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Vaccines - class-XII

Description: vaccines
Number of Questions: 21
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Tags: immunity biology animal physiology
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Who discovered the smallpox vaccine?

  1. Louis Pasteur

  2. Edward Jenner

  3. Alexander Fleming

  4. Anton van Leeuwenhoek


Correct Option: B
Explanation:

Smallpox vaccine was introduced by Edward Jenner in 1798. He observed that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. Smallpox vaccine was the first successful vaccine.

Therefore, the correct answer is option B.

Which of the following diseases can be prevented by vaccines ?

  1. Cancer

  2. Swine Flu

  3. Both B and D

  4. Polio


Correct Option: C
Explanation:

Swine flu and polio can be prevented by giving vaccination at the right time. There are many more diseases which can be prevented by vaccines. Therefore, (c) is the correct answer.

Column I Column II
A Edward Jenner I Heredity
B Chromosomes II Budding
C Hydra III Protein biosynthesis
IV Smallpox
V Cell membrane
VI Binary fission
VII Antiboitics

Select the correct alternatives.

  1. A- VIII, B- I, C- II

  2. A- IV, B- I, C- II

  3. A-VII, B-V, C-VI

  4. A- IV, B- II, C- VI


Correct Option: B
Explanation:

Edward Jenner was an English physician and scientist who was the pioneer of smallpox vaccine, the world's first vaccine. He is often called the father of immunology. Heredity refers to the transfer of biological characteristics from a parent organism to offspring. DNA in the form of large molecules known as chromosomes which is the carrier of genetic instructions for the development and functioning of living organisms. Hydras generally reproduce asexually. They do this through budding.

Vaccine developed by Pasteur was against

  1. Chicken pox

  2. Anthrax

  3. Rabies

  4. Both B and C


Correct Option: D
Explanation:
During the mid- to late 19th century Pasteur demonstrated that microorganisms cause disease and discovered how to make vaccines from weakened, or attenuated, microbes. He developed the earliest vaccines against fowl cholera, anthrax, and rabies.

So, the correct answer is 'Both B and C'.

Which of the following diseases has been eradicated by vaccination?

  1. Typhoid

  2. Chickenpox

  3. Smallpox

  4. Kala-azar


Correct Option: C
Explanation:

The smallpox vaccine is made from the weekend virus called Vaccinia, which is another smallpox-type virus that cannot cause infections. This vaccine helps the body develop immunity to smallpox and thus successfully eradicate smallpox from the human population.

Who discovered vaccination against small pox?

  1. Jenner

  2. Pasteur

  3. Lister

  4. Mayer


Correct Option: A
Explanation:
Edward Jenner found that vaccination with cowpox can protect individuals from smallpox. Edward Jenner was well known for his contribution to immunization and eradication of smallpox. Jenner's work was widely regarded as the foundation of immunology and known as the father of immunology. The smallpox vaccine was the only way to prevent smallpox. The vaccine was made from a virus either weakened or attenuated, which was introduced into the blood. This helps in building antibodies against the smallpox virus in the body. Smallpox was eradicated by this vaccination program, starting in 1967. 
Thus, the correct answer is option 'Jenner'.

Vaccination against small pox means the introduction of  

  1. Leucocytes obtained from an animal

  2. Antibodies produced in other animals

  3. Antibodies

  4. Actual weakened germs or attenuated small pox virus


Correct Option: D
Explanation:

The smallpox vaccine is the only way to prevent smallpox. The vaccine is made from a virus either weakened or attenuated (has lost its ability to cause the disease), which is introduced into the blood. This helps in building the antibodies against the smallpox virus in the body. Smallpox was eradicated by this vaccination program, starting in 1967. 

The methods of administering vaccines _________

  1. Inoculation

  2. Orally

  3. Both A and B

  4. None of these


Correct Option: C
Explanation:

The methods of administering vaccines is by inoculation, but some are given orally. A vaccine produces immunity to a disease by stimulating the production of antibodies.

Vaccine is example of ___________ immunity.

  1. Natural acquired active immunity

  2. Natural acquired passive immunity

  3. Artificial acquired active immunity

  4. Artificial acquired passive immunity


Correct Option: C
Explanation:

Vaccines contain dead or alive but attenuated pathogens or toxoids consisting of microbial components. Vaccines is introduces into the body to stimulate the formation of antibodies by the immune system.

