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Chemical Coordination and Integration - II (Class XI)

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Which of the following hormones targets the melanocyte cells present in the skin?

  1. MSH

  2. Aldosterone

  3. ICSH

  4. Somatostatin

  5. ACTH


Correct Option: A
Explanation:

MSH or Melanocyte stimulating hormone is the hormone made up of long chain peptides and targets the melanocyte cells present in the skin.

Which of the following diseases is caused due to the excess secretion of thyroxine?

  1. Diabetes insipidus

  2. Gull's disease

  3. Osteitis fibrosa cystica

  4. IDDM

  5. Graves disease


Correct Option: E
Explanation:

It is caused due to the excess secretion of thyroxine or hyperthyroidism.

Which of the following is an autoimmune disease caused by sensitisation of thyroglobulin?

  1. Polyuria

  2. Precocious puberty

  3. Hashimoto goitre

  4. Graves disease

  5. Osteitis fibrosa cystica


Correct Option: C
Explanation:

It is an autoimmune disease caused due to sensitisation of thyroglobulin.

Which of the following hormones is secreted by the intermediate lobe of pituitary?

  1. Somatotropin

  2. MSH

  3. ADH

  4. TSH

  5. Oxytocin


Correct Option: B
Explanation:

MSH or Melanocyte stimulating hormone is the hormone made up of long chain peptides and is secreted by the intermediate lobe of pituitary.

Collip's hormone is secreted by which of the following?

  1. Pituitary gland

  2. Parathyroid

  3. Pineal gland

  4. Adrenal

  5. Hypothalamus


Correct Option: B
Explanation:

The major hormonal secretion of the parathyroid gland is known as parathormone or Collip's hormone.

Which of the following endocrine glands is responsible for the proliferation and maturation of T-cells?

  1. Thymus

  2. Pineal

  3. Adrenal

  4. Pituitary

  5. Hypothalamus


Correct Option: A
Explanation:

Thymus is known as the training school of T-lymphocytes and is responsible for the proliferation and maturation of T-lymphocytes.

Which of the following hormones is stimulated by the sympathetic nervous system for meeting an emergency situation?

  1. Somatotropin

  2. Progesterone

  3. Thyroxine

  4. Epinephrine

  5. Insulin


Correct Option: D
Explanation:

It is stimulated by the sympathetic nervous system for meeting an emergency.

Oversecretion of aldosterone due to adrenal cortical tumour in the region of zona glomerulosa results in which of the following?

  1. Conn's syndrome

  2. Adrenal virilism

  3. Addison's disease

  4. Cushing syndrome

  5. Acromicra


Correct Option: A
Explanation:

Oversecretion of aldosterone due to adrenal cortical tumour in the region of zona glomerulosa results in Conn's syndrome.

Which of the following hormones is secreted by the delta cells of the islets of Langerhans?

  1. Glucagon

  2. Gastrin

  3. Insulin

  4. Somatostatin

  5. Pancreatic polypeptide


Correct Option: D
Explanation:

It is released by the delta cells of the islets of Langerhans and keeps a check on the excessive secretion of the alpha and beta cells.

Which of the following causes parathyroid tetany?

  1. Hypoparathyroidism

  2. Hypogonadism

  3. Hyperparathyroidism

  4. Hypothyroidism

  5. Hyperglycaemia


Correct Option: A
Explanation:

It is the phenomenon of hyposecretion of PTH by parathyroid due to autoimmune disease, genetic disease or accidental damage to the glands. It leads to hypercalcemic or parathyroid tetany.

Which of the following endocrine glands is a double gland with functionally unrelated parts?

  1. Parathyroid gland

  2. Pineal gland

  3. Adrenal gland

  4. Placenta

  5. Pituitary


Correct Option: C
Explanation:

It is a double gland fitted over the upper ends of kidneys and has two parts, namely adrenal cortex (mesodermal origin) and adrenal medulla (ectodermal origin). These parts are functionally unrelated.

Which of the following stimulates progesterone release from the corpus luteum and maintains it?

  1. Testosterone

  2. hCG

  3. Relaxin

  4. Human placental lactogen

  5. Estrogen


Correct Option: B
Explanation:

hCG (Human chorionic gonadotropin) stimulates progesterone release from the corpus luteum and maintains it.

Which of the following hormones is released by heart muscles and helps to reduce blood pressure?

  1. Villikinin

  2. Pancreozymin

  3. Atrial natriuretic factor

  4. Gastrin

  5. Renin


Correct Option: C
Explanation:

Atrial natriuretic factor is the hormone secreted by heart. It helps in maintaining blood volume and reducing blood pressure.

Which of the following hormones of the gastrointestinal tract stimulates secretion of mucus from Brunner's gland?

  1. Enterogastrone

  2. Pancreozymin

  3. Duocrinin

  4. Secretin

  5. Villikinin


Correct Option: C
Explanation:

It is an intestinal hormone that stimulates secretion of mucus from Brunner's gland.

Which of the following endocrine glands is of mesodermal origin?

  1. Liver

  2. Hypothalamus

  3. Pituitary

  4. Pancreas

  5. Placenta


Correct Option: E
Explanation:

It is an endocrine gland of mesodermal origin and helps in maintenance of corpus luteum and the continued secretion of progesterone.

Kidney is the target organ of which of the following hormones of adrenal glands?

  1. Norepinephrine

  2. Cortisone

  3. Aldosterone

  4. Cortisol

  5. Estrogen


Correct Option: C
Explanation:

It is secreted by the adrenal gland and its target tissue is kidney.

Which of the following diseases is characterised by puffy appearance caused by waxy swelling of skin due to abnormal deposition of glycosaminoglycans in the skin and other tissues?

  1. Cretenism

  2. Gull's disease

  3. Acromegaly

  4. Hypogonadism

  5. Endemic goitre


Correct Option: B
Explanation:

It is caused due to deficiency of thyroxine and is characterised by puffy appearance caused by waxy swelling of skin due to abnormal deposition of glycosaminoglycans in the skin and other tissues.

Which of the following is the main mineralocorticoid of human body?

  1. Pancreozymin

  2. Villikinin

  3. Cortisol

  4. Insulin

  5. Aldosterone


Correct Option: E
Explanation:

It is a mineralocorticoid secreted by the zona glomerulosa of adrenal cortex. It is the main mineralocorticoid of human body.

Cholecystokinin is produced by which of the following?

  1. Duodenum

  2. Heart

  3. Liver

  4. Intestinal mucosa

  5. Pyloric mucosa


Correct Option: A
Explanation:

Cholecystokinin is produced by duodenum in response to the presence of food. It causes contraction of gall bladder for releasing bile.

Brain sand is present in

  1. placenta

  2. ovaries

  3. pineal gland

  4. pituitary gland

  5. thyroid gland


Correct Option: C
Explanation:

Corpora arenacea (or brain sand) are calcified structures in the pineal gland.

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