to the antigen. The immunoglobulin E antibodies or IgE binds to an allergen and trigger the release of inflammatory chemicals such as histamine.
Therefore, the correct answer is option A.

Antibody is formed by _____________.

  1. Protein

  2. Carbohydrate

  3. Nucleic acid

  4. Lipid


Correct Option: A

Select the correct statement with respect to diseases and immunisation.

  1. If due to some reason B and T-Lymphocytes are damaged, the body will not produce antibodies against a pathogen.

  2. Injection of dead or inactivated pathogens causes passive immunity.

  3. Certain protozoans have been used to mass produce hepatitis B vaccine.

  4. Injection of snake antivenom against snake bite is an example of active immunisation.


Correct Option: A
Explanation:

Clone of B-cells is called as plasma cells which produce antibodies. Helper T-cells secrete IL-2 (interleukin-2) which stimulate B cells to produce antibodies. For example iInjection of snake antivenom against snake bite that provides artificially acquired passive immunity. Thus, the correct answer is option A.

A substance produced by the host in response to an infection or foreign structure is 

  1. Antigen

  2. Toxin

  3. Hormone

  4. Antibody


Correct Option: D
Explanation:

An antibody is a type of proteinaceous substance produced by the body's immune system when it detects harmful substances called antigens. Examples of antigens include microorganisms (bacteria, fungi, parasites and viruses) and chemicals. Each type of antibody is unique and defends the body against one specific type of antigen.

Antibodies are secreted by

  1. T-lymphocytes

  2. B-lymphocytes

  3. Both A and B

  4. Natural killer cell


Correct Option: B
Explanation:

An antibody or immunoglobulin is a  proteinaceous compound produced mainly by differentiated plasma cells i.e., B lymphocytes. It is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. Thus, the correct answer is option B.

Shape of antibody is

  1. Y shaped

  2. S shaped

  3. T shaped

  4. R shaped


Correct Option: A
Explanation:
  • Antibodies are the Y-shaped proteinaceous compound. Each is made up of 2 heavy chains and 2 light chains. 
  • An antibody is made up of a variable region and a constant region, and the region that changes to various structures depending on differences in antigens is called the variable region, and the region that has a constant structure is called the constant region.

    Hence, option A is correct.

A person who has been infected with a virus in the past can be determined by the presence of

  1. Antigens

  2. Antibodies

  3. Macrophages

  4. Pathogens

  5. Natural killer cells


Correct Option: B
Explanation:

The encounter of B cell with a specific antigen activates its clonal expansion which in turn gives rise to plasma cell and memory cells.  Memory cells are the B cells (antibodies) responsible for long-term immunity and confirm the previous encounter of a person with the specific virus. Antigens are foreign substances that induce the immune system to produce antibodies. Disease-causing organisms are called as pathogens. Natural killer cells and macrophages are components of immune system. So, the correct answer is option D.

Antibodies in are complex

  1. Prostaglandins

  2. Glycoproteins

  3. Lipoproteins

  4. Steroids


Correct Option: B
Explanation:

An antibody is a protein which is produced in response to the antigen by the plasma cells. Antibodies are $\gamma$-globulin proteins that have sugar groups attached to amino acid chains. They can be classified as glycoproteins. These are y-shaped. So, the correct answer is option B.

The cells that actually release the antibodies are

  1. Helper T-cells

  2. Cytotoxic T-cells

  3. Plasma cells

  4. Memory cells


Correct Option: C
Explanation:

Plasma cells, also known as plasma B cells or plasmocytes are white blood cells that secrete large volumes of antibodies. They are transported by the blood plasma and the lymphatic system. Plasma cells are originated in the bone marrow, B cells differentiate into plasma cells that produce antibody molecules. Once released into the blood and lymph, these antibody molecules bind to the target antigen (foreign substance) and initiate its neutralization or destruction.

So, the correct answer is 'Plasma cells'.

