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Biochemistry

Description: Amino acids
Number of Questions: 15
Created by:
Tags: Amino acids Biotechnology
Attempted 0/15 Correct 0 Score 0

Which of the following statements is correct about physical properties of water? a. The heat of sublimation of ice is lower that heat of fusion. b. Boling points of H2O and CH4 are same as their molecular weight is same.c. Water at 0oC has a distance of 2.82-Å in neighbor molecules and 2.76-Å in ice form.

  1. Only a

  2. Only b

  3. Only 3

  4. Both a and b

  5. All of the above


Correct Option: C
Explanation:

Although the density of water is more, the molecular distances are larger in 0oC liquid water.

Which of the following statements is/are correct about amino acids?

  1. Alanine, valine, leucine, and isoleucine have aromatic hydrocarbon side chains.
  2. Methionine has a thiol ether side chain that resembles an n-butyl group in many of its physical properties.
  3. Proline has conformational constraints imposed by the cyclic nature of its pyrrolidine side chain.
  1. Only 1

  2. Only 2

  3. Only 3

  4. Both 2 and 3

  5. All of the above


Correct Option: D
Explanation:

Both option 2 and 3 are correct.

Which of the following annotations on chemical nature of amino acids is/are correct?

  1. Phenylalanine has indole group.
  2. Tryptophan has phenyl group.
  3. Tyrosine has phenol group.
  1. Only 1

  2. Only 2

  3. Only 3

  4. Both 1 and 2

  5. All of the above


Correct Option: C
Explanation:

This statement is correct.

Which of the following options is the correct order of dipole moment and dielectric constant of the following solvents?

  1. Dipole moment: Formamide > Water > Ethanol > Carbon tetrachloride; Dielectric constant: Formamide > Water > Ethanol > Carbon tetrachloride

  2. Dipole moment: Water > Formamide > Ethanol > Carbon tetrachloride; Dielectric constant: Water > Formamide > Ethanol > Carbon tetrachloride

  3. Dipole moment: Formamide > Water > Ethanol > Carbon tetrachloride; Dielectric constant: Formamide < Water < Ethanol < Carbon tetrachloride

  4. Dipole moment: Formamide < Water < Ethanol < Carbon tetrachloride; Dielectric constant: Formamide > Water > Ethanol > Carbon tetrachloride

  5. Dipole moment: Formamide < Water < Ethanol < Carbon tetrachloride; Dielectric constant: Formamide < Water < Ethanol > Carbon tetrachloride


Correct Option: A
Explanation:

This is the correct order of dipole moment and dielectric constant.

Which of the following amino acids have uncharged polar amide side chains?

  1. Serine 2. Threonine 3. Asparagine 4. Glutamine 5. Tyrosine
  1. 1 and 2

  2. 2 and 3

  3. 3 and 4

  4. 4 and 5

  5. 1 and 5


Correct Option: C
Explanation:

These have uncharged polar amide side chain.

Which of the following amino acids and the characters are correctly matched?

  1. cysteine: charged: thiol group 2. lysine: uncharged: butylammonium side chain 3. arginine: uncharged: guanidino group 4. histidine: uncharged: imidazolium group
  1. Only 1

  2. Both 1 and 2

  3. Only 3

  4. Both 3 and 4

  5. None of these


Correct Option: E
Explanation:

These all matches are incorrect in terms of their charge.

Which of these statements is/are correct about operational classification of amino acids based on optical activity?

  1. Dextrorotatory rotate the plane of plane-polarised light clockwise.
  2. Levorotatory rotate the plane of plane-polarised light anticlockwise
  3. Dextrorotatory and levorotatory molecules are assigned negative and positive values, respectively.
  1. Only 1

  2. Only 2

  3. Only 3

  4. Only 1 and 2

  5. All of the above


Correct Option: D
Explanation:

Yes, statement 1 and 2 are correct.

Which of the following statements about the Fischer convention of amino acids nomenclature is/are correct?

  1. This configuration system of the groups was introduced about an asymmetric center of aspirin.
  2. Horizontal bonds extend above and vertical bonds extend below the plane of the paper.
  3. All amino acids derived from proteins have the L-stereochemical configuration.
  1. Only 1

  2. Only 2

  3. Only 3

  4. Both 1 and 2

  5. Both 2 and 3


Correct Option: E
Explanation:

Both statements 2 and 3 are correct.

Which of the following statements about some uncommon amino acid residues is/are correct?

  1. Amino acid residues- 4-hydroxyproline and 5-hydroxylysine are important structural constituents of collagen.
  2. Histones have specifically methylated, acetylated, and/or phosphorylated Lys, Arg and Ser residues.
  3. N-formylmethionine is initially the N-terminal residue of all prokaryotic proteins.
  4. Gamma-carboxyglutamic acid is a constituent of several proteins involved in blood clotting.
  1. Only 1

  2. Only 2 and 3

  3. Only 3 and 4

  4. Only 2, 3 and 4

  5. All of the above


Correct Option: E
Explanation:

All these statements are correct.

Which of these statements about Cahn–Ingold–Prelog system of amino acids nomenclature is/are correct?

  1. Atoms of higher atomic number bonded to a chiral center are ranked below those of lower atomic number.
  2. The order of priority of these functional groups is: SH < OH < NH2. 3. The order of priