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Mitosis (Medical Entrance)

Description: proteins
Number of Questions: 15
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Tags: mitosis kinetochores chromatids Mitosis Chemistry
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What are kinetochores?

  1. The place where mitotic spindle fibres attach to centrioles.

  2. The place where mitotic spindle attaches to chromosomes.

  3. The place where both chromatids are attached to each other.

  4. The fibres which originate from centrioles and form spindle.


Correct Option: B
Explanation:

The place where mitotic spindle attaches to chromosomes is called kinetochore.

Which of the following events does not occur in anaphase?

  1. Division of centromere.

  2. The daughter chromosomes begin moving towards opposite poles of the cell due to the action of the spindle.

  3. Chromosomes arrange themselves at equatorial plane.

  4. Complete set of chromosomes assembles at each pole of the cell.


Correct Option: C
Explanation:

Chromosomes arrange themselves at equatorial plane in metaphase.

During which phase do the contents of the nucleus and cytoplasm divide?

  1. G1 phase

  2. G2 phase

  3. M phase

  4. S phase


Correct Option: C
Explanation:

During M phase, the contents of nucleus and cytoplasm are divided.

The end of M-phase is marked by

  1. end of telophase

  2. end of cytokinesis

  3. end of cell cycle

  4. end of interphase


Correct Option: B
Explanation:

End of cytokinesis marks the end of M-phase. 

Disintegration of nuclear envelope takes place at

  1. prometaphase

  2. early anaphase

  3. prophase

  4. metaphase


Correct Option: A
Explanation:

Disintegration of nuclear envelope takes place at prometaphase.

The lost arm of a starfish can be regenerated by

  1. meiosis

  2. mitosis

  3. meiosis and mitosis

  4. binary fission


Correct Option: B
Explanation:

The lost arm of a starfish can be regenerated by mitotic divisions.

Which phase exists in nerve cells at maturity?

  1. G2

  2. G1

  3. G0

  4. S


Correct Option: C
Explanation:

Nerve cells are in G0 phase at maturity. 

Nuclear membrane remains intact during mitosis in

  1. fungi

  2. dinoflagellates

  3. Both (1) and (2)

  4. bacteria


Correct Option: C
Explanation:

Nuclear membrane remains intact during mitosis in both fungi and dinoflagellates, 

During which phase does mitotic spindle formation initiate?

  1. Preprophase

  2. Prophase

  3. Prometaphase

  4. Metaphase


Correct Option: B
Explanation:

Mitotic spindle formation initiates at prophase.

Which protein binds two identical sister chromatids at centromere?

  1. Securin

  2. Separase

  3. Cohesin

  4. Condensin


Correct Option: C
Explanation:

Cohesin binds two identical sister chromatids at centromere.

During which phase do sister chromatids become full-fledged chromosomes?

  1. Telophase

  2. Anaphase

  3. Prometaphase

  4. Metaphase


Correct Option: B
Explanation:

The sister chromatids become full-fledged chromosomes at anaphase. 

When does kinetochore formation take place?

  1. Metaphase

  2. Prometaphase

  3. Anaphase

  4. Prophase


Correct Option: B
Explanation:

Kinetochore formation takes place in prometaphase around the centromere.

In telophase, nuclear envelope is formed and the chromosomes uncoil. What does this appear to be?

  1. Reverse of prophase

  2. Initiation of cytokinesis

  3. Initiation of meiosis

  4. End of cell cycle


Correct Option: A
Explanation:

Formation of nuclear envelope and uncoiling of chromosomes signifies reverse of prophase.

Which of the following sentences is incorrect?

  1. The nucleolus disappears during early prophase.

  2. Centrosomes are essential for spindle formation.

  3. A single centromere is inherited by a cell during cell division.

  4. Centrosomes polymerise a protein called tubulin to help form the microtubule apparatus.


Correct Option: B
Explanation:

Centrosomes are not essential for spindle formation. 

What are the percent-wise durations of the four steps of M-phase in cell cycle?

Prophase (P) Metaphase (M) Anaphase (A) Telophase (T)

  1. P - 3% M - 4% A - 1% T - 2%

  2. P - 1% M - 4% A - 3% T - 2%

  3. P - 3% M - 2% A - 1% T - 4%

  4. P - 2% M - 4% A - 1% T - 3%


Correct Option: A
Explanation:

This is the correct percent-wise distribution of time taken in each step.

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