Jenner prepared vaccine for small pox virus by employing

  1. Attenuated small pox virus

  2. Small doses of small pox virus

  3. Attenuated cow's pox virus

  4. Large doses of small pox virus


Correct Option: C
Explanation:

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Edward Jenner administered the world’s first vaccination as a preventive treatment for smallpox. He took fluid from a cowpox blister, attenuated the cowpox virus and introduced it into the skin of James Phipps, an eight-year-old boy who is suffering from smallpox. A single blister rose up on the spot, but James soon recovered.

So, the correct answer is 'Attenuated cow's pox virus'.

The technique of preparing vaccine from attenuated pathogen was discovered by 

  1. Edward Jenner (1796)

  2. Robert Koch (1876)

  3. Louis Pasteur (1879)

  4. Von Behring (1891)


Correct Option: C
Explanation:

An attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (live). Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent. The technique of preparing vaccine from attenuated pathogen was first discovered by Louis Pasteur in 1879 against anthrax and rabies.

So, the correct answer is 'Louis Pasteur (1879)'.

Which of the following established the scientific basis of vaccination?

  1. Louis Pasteur

  2. John Mendel

  3. Cesar Milstein

  4. George Kohler


Correct Option: A
Explanation:
  • Louis Pasteur (1822-1895) demonstrated that microorganisms cause both fermentation and disease, which support the germ theory of disease. He developed the earliest vaccines against anthrax.

The process of vaccination was discovered by

  1. Edward Jenner (1796)

  2. Robert Koch (1876)

  3. Louis Pasteur (1879)

  4. Von Behring (1891)


Correct Option: A
Explanation:

  • Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen.
  •  It is the most effective method of preventing infectious diseases, widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio, measles, and tetanus from much of the world.
  •  Edward Jenner discovered the process of vaccination in 1796 by introducing material from cowpox vesicle.
So, the correct answer is 'Edward Jenner (1796)'.

The term vaccine was introduced by

  1. Jenner

  2. Koch

  3. Pasteur

  4. Both B and C


Correct Option: A
Explanation:

  • A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future.
  • The terms vaccine and vaccination are derived from smallpox of a cow were introduced by Edward Jenner.
So, the correct answer is 'Jenner'.

'Salk' vaccine is used for vaccination against

  1. Smallpox

  2. Polio

  3. Rabies

  4. Measles


Correct Option: B
Explanation:

The polio vaccine was developed in 1955 by Dr. Jonas Salk and thus called the “Salk vaccine”. It is the inactivated or killed vaccine that was given by intramuscular injection but now it is given orally. The inactivated polio vaccine produces antibodies in the blood to all three types of poliovirus. In the event of infection, these antibodies prevent the spread of the virus to the central nervous system and protect against paralysis. 

The first vaccine produced by Edward Jennar was for protection against

  1. Hepatitis

  2. Influenza

  3. Chicken pox

  4. Small pox


Correct Option: D
Explanation:
  • Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. 
  • He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox. 
  • Hence, The first vaccine produced by Edward Jenner was for protection against Smallpox  
  • So, the correct answer is 'Smallpox'.

Prior to vaccination, people used to protect themselves from small pox through

  1. Worship

  2. Hygiene and nutrition

  3. Variolation

  4. Getting infected with cow pox


Correct Option: C

Vaccine which provides immunization against polio was developed by

  1. E. Jenner

  2. Dr. Salk

  3. J. Lederberg

  4. Landsteiner


Correct Option: B
Explanation:

The polio vaccine was developed in 1955 by Dr. Jonas Salk and thus called the “Salk vaccine”. It is the inactivated or killed vaccine that was given by intramuscular injection but now it is given orally.

Variolation was practised in

  1. Brazil

  2. East

  3. West

  4. Australia


Correct Option: B

Vaccine against rabies was first developed by 

  1. Jenner

  2. Shull

  3. Pasteur

  4. Gorger


Correct Option: C
Explanation:
  • Rabies is a viral disease caused by the rabies virus that causes inflammation of the brain in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure.
  • Virtually all infections with rabies resulted in death until two French scientists, Louis Pasteur and Émile Roux, developed the first rabies vaccination in 1885.
  • Hence vaccine against rabies was first developed by Pasteur.
  • So, the correct answer is 'Pasteur'.

Pulse Polio Immunization involves vaccination of all children between the ages of _______

  1. 5 to 10 years

  2. 0 to 5 years

  3. 1 to 9 years

  4. 10 to 15 years


Correct Option: B
Explanation:

Explanation: Pulse Polio Immunization is a program initiated by the Government of India, where children between the ages of 0 to 5 years are administered oral polio vaccine twice a year to interrupt transmission of polio.

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