• Chromosomal Basis of Inheritence
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Chromosomal Basis of Inheritence

Description: test contains 31 mcq and is an important topic for medical enterance exam
Number of Questions: 31
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Tags: chromosome AIPMT Chromosomal Theory of Inheritance Sex Determination in Human Beings Sex Determination Genetics Principles of Inheritance and Variation Linkage and Crossing Over Linkage and Recombination of Genes Mutation
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Who among the following observed sperm and egg?

  1. Strasburger

  2. Hartwig

  3. Bendon

  4. Waldeyer

  5. None of these

Show answer
Correct Option: B
Explanation:

He observed sperm and egg.

Who discovered episome?

  1. Hays and Lederberg

  2. Hays and Wollmann

  3. Jacob and Lederberg

  4. Jacob and Wollmann

  5. None of these

Show answer
Correct Option: D
Explanation:

Jacob and Wollmann discovered episome.

Who gave chromosomal theory of inheritence?

  1. Sutton and Bovery

  2. Bateson and Punnet

  3. Dr Lalji Singh and Dr V.K. Kashyap

  4. Morgan

  5. None of these

Show answer
Correct Option: A
Explanation:

They gave chromosomal theory of inheritence.

Which of the following statements is correct regarding histone proteins?

  1. They are acidic proteins and are present in prokaryotes.

  2. They are basic proteins and are present in prokaryotes.

  3. They are acidic proteins and are present in eukaryotes.

  4. They are basic proteins and are present in eukaryotes.

  5. None of these

Show answer
Correct Option: D
Explanation:

Histones are basic proteins and are present in eukaryotes.

Which non-histone protein forms central axis of chromosomes?

  1. Structural non-histone protein.

  2. Regulatory non-histone protein.

  3. Enzymatic non-histone protein.

  4. H1

  5. None of these.

Show answer
Correct Option: A
Explanation:

It forms central axis of chromosome and is also known as scaffold protein.

XX-XY type of sex determination is present in __________.

  1. dioscorea

  2. sphaerocarpous

  3. fragaria

  4. moth

  5. all of these

Show answer
Correct Option: B
Explanation:

It has XX-XY type of sex determination.

Which of the following plants has the maximum number of chromosomes?

  1. Aulocantha

  2. Ophioglossum reticulatum

  3. Mucor

  4. Haplopappus gracilus

  5. None of these

Show answer
Correct Option: B
Explanation:

It is a plant which has maximum number of chromosomes.

Environmental type of sex determination is seen in ______________.

  1. crepidula

  2. hydrilla

  3. cockroach

  4. birds

  5. butterfly

Show answer
Correct Option: A
Explanation:

It shows environmental type of sex determination. If embryo grows along with female, then the offspring will be male and if embryo is kept in isolation, then the offspring will be female.

What would be sex of drosophila with 2A + XXX genetic constitution?

  1. Normal male

  2. Normal female

  3. Meta male

  4. Intersex

  5. Meta female

Show answer
Correct Option: E
Explanation:

For it, X / A ratio should be greater than 1. So, when we calculate X/A = 3 / 2 = 1.5.

Which of the following gave chromosomal theory of sex determination?

  1. Sutton and Bovery

  2. Wilson and Steven

  3. Finch and Klug

  4. Kornberg and Thomas

  5. None of these

Show answer
Correct Option: B
Explanation:

They gave chromosomal theory of sex determination.

What would be the linkage group in case of human male?

  1. 23

  2. 24

  3. 46

  4. 22

  5. None of these

Show answer
Correct Option: B
Explanation:

Linkage group is equal to haploid set of chromosome, but since in male there is Y chromosome, so total linkage group will be 23 + 1 = 24.

ZZ-ZO type of sex determination is opposite to ______________.

  1. ZZ-ZW type

  2. XX-XY type

  3. XX-XO type

  4. All of these

  5. None of these

Show answer
Correct Option: C
Explanation:

Here O determines sex of femaleness whereas in XX-XO type O determines sex of maleness.

What will be linkage group in wheat?

  1. 21

  2. 7

  3. 10

  4. 4

  5. 1

Show answer
Correct Option: B
Explanation:

2n = 6x = 42 Therefore 42 / 6 = 7. Thus 7 linkage group.

Deficiency of which of the following leads to alkaptonuria?

  1. Tyrosinase enzyme

  2. Oxidase enzyme

  3. Hexosaminidase B

  4. Glucocerebrosidase enzyme

  5. Phenylalanine hydroxylase

Show answer
Correct Option: B
Explanation:

Its deficiency leads to alkaptonuria.

Which of the following types of DNA has 11 base pairs per turn?

  1. B DNA

  2. A DNA

  3. C DNA

  4. Z DNA

  5. None of these

Show answer
Correct Option: B
Explanation:

It has 11 base pairs per turn.

