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Kingdom Monera

Description: This test will help the learning aspirants to revise the above mentioned topic thoroughly.
Number of Questions: 15
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Tags: Bacteria Kingdom - Monera Classification of Prokaryotic Organisms
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Mr. Sethi is suffering with diseased heart valves. Which of the following causative agents can be a risk factor for him to cause endocarditis?

  1. Staphylococcus aureus

  2. Viridans Streptococci

  3. Streptococcus pyogenes

  4. Streptococcus pneumoniae

  5. Streptococcus bovis


Correct Option: B
Explanation:

Most of the α-hemolytic streptococci present in the normal flora are known as viridans because they cause green hemolysis on blood agar plates. It causes endocarditis generally in persons with diseased heart valves.

Community-acquired urinary tract infection (CA-UTI) is the most common infection caused by extended-spectrum β-lactamase. Which of the following is a causative agent of community-acquired UTIs?

  1. Klebsiella

  2. Pseudomonas aeruginosa

  3. Proteus mirabilis

  4. Acinetobacter

  5. Salmonella


Correct Option: C
Explanation:

Proteus mirabilis causes up to 10% of community-acquired UTIs and presumably colonises the normal human gastrointestinal tract.

Clostridium perfringens produces a potent toxin known as collagenase. This toxin is an example of __________.

  1. endotoxins

  2. membrane damaging toxins

  3. toxins that act on 28S rRNA

  4. toxins which act extracellularly.

  5. exotoxins


Correct Option: D
Explanation:

These include proteases, collagenases and hyaluronidases. For example, Clostridium perfringens produces a potent collagenase, whilst Staphylococcus aureus produces a hyaluronidase.

Anita's grandson is suffering from meningitis, which is a severe disease of CNS, being caused by meningococci bacteria. The mode of transmission of this bacteria is ____________.

  1. vehicle transmission

  2. vector transmission

  3. airborne transmission

  4. droplet transmission

  5. contact transmission


Correct Option: D
Explanation:

Droplet transmission involves coughing, sneezing  resulting in a spray of secretions capable of contacting conjunctiva, nasal mucosa and lips within a 3-foot radius. This is an important means of transmission of meningococci, influenza viruses and pertussis.

Mrs. Verma delivered a female baby. But after examining the baby, the paedeatrician confirmed that the baby was suffering from septicemia. Which of the following bacterias is responsible for neonatal meningitis and septicemia?

  1. Streptococcus viridans

  2. Streptococcus agalactiae

  3. Enterococci

  4. Streptococcus mutans

  5. Streptococcus pyogenes


Correct Option: B
Explanation:

These organisms causes neonatal meningitis and septicemia after transmission from the normal vaginal flora of the mother. The organism can be identified on the basis of beta hemolysis.

Which of the following species of E. coli is responsible for outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) worldwide?

  1. Enteropathogenic E. coli (EPEC)

  2. Enterotoxigenic E. coli (ETEC)

  3. Enteroinvasive Escherichia coli (EIEC)

  4. Enterohemorrhagic E. coli (EHEC)

  5. Enteroaggregative E. coli (EAggEC)


Correct Option: D
Explanation:

Enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 is a human pathogen responsible for outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) worldwide.

Which of the following statements regarding the pathogenesis of rickettsiae is INCORRECT?

  1. Rickettsiae grow free in the cytoplasm of cultured cells.

  2. Rickettsiae gets propelled by the host cell cytoplasm.

  3. Propulsion by F-actin helps in the spread of rickettsiae to adjacent endothelial cells.

  4. Growth of rickettsiae in the endothelium leads the damage of vascular integrity of an individual.

  5. Fusion of lysosomes with thrombocytes results in the digestion of dying rickettsia.


Correct Option: E
Explanation:

Gamma interferon and tumor necrosis factor alpha secreted by host immune cells activates the infected endothelial cell to destroy intracellular rickettsiae by the creation of autophagosomes. Later, fusion of lysosomes with autophagosomes results in the digestion of dying rickettsia  .

