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Biomolecules (GATE - XL)

Description: GATE
Number of Questions: 15
Created by:
Tags: GATE Proteins Metabolism and Bioenergetics Enzyme Catalysis Classification and Structure of Proteins in Food Amino Acids and Nucleotides A general Account of Economically and Medicinally Important Plants- Cereals
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Which of the following is a pair of ketohexoses?

  1. Mannose and talose

  2. Sorbose and psicose

  3. Arabinose and xylose

  4. Ribulose and xylulose

  5. Erythrose and erythrulose

Show answer
Correct Option: B
Explanation:

Correct answer. Sorbose and psicose are examples of ketohexoses.

In which of the following is the coordination number of iron 6?

  1. Cytochrome complex
  2. Rubredoxin
  3. Ferredoxin

  1. Only 1

  2. Only 2

  3. Only 3

  4. Both 1 and 2

  5. Both 2 and 3

Show answer
Correct Option: A
Explanation:

Coordination number of iron in cytochrome complex is 6. So, this is the correct answer.

Identify the incorrect statement(s) about peptide linkage.

  1. C-N bond length in peptide link is intermediate in length between typical carbon-nitrogen single bond and carbon-nitrogen double bond.
  2. Peptide bond is planar.
  3. The two alpha carbon atoms attached to C-N are always cis to each other.

  1. Only 1

  2. Only 2

  3. Only 3

  4. Both 1 and 2

  5. Both 2 and 3

Show answer
Correct Option: C
Explanation:

Correct answer. The two alpha carbon atoms attached to C-N are always trans to each other (on the opposite side of the peptide linkage).

Which of the following is an example of copper-containing metalloprotein?

  1. Ferritin

  2. Alcohol dehydrogenase

  3. Calmodulin

  4. Dinitrogenase

  5. Plasocyanin

Show answer
Correct Option: E
Explanation:

Plasocyanin is an example of copper-containing metalloprotein.

Match the entries in column I (protein) and column II (isoelectric point) and select the correct answer.

 
Column I
Column II
P. Urease 1. 5.0
Q. Haemoglobin 2. 6.8
R. Chymotrypsinogen 3. 9.5
S. Lysozyme 4. 11.0

  1. P - 1; Q - 2; R - 3; S - 4

  2. P - 2; Q - 1; R - 3; S - 4

  3. P - 3; Q - 2; R - 4; S - 1

  4. P - 3; Q - 2; R - 1; S - 4

  5. P - 4; Q - 3; R - 2; S - 1

Show answer
Correct Option: A
Explanation:

Correct answer. Isoelectric point of urease is 5.0. Isoelectric point of haemoglobin is 6.8. Isoelectric point of chymotrypsinogen is 9.5. Isoelectric point of lysozyme is11.0.

Which among the following proteins is made up of five polypeptide chains?

  1. Myoglobin

  2. Haemoglobin

  3. Chymotrypsinogen

  4. RNA polymerase

  5. Titin

Show answer
Correct Option: D
Explanation:

Correct answer. RNA polymerase is made up of five polypeptide chains.

Which among the following proteins has the largest number of polypeptide chains?

  1. Ribonuclease A

  2. Lysozyme

  3. Chymotrypsin

  4. Hexokinase

  5. Glutamine synthase

Show answer
Correct Option: E
Explanation:

Correct answer. Glutamine synthase is made up of twelve polypeptide chains.

Which of the following is a pair of zinc-containing enzymes?

  1. Carboxypeptidase and ATPase

  2. Carbonic anhydrase and phosphoglucomutase

  3. Carbonic anhydrase and carboxypeptidase

  4. ATPase and phosphoglucomutase

  5. Phosphoglucomutase and carboxypeptidase

Show answer
Correct Option: C
Explanation:

This option is correct because carboxypeptidase and carbonic anhydrase are zinc-containing enzymes.

Match the following:

 
Column I (Enzyme)
Column II (Metal ion)
P. Cytochrome oxidase 1. Ni2+
Q. Hexokinase 2. Cu2+
R. Arginase 3. Mg2+
S. Urease 4. Mn2+

  1. P - 1; Q - 3; R - 2; S - 4

  2. P - 2; Q - 3; R - 4; S - 1

  3. P - 3; Q - 1; R - 4; S - 2

  4. P - 4; Q - 2; R - 3; S - 1

  5. P - 4; Q - 1; R - 2; S - 3

Show answer
Correct Option: B
Explanation:

Correct answer. The correct matching is: Cytochrome oxidase: Cu2+ Hexokinase: Mg2+ Arginase: Mn2+ Urease: Ni2+

Match the following Fe containing proteins with the corresponding function and oxidation state of Fe.