Lysis of foreign cells is mediated through 

  1. IgM and IgG

  2. IgG and IgA

  3. IgA and IgD

  4. IgD and IgE


Correct Option: A
Explanation:

  • Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. 
  • IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. 
  • IgM can bind to complement component and activate the classical pathway, leading to opsonization of antigens and cytolysis (lysis of foreign cells).
  • IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. 
  • Coating of IgG on pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the lysis of foreign cells.
So, the correct answer is 'IgM and IgG'.

B-cells produce antibodies in response to instruction received from 

  1. Killer T-cells

  2. Suppressor T-cells

  3. Mast cells

  4. Helper T-cells


Correct Option: D
Explanation:

B cells, also known as B lymphocytes are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system by secreting antibodies. B-cells bind to an antigen, receive help from a cognate helper T cell and differentiate into a plasma cell that secretes large amounts of antibodies.

So, the correct answer is 'Helper T-cells'.

Number of antibodies produced per day during an infection can be 

  1. 2 trillion

  2. 20 trillion

  3. 200 trillion

  4. 2000 trillion


Correct Option: B

Antibodies that function in innate immunity are

  1. IgM

  2. IgE

  3. IgA

  4. IgD


Correct Option: C
Explanation:
Immunoglobulin A (IgA) is an antibody that plays a crucial role in the immune function of mucous membranes. IgA plays an important role in innate immunity which acts as an important first line of defence. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions.
So, the correct answer is 'IgA'.

Antibody formation and immunity production by globulin protein is found in 

  1. Haemoglobin of RBC's

  2. Blood platelets

  3. Plasma

  4. Cytoplasm of RBC's


Correct Option: C
Explanation:

An antibody is produced by plasma cell. This plasma cell /plasma B cells/effector B cell are white blood cells that secrete large volumes of antibodies. Plasma cell originates in the bone marrow. B cell differentiate into a plasma cell that produces antibody molecules. These are transported by the blood plasma and the lymphatic system. Once these are released into the blood and lymph, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.

So the correct answer is 'Plasma'.

Immunoglobulin that increases in number during allergy is 

  1. IgA

  2. IgE

  3. IgG

  4. IgM


Correct Option: B
Explanation:

Immunoglobulin E (IgE) is a type of antibody that has been found only in mammals. IgE is synthesised by plasma cells. IgE has an essential role in type I hypersensitivity (allergy) which includes allergic diseases, such as allergic asthma, sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis.

So, the correct answer is 'IgE'.

Antibody

  1. Induces formation of antigen

  2. Helps in the production of WBC

  3. Is formed by WBC

  4. None of the above


Correct Option: C
Explanation:

An antibody, also known as an immunoglobulin is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies are secreted by B lymphocytes of the adaptive immune system, mostly by differentiated B cells called plasma cells. Lymphocyte is a type of WBC. Hence, Antibody is formed by WBC.

So, the correct answer is 'Is formed by WBC'.

Gamma-globulins are synthesised in

  1. Lymph and lymph nodes

  2. Liver

  3. Bone marrow

  4. Kidney


Correct Option: A
Explanation:

Globulins are immune molecules that are produced by the immune system in response to the invasion of the body of agents that are perceived by the system as being foreign. Gamma globulins belong to the class of globulins. Most significant globulins are immunoglobulins. Gamma globulins are synthesized in cells of the immune system known as lymphocytes, lymph nodes, lymph and plasma cells. 

So, the correct answer is 'Lymph and lymph nodes'.

Immunoglobin found in serum (of new born) is 

  1. IgG

  2. IgA

  3. IgM

  4. IgN


Correct Option: A
Explanation:

Immunoglobulin G (IgG) is a type of antibody., representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. The primary immunoglobulin of the newborn is the maternal IgG as this is the only immunoglobulin to cross the placental barrier. Hence, IgG is the immunoglobulin which is found in the serum of newborn babies.

So, the correct answer is 'IgG'.

Binding of antigen to antibody is through

  1. Electrostatic intereactions

  2. Covalent bonds

  3. Disulphide bridges

  4. Amide formation


Correct Option: A
Explanation:

Antibodies bind antigens through weak chemical interactions, and bonding is essentially non-covalent. Electrostatic interactions, hydrogen bonds, van der Waals forces, and hydrophobic interactions are all known to be involved depending on the interaction sites.

So, the correct answer is 'Electrostatic intereactions'.

Resistance against disease is provided by 

  1. Antigens

  2. Immunoglobulins

  3. Histamine

  4. HLA proteins


Correct Option: B
Explanation:

An antibody, also known as an immunoglobulin (Ig) is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies or immunoglobulins provides resistance against disease by neutralising antigens which are responsible for the disease. Antibodies are secreted by B-lymphocytes, mostly by differentiated B cells called plasma cells.

So, the correct answer is 'Immunoglobulins'.

Which immunoglobin is the largest in size?

  1. IgA

  2. IgD

  3. IgE

  4. IgM


Correct Option: D
Explanation:

Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Spleen and plasma cells are the major sites of specific IgM production. IgM antibodies do not pass across the human placenta.

So, the correct answer is 'IgM'.

Antibodies are produced by 

  1. Histocytes

  2. Mast cells

  3. Plasma cells

  4. Fibroblasts


Correct Option: C
Explanation:

An antibody, also known as an immunoglobulin is a large, Y-shaped protein which is produced mainly by plasma cells and it is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibodies are secreted by B lymphocytes of the adaptive immune system, mostly by differentiated B cells called plasma cells. 

So, the correct answer is 'Plasma cells'.

Which one secretes antibodies?

  1. Neutrophil

  2. Eosinophil

  3. Lymphocytes

  4. Monocyte


Correct Option: C
Explanation:

Antibodies are produced by specialized white blood cells called B lymphocytes/ B-cells. When an antigen binds to the B-cell surface, it stimulates the B cell to divide and mature into a group of identical cells called a clone. The mature B cells,called plasma cells, secrete millions of antibodies into the bloodstream and lymphatic system. Hence antibodies are secreted from lymphocytes.

So, the correct answer is 'Lymphocytes'.

Which one provides immunity to digestive tract against antigens?

  1. IgG

  2. IgE

  3. IgA

  4. IgD


Correct Option: C
Explanation:

Immunoglobulin A is an antibody that plays a crucial role in the immune function of mucous membranes. The amount of IgA produced in association with mucosal membranes is greater than all other types of antibody combined. It is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in the blood. Hence it provides immunity to the digestive tract as it is made up of a mucous membrane.

So, the correct answer is 'IgA'.

The function of IgE is

  1. Mediate in allergic response

  2. Activation of B-cells

  3. Protection from inhaled and ingested pathogen

  4. Stimulation of complement system, passive immunity to foetus

  5. present on lymphocytes surface as receptors


Correct Option: A
Explanation:

Immunoglobulin E (IgE) is a type of antibody that has only been found in mammals. IgE is synthesised by plasma cells. It plays an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, rhinitis etc. It also plays a pivotal role in responses to allergens, such as anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy.

So, the correct answer is 'Mediate in allergic response'.

Antibodies are synthesised by 

  1. B-lymphocyes

  2. Helper T-cells

  3. T-lymphocytes

  4. Memory cells


Correct Option: A
Explanation:

An antibody is produced by plasma cell. The B-Lymphocytes are white blood cells that secrete large volumes of antibodies. Plasma cell originates in the bone marrow. B cell differentiate into a plasma cell that produces antibody molecules. These are transported by the blood plasma and the lymphatic system. Once these are released into the blood and lymph, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.

So, the correct answer is 'B-lymphocytes'.

Antibody formed of five immunoglobin units /pentamer is 

  1. IgG

  2. IgM

  3. IgA

  4. IgD


Correct Option: B
Explanation:

Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. IgM is the largest antibody and it is the first antibody to appear in the response to initial exposure to an antigen. On the basis of its sedimentation velocity and appearance in electron micrographs, it was inferred that IgM is mostly a pentamer i.e., a polymer composed of five monomers.