Which of the following dermal conditions is characterised by large numbers of cells including macrophages, lymphocytes and fibroblasts?

  1. Granuloma

  2. Granuloma annulare

  3. Granuloma faciale

  4. Fish bowl granuloma

  5. Gangrene


Correct Option: A
Explanation:

Granuloma is a chronic inflammatory lesion characterised by large numbers of cells of various types including macrophages, lymphocytes, fibroblasts, giant cells and some degrading and some repairing the tissues.

Which of the following is the causative agent for gastric and duodenal ulcers?

  1. Yersinia entercolitica

  2. Shigella flexneri

  3. Helicobacter pylori

  4. Campylobacter jejuni

  5. Vibrio parahemolyticus


Correct Option: C
Explanation:

It is a gram-negative, spiral to pleomorphic, prokaryote. H. pylori infection is the main cause of chronic superficial gastritis and it is associated with both gastric and duodenal ulcers.

Bacteremia is the presence of viable bacteria in the circulating blood. Which of the following is a common cause of bacteremia in human beings?

  1. C. botulinum

  2. C. difficile

  3. C. tetani

  4. B. fragilis

  5. P. aeruginosa


Correct Option: E
Explanation:

Infections by P. aeruginosa are a common cause of bacteremia that is bacterial blood infections. Heart valves, particularly of intravenous drug users can also become infected. Symptoms include general malaise with fever, joint and muscle pain.

Many factors play direct and indirect roles in Y. pestis pathogenesis. Which of the following factors are essential for rodent pathogenesis?

  1. Coagulase and Plasminogen activator

  2. Envelope (F-1) antigen

  3. Yops

  4. V and W proteins

  5. Low calcium response


Correct Option: C
Explanation:

A group of 11 proteins, which are coded by plasmids, are essential for rodent pathogenesis and are responsible for cytotoxicity, inhibition of phagocyte migration and engulfment and platelet aggregation.

Which of the following is a vector borne disease, where ticks primarily act as vector for humans?

  1. Erysipeloid

  2. Tularemia

  3. Listeriosis

  4. Anthrax

  5. Brucellosis


Correct Option: B
Explanation:

 Francisella tularensis is the causative agent of tularemia. Primary reservoirs are rabbits, hares and ticks. Man most commonly acquires tularemia via insect bites (ticks primarily, but also deer flies, mites, blackflies, or mosquitoes) or by handling infected animal tissues.  

Which of the following bacteriasare found as an intra-cellular agent within protozoa and a component of biofilms?

  1. H. influenzae

  2. B. pertussis

  3. Legionella pneumophila

  4. C. psittaci

  5. C. pneumoniae


Correct Option: C
Explanation:

Legionella pneumophila facultative intracellular pathogens, which stain poorly as Gram negative rods. It resides in the environment in pools of stagnant water worldwide. It is found as an intra-cellular agent within protozoa and a component of biofilms.

After medical check up, the doctor told the couple that their six month old baby is having a severe bacterial infection of a gram positive bacteria. Which of the following is a Gram-positive anaerobic rod which infects through skin abrasion in humans?

  1. Brucella

  2. Yersinia pestis

  3. L.monocytogenes

  4. Francisella tularensis

  5. Erysipelothrix rhusiopathiae


Correct Option: E
Explanation:

Erysipelothrix rhusiopathiae, is a Gram-positive anaerobic rod, which infects through skin abrasion while handling contaminated animal products or soil. Generally, the organism produces an inflammatory skin lesion, on fingers or hand, which is violaceus and has a raised edge. It spreads peripherally, as the discolouration in the central area fades.

HLA B27 is an inherited gene marker associated with a number of related rheumatic diseases. Which of the following diseases is associated with HLA-B27?

  1. Reiter's syndrome

  2. Lymphogranuloma venereum

  3. Inclusion conjunctivitis

  4. Trachoma

  5. Lymphogranuloma venereumis


Correct Option: A
Explanation:

Reiter's syndrome is a triad of symptoms that include conjunctivitis, polyarthritis and genital inflammation. The disease is associated with HLA-B27.

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