Which of the following is due to trisomy of 18 chromosomes?

  1. Autosomal abnormality that is Edward's syndrome

  2. Allosomal abnormality that is Edward's syndrome

  3. Autosomal abnormality that is Patau's syndrome

  4. Allosomal abnormality that is Patau's syndrome

  5. Autosomal abnormality that is down's syndrome

Show answer
Correct Option: A
Explanation:

It is due to trisomy of 18 chromosomes.

Who gave one gene-one polypeptide hypothesis?

  1. Beadle and Tatum

  2. Yanofsky

  3. Jacobson and Baltimore

  4. De Vries

  5. None of these

Show answer
Correct Option: B
Explanation:

He gave one gene-one polypeptide hypothesis.

Which of the following is a small sized uridine rich RNA that takes part in splicing and processing of other RNAs?

  1. Genetic RNA

  2. ScRNA

  3. SnRNA

  4. tRNA

  5. None of these

Show answer
Correct Option: C
Explanation:

It is small sized uridine rich RNAs that take part in splicing and processing of other RNAs.

Which enzymes help in unwinding DNA helix in prokaryotes during replication?

  1. Gyrase

  2. Helicase

  3. Topoisomerase

  4. DNA polymerase

  5. DNA Ligase

Show answer
Correct Option: A
Explanation:

It is the enzyme which helps in unwinding DNA helix in prokaryotes.

Genetic code is non-ambiguous except in case of _____________.

  1. UUA

  2. AUG

  3. UCU

  4. CCU

  5. GUG

Show answer
Correct Option: E
Explanation:

It codes for both methionine and valine, and thus ambiguous in nature.

Which antibiotic inhibits peptidyl transferase and peptide bond formation?

  1. Tetracycline

  2. Streptomycin

  3. Neomycin

  4. Chloramphenicol

  5. Erythromycin

Show answer
Correct Option: D
Explanation:

It inhibits peptidyl transferase and peptide bond formation.

Who is the father of genetic engineering?

  1. Cohen and Boyer

  2. Paul Berg

  3. Gamow

  4. Bateson

  5. Morgan

Show answer
Correct Option: B
Explanation:

He is father of genetic engineering.

Which of the following restriction enzyme gives blunt end cut?

  1. Eco RI

  2. Bam HI

  3. Hind III

  4. Pvu I

  5. Sma I

Show answer
Correct Option: E
Explanation:

It gives blunt end cut.

What is name of first clone of an African toad?

  1. Dolly

  2. Gurdon

  3. ANDi

  4. Noah

  5. None of these

Show answer
Correct Option: B
Explanation:

It is the first clone of an African toad.

Human genome consists of _______genes.

  1. 4000

  2. 6000

  3. 18000

  4. 13000

  5. 30000

Show answer
Correct Option: E
Explanation:

It is in case of humans.

Which of the following has 4.7 million base pairs?

  1. E.coli

  2. Sacchromyces cereviceae

  3. Coaenorhabditis elegans

  4. Drosophila melanogaster

  5. None of these

Show answer
Correct Option: A
Explanation:

It has 4.7 million base pairs.

What is number of genes in drosophila melanogaster?

  1. 4000

  2. 6000

  3. 18000

  4. 13000

  5. 30000

Show answer
Correct Option: D
Explanation:

It is in case of drosophila melanogaster.

Who is father of DNA finger printing?

  1. Sir Alec Jeffreys

  2. Dr. Lalji Singh and Dr. V.K Kashyap

  3. Karry Mulis

  4. Paul Berg

  5. None of these.

Show answer
Correct Option: A
Explanation:

He was the father of DNA finger printing.

__________ is known as green colour blindness.

  1. Protanopia

  2. Tritanopia

  3. Deuteranopia

  4. Daltonism

  5. None of these

Show answer
Correct Option: C
Explanation:

It is green colour blindness.

What is the possibility of a couple to have one son and one daughter?

  1. 50%

  2. 25%

  3. 75%

  4. 100%

  5. None of these

Show answer
Correct Option: A
Explanation:

According to Pascal triangle, the ratio to be used for two children will be 1 : 2 : 1. Here, 1 represents two sons, 2 represents one son and one daughter, 1 represents two daughters, respectively. So, probability of one son and one daughter is 2/4, i.e. 1/2 x 100 = 50%.

How many chromonemata are present in metaphase and anaphase of cell cycle?

  1. 2 and 1 respectively

  2. 1 and 2 respectively

  3. 1 and 1 respectively

  4. 2 and 2 respectively

  5. None of these

Show answer
Correct Option: A
Explanation:

Number of chromonemata is equal to number of chromatids. Number of chromatids in metaphase is 2 and in anaphase is 1.

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