So, the correct answer is 'IgM'.

Which of the following is involved in allergic reaction?

  1. IgA and mast cells

  2. IgG and basophils

  3. IgE and mast cells

  4. IgG and mast cells


Correct Option: D
Explanation:
  • In response to an allergy, IgE is secreted and circulates in the blood and binds to an IgE-specific receptor on the surface of other kinds of immune cells called mast cells and basophils, which are both involved in the acute inflammatory response.
  •  The IgE-coated cells, at this stage, are sensitized to the allergen. 
  • Hence, IgG and mast cells are involved in an allergic reaction.
  • So, the correct answer is 'IgG and mast cells'.

Immunoglobulin abundant in colostrum is 

  1. IgG

  2. IgA

  3. IgM

  4. IgE

  5. IgD


Correct Option: B
Explanation:
  • Immunoglobulin A (IgA) is an antibody that plays a crucial role in the immune function of mucous membranes.
  • Colostrum is a milky fluid that comes from the breasts of humans, cows, and other mammals the first few days after giving birth before true milk appears.
  • Immunoglobulin abundant in colostrum is IgA in the form of secretory IgA or sIgA. Much of these are produced by plasma cells in the mammary tissue.
  • So, the correct answer is 'IgA'.

Which antibody is first to be released in to blood following an infection

  1. IgD

  2. IgG

  3. IgM

  4. IgA


Correct Option: C
Explanation:

Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. IgM is the largest antibody and it is the first antibody to appear in the response to initial exposure to an antigen in the blood. IgM antibodies appear early in the course of an infection and usually reappear to a lesser extent after further exposure to the same antigen. IgM antibodies do not pass across the human placenta.

So, the correct answer is 'IgM'

In our body, antibodies are formed against pathogens in

  1. liver by RBCs

  2. blood by platelets

  3. thymus by lymphocytes

  4. brain by macrophages


Correct Option: C
Explanation:

The thymus gland, despite containing glandular tissue and producing several hormones, is much more closely associated with the immune system than with the endocrine system. The thymus serves a vital role in the training and development of T-lymphocytes or T cells, an extremely important type of white blood cell. T cells defend the body from potentially deadly pathogens such as bacteria, viruses, and fungi. The function of the thymus is to receive immature T cells that are produced in the red bone marrow and train them into functional, mature T cells that attack only foreign cells. T cells first reside within the cortex of the thymus where they come in contact with epithelial cells presenting various antigens. The immature T cells that respond to the antigens corresponding to foreign cells are selected to survive, mature, and migrate to the medulla while the rest die via apoptosis and are cleaned up by macrophages.


So, the correct option is 'Option C'.

The classical pathway of complement is activated by?

  1. Only antibody

  2. Only antigen

  3. Ag-antibody complex

  4. None of these


Correct Option: C

Cells which actually release the antibodies are 

  1. Helper T-cells

  2. Cytotoxic T-cells

  3. Suppressor T-cells

  4. Plasma cells


Correct Option: D
Explanation:

Antibodies are secreted by cells of the adaptive immune system; B cells, which are formed by the differentiation of the plasma cells. B lymphocytes have antibodies attached to them. Once they detect an antigen, they transform into plasma cells and secrete antibodies until the immune response is over. 

Monoclonal antibodies are

  1. Single parent type that attack many antigens

  2. Single parent type and attack specific antigen

  3. Various parent type and attack many antigens

  4. Various parent type and attack single antigen


Correct Option: B
Explanation:

If the identical antibodies are produced by the single clone of cells such antibodies are called as monoclonal antibodies. They are clones or single type but they are target specific. Each monoclonal antibody recognizes one particular protein (antigen). They work in different ways depending on the protein they are targeting. Thus, the correct answer is option B.

Antibodies combine with antigens

  1. at variable regions

  2. at constant regions

  3. only if macrophages are present

  4. both (a) and (C)


Correct Option: A
Explanation:

In the blood, the antigens are specifically and with high affinity bound by antibodies to form an antigen-antibody complex. The antigenic determinant or epitope is recognized by the paratope of an antibody, situated at the variable region of the polypeptide chain.

