0

Biology Test

Description: This test will boost the knowledge of learning aspirants about human physiology.
Number of Questions: 15
Created by:
Tags: Circulatory system Structure of Reproductive System Male Reproductive System The Defence Mechanism Immunity Bacterial Diseases Virus Biology
Attempted 0/15 Correct 0 Score 0

The largest number of deaths from infectious diseases are caused by ____________.

  1. AIDS

  2. Acute respiratory infections

  3. Diarrheal diseases

  4. Tuberculosis

  5. Measles


Correct Option: B
Explanation:

Acute respiratory infections kill approximately 3.5 million people each year.

Which of the following statements is correct regarding cytotoxic T-cells?

  1. These cells are usually CD4.

  2. They recognise native viral antigen.

  3. They are more readily produced by a dead virus rather than a live virus.

  4. They kill viruses directly.

  5. They restrict viral replication.


Correct Option: E
Explanation:

The infection of a virally-infected cell prevents the virus from utilising that cell for replication.

Which of the following nerves innervates the human penis?

  1. Labialscrotal nerve

  2. Sciatic nerve

  3. Sacral nerves 2, 3 and 4

  4. Genitofemoral nerve

  5. Sacral spinal nerve


Correct Option: C
Explanation:

Innervation of the penis comes from the pudendal nerve, which is made up of the 2nd, 3rd and 4th sacral nerves. The penile nerve (also known as the dorsal nerve of the penis) is the deepest branch of the pudendal nerve.

Opsonization of bacteria occurs through coating bacteria just with __________.

  1. C3b

  2. C8

  3. Membrane attack complex

  4. F(ab')2 IgG

  5. IgM


Correct Option: A
Explanation:

There are receptors for C3b on the surface of phagocytic cell.

The pyrogenic streptococcal exotoxins SPE, A, B, and C ____________.

  1. are M proteins

  2. cause post-streptococcal autoimmune disease

  3. produce high titers of anti-streptolysin O

  4. have hyaluronidase activity

  5. are superantigens


Correct Option: E
Explanation:

The superantigens combine with the framework regions of certain TCR V beta families irrespective of their complementarity determining regions.

Extracellular bacteria try to avoid killing by _____________.

  1. activating neutrophils

  2. accelerating complement activation

  3. synthesising capsules

  4. by deviating complement deposition to the cell membrane

  5. limiting variation in their antigens


Correct Option: C
Explanation:

Capsules do not adhere readily to phagocytic cells and may cover carbohydrate molecules, which could be recognised by phagocyte receptors.

The toxins released by bacterias and other microorganisms are neutralised by ___________.

  1. complement

  2. antibody

  3. toxoids

  4. PGE2

  5. proteolytic enzymes


Correct Option: B
Explanation:

Antibody may block the binding to a target cell and would increase the rate of removal of a toxin from circulation by immune complex formation.

Individuals lacking C8 or C9 are more prone to infection with which of the following type of bacterias?

  1. Haemophilus influenzae

  2. Bacillus anthrax

  3. Vibrio cholerae

  4. Neisseria

  5. Listeria monocytogenes


Correct Option: D
Explanation:

The membrane attack complex containing C8 and C9 is important for destroying the Neisseria bacterium.

Specific immunity to M. tuberculosis in mice, can be transferred to naive histocompatible recipients by which of the following?

  1. B-cells

  2. T-cells

  3. Macrophages

  4. Neutrophils

  5. IgG


Correct Option: B
Explanation:

T-cells are important for immunity to M. tuberculosis through the provision of Th1 cytokines,  such as IFN-gamma to activate macrophages containing the bacilli and perhaps also the participation of cytotoxic T-cells. The latter may kill macrophages,  which cannot be rescued by cytokines thereby releasing the bacteria to be taken up by fresh young macrophages. They can be activated to become killers.

Viral antigen shift involves which of the following changes?

  1. Single point mutation.

  2. Random point mutations.

  3. Interchange of large segments of the viral genome with other viruses.

  4. Rearrangement of the viral structural architecture.

  5. Regression to an earlier variant.


Correct Option: C
Explanation:

The ability to interchange large segments of the genome with a viral reservoir in other animal species is the basis of antigenic shift leading to radical change in antigen, particularly crucial antigens giving protective immunity such as the viral hemagglutinin.

Lepromatous leprosy is characterised by ______________.

  1. poor T-cell responses

  2. good cell-mediated immunity

  3. good lepromin dermal response

  4. poor B-cell responses

  5. poor phagocytic ability


Correct Option: A
Explanation:

Poor T-cell responses specific for the leprosy bacillus, prevent the host from mounting a killing response and the bacilli grow profusely.

Which of the following characterises interferons?

  1. Opsonize viruses

  2. Neutralise viruses

  3. Play a major role in recovery from viral infections

  4. Prevent viral entry into cells

  5. Protect against reinfection with virus


Correct Option: C
Explanation:

Interferon inhibits the intracellular replication of viruses.

The HIV nef protein affects antigen presentation by which of the following?

  1. Causing MHC class I endocytosis.

  2. Containing glycine-alanine repeats, which inhibit proteasome-mediated processing of the virus.

  3. Preventing peptide binding to TAP.

  4. Preventing peptide transport through the TAP pore.

  5. Competing for peptide binding to the MHC class I heavy chain.


Correct Option: A
Explanation:

It thereby prevents effective presentation of antigen peptides to the T-cell receptor.

Which of the following is INCORRECT regarding blood coagulation in human beings?

  1. Platelets are the fragments of megakaryocytes.

  2. Primary haemostasis initially involves vasodailation.

  3. Platelet activation stimulates production of thromboxane.

  4. Fibrin monomers gets cross-linked by factor XIIIa.

  5. Clotting is initiated by exposure of tissue factor-bearing cells to plasma clotting factors.


Correct Option: B
Explanation:

Primary haemostasis initially involves vasoconstriction in response to vascular damage, which limits blood loss, and subsequent platelet adhesion to the damaged area and activation due to exposure of subendothelial matrix.

In a human male the origin of the blood supply to the penis is ____________.

  1. the uterine artery

  2. internal pudendal arteries

  3. pampiniform plexus

  4. genitofemoral artery

  5. superior mesenteric artery


Correct Option: B
Explanation:

The internal pudendal arteries serve as the penile blood supply by entering the penis dorsally and running deep into the tissues of the corpora cavernosa. The internal pudendal artery becomes the penile artery.

- Hide questions