   
Fe containing proteins
Function
Oxidation state of Fe
P. Haemoglobin i. Plasma O2 transport a. 2
Q. Myoglobin ii. Muscle O2 storage b. 3
R. Transferrin iii. Plasma Fe transport
S. Catalase iv. H2O2 metabolism

  1. P - ii - a, Q - iv - b, R - i - b, S - iii - b

  2. P - iii - a, Q - iv - a, R - ii - b, S - i - b

  3. P - i - a, Q - ii - a, R - iii - b, S - iv - a

  4. P - ii - b, Q - iii - b, R - iv - a, S - i - a

  5. P - i - b, Q - iii - b, R - ii - a, S - iv - b

Show answer
Correct Option: C
Explanation:

This is the correct answer. Haemoglobin is a plasma O2 transport protein. Oxidation number of Fe in haemoglobin is 2. Myoglobin is a muscle O2 storage protein. Oxidation number of Fe in myoglobin is 2. Transferrin is a plasma Fe transport protein. Oxidation number of Fe in transferrin is 3. Catalase is an enzyme, which catalyses H2O2 metabolism. Oxidation number of Fe in catalase is 2.

Which of the following enzymes contains both zinc as well as magnesium ions?

  1. Inorganic pyrophosphatase

  2. Alkaline phosphatase

  3. Collagenase

  4. ATPase

  5. Alcohol dehydrogenase

Show answer
Correct Option: B
Explanation:

Alkaline phosphatase contains both zinc (Zn2+) and magnesium (Mg2+) ions.

Match the entries in column I (amino acid) and column II (single letter code) and select the correct answer.

 
Column I
Column II
P. Aspartate 1. N
Q. Glutamate 2. Q
R. Asparagine 3. D
S. Glutamine 4. E

  1. P - 1; Q - 2; R - 3; S - 4

  2. P - 2; Q - 1; R - 4; S - 3

  3. P - 3; Q - 2; R - 4; S - 1

  4. P - 3; Q - 4; R - 1; S - 2

  5. P - 4; Q - 3; R - 2; S - 1

Show answer
Correct Option: D
Explanation:

Correct answer. Single letter code for aspartate is D. Single letter code for glutamate is E. Single letter code for asparagine is N. Single letter code for glutamine is Q.

Match the entries in column I and column II and select the correct answer.

 
Column I
Column II
P. Immunoglobulin G 1. Hemoprotein
Q. Casein 2. Flavoprotein
R. Succinate dehydrogenase 3. Phosphoprotein
S. Haemoglobin 4. Glycoprotein

  1. P - 1; Q - 2; R - 3; S - 4

  2. P - 3; Q - 1; R - 4; S - 2

  3. P - 4; Q - 2; R - 3; S - 1

  4. P - 4; Q - 2; R - 1; S - 3

  5. P - 4; Q - 3; R - 2; S - 1

Show answer
Correct Option: E
Explanation:

Correct answer.

Immunoglobulin G is an example of glycoprotein. Casein is an example of phosphoprotein. Succinate dehydrogenase is an example of flavoprotein. Haemoglobin is an example of hemoprotein.

Match the entries in column I (coenzyme) and column II (its dietary precursor in mammals) and select the correct answer.

 
Column I
Column II
P. Coenzyme A 1. Vitamin B1
Q. Flavin adenine dinucleotide 2. Vitamin B6
R. Thiamine pyrophosphate 3. Vitamin B12
S. Pyridoxal phosphate 4. Vitamin B5

  1. P - 1; Q - 3; R - 2; S - 4

  2. P - 2; Q - 4; R - 1; S - 3

  3. P - 3; Q - 4; R - 1; S - 2

  4. P - 4; Q - 3; R - 1; S - 2

  5. P - 4; Q - 3; R - 2; S - 1

Show answer
Correct Option: D
Explanation:

Dietary precursor of coenzyme A is vitamin B5. Dietary precursor of flavin adenine dinucleotide is vitamin B12. Dietary precursor of thiamine pyrophosphate is vitamin B1. Dietary precursor of pyridoxal phosphate is vitamin B6.

Match the following drugs with their plant sources and medical uses.

   
Drug
Source plant
Medical use
P. Colchicine i. Opium 1. Cough
Q. Taxol ii. Autumn crocus 2. Gout
R. Digoxin iii. Pacific yew 3. Heart disease
S. Codeine iv. Foxglove 4. Cancer treatment

  1. P - ii - 3; Q - iv - 1; R - i - 2; S - iii - 4

  2. P - iii - 1; Q - iv - 2; R - ii - 4; S - i - 3

  3. P - i - 2; Q - ii - 4; R - iii - 2; S - iv - 3

  4. P - ii - 2; Q - iii - 4; R - iv - 3; S - i - 1

  5. P - i - 4; Q - iii - 1; R - ii - 3; S - iv - 2

Show answer
Correct Option: D
Explanation:

Colchicine is a pale-yellow crystalline alkaloid extracted from seeds. It is used in the treatment of gout. Taxol, obtained mainly from the bark of the yew tree, is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body. Digoxin, a purified cardiac glycoside extracted from the foxglove plant, is used to treat certain heart problems such as arrhythmias and heart failure. Codeine is a white, crystalline, slightly bitter alkaloid, obtained from opium and used in medicine, chiefly as an analgesic or sedative to inhibit coughing.

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