So, the correct option is 'At variable regions'.

Which one of the following statements is correct with respect to immunity?

  1. Preformed antibodies need to be injected to treat the bite by a viper snake

  2. The antibodies against small pox pathogen are produced by T-lymphocytes

  3. Antibodies are protein molecules, each of which has four light chains

  4. Rejection of a kidney graft is the function of B-lymphocytes


Correct Option: A
Explanation:

A. Anti-snake venom is made by collecting venom from the snake and injecting small amounts of it usually into a horse. The antibodies that form in the horse blood are then collected and used to treat a snake bite case by injecting directly to the affected person.
B. Antibodies against smallpox are produced by B-lymphocytes.
C. Antibodies contain 2 light chains and 2 heavy chains.
D. Rejection of a kidney graft is a function of T-lymphocytes.

So, the correct answer is, 'Preformed antibodies need to be injected to treat the bite by a viper snake'.

What are antibodies chemically composed of?

  1. Lipid

  2. Nucleoprotein

  3. Carbohydrate

  4. Protein


Correct Option: D
Explanation:

Antibodies are nothing but proteins. There are 5 types of antibodies, IgG, IgM, IgA, IgE, IgD. They are produced by B lymphocytes. 

So, option D is the correct answer.

Condition in which immune system fails is

  1. Allergy

  2. AIDS

  3. Tetanus

  4. Typhoid


Correct Option: B

Antibodies are produced in

  1. Human body

  2. Industries

  3. Pharmacy

  4. None of the above


Correct Option: A

Antibodies are also known as

  1. Immunoglobulin

  2. Anti-toxin

  3. Immunogen

  4. None of the above


Correct Option: A
Explanation:

Immunoglobulins are the proteinaceous substances produced by the immune cells (B cell) that function as antibodies. The terms antibody and immunoglobulin are often used interchangeably. Thus, the correct answer is option A.

Antibodies recognize

  1. Antigens

  2. Germs

  3. Diseases

  4. None of the above


Correct Option: A
Explanation:

Antibodies are small proteinaceous substance made by the immune cells. Antibodies attach to proteins and other chemicals in the body, which they recognise to be not normally found in the body ('foreign'). The foreign proteins and chemicals that antibodies attach to are called as antigens. Thus, the correct answer is option A.

Antibodies are formed by

  1. Plasma cells

  2. Histiocytes

  3. Mast cells

  4. None of the above


Correct Option: A
Explanation:
  • Antibodies are produced by specialized white blood cells called B lymphocytes (or B cells).
  • B lymphocytes are activated on their encounter with foreign agents. These foreign particles act as foreign markers.
  • The B-cells immediately differentiate into plasma cells and memory cells. The plasma cells produce antibodies specific to that foreign particle or so-called antigen.
  • These antibodies attach to the surface of the antigen/foreign agent.
  • These antibodies detect any antigen in the body and destroy it.
  • Hence Antibodies are formed by Plasma cells.
  • So, the correct answer is 'Plasma cells'.

Antibody which mediates allergic response is 

  1. IgA

  2. IgD

  3. IgE

  4. IgM


Correct Option: C
Explanation:

Immunoglobulin E (IgE) is a type of antibody that has been found only in mammals. IgE is synthesised by plasma cells. IgE also has an essential role in type I hypersensitivity which includes allergic diseases, such as allergic asthma, sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis.

So, the correct answer is 'IgE'.

Antibody production is carried out by 

  1. Monocytes

  2. leuococytes

  3. Lymphocytes

  4. Erythrocytes


Correct Option: C
Explanation:

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic adaptive immunity), and B cells (for humoral, antibody-driven adaptive immunity). They are the main type of cell found in lymph. Lymphocytes are involved in the activation of the immune system. Hence, B-lymphocytes are involved in the production of an antibody.

So, the correct answer is 'Lymphocytes'.

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