Metabolism and Bioenergetics (GATE)
| Description: This is Topic Test for GATE | |
| Number of Questions: 15 | |
| Created by: Neema Pandya | |
| Tags: pentose phosphate pathway Metabolic Pathwaysglyoxylate cycle glycolysis Citric acid cycle Metabolism and Bioenergetics Biochemistry Life Sciences Pentose Phosphate Pathway TCA Cycle Glycolysis Oxidative Phosphorylation |
One of the products of PP pathway is erythrose-4-phosphate. It is used for the synthesis of
Most of the steps of pentose phosphate pathway occur in plants in
Which of the following statements about pentose phosphate pathway are correct?
a. It is an anabolic pathway. b. NADPH produced in this pathway is required for the prevention of the oxidative stress. c. The first step of PP pathway is a rate limiting step and is irreversible. d. Epimerase converts ketose ribulose-5-phosphate to aldose ribose-5-phosphate.
NADPH generated in PP pathway is used for which of the following?
a. Amino acid synthesis b. Steroid synthesis c. Fatty acid synthesis d. Reduced glutathione synthesis
Which of the following enzymes is not involved in TCA?
Which of the following products is not formed in non-oxidative PP pathway?
Which of the following events occur in the oxidative phase of PP pathway?
a. Two molecules of NADP+ are reduced to NADPH. b. 6-phosphogluconolactonase catalyses dehydrogenation reaction. c. CO2 is generated in this phase. d. The rate-limiting reaction of pentose phosphate pathway is catalysed by glucose-6-phosphatase.
Which of the following is the significance of glyoxylate cycle in pathogenic fungi?
Glucose-6-phosphate dehydrogenase (G6PDH) is the first enzyme that is required for initiation of pentose phosphate pathway. Which of the following is/are the effects of mutation in glucose-6-phosphate dehydrogenase (G6PDH)?
a. Liver problems in neonates b. Chronic granulomatous disease c. Resistance to malarial parasite d. Erythrocyte survival affected
The variants with altered glucose-6-phosphate dehydrogenase activity have been classified into five classes by WHO. The variants with severe deficiency with intermittent haemolysis belong to
Which of the following substrates leads to the synthesis of L-malate by malate synthase in glyoxylate pathway?
Several drugs and toxins inhibit oxidative phosphorylation. Even if a single enzyme is inhibited, the whole process comes to a halt. One such inhibitor is oligomycin, which is used as an antibiotic. It blocks which of the following enzymes?
NAD specific isocitrate dehydrogenase oxidises isocitrate in citric acid cycle. Which of the following acts as an activator of this enzyme?
Phosphoenolpyruvate carboxykinase reaction (an anaplerotic reaction) produces which of the following in animals?
Phosphoenolpyruvate (PEP) is formed during glycolysis or gluconeogenesis metabolic pathway. It is used by bacteria for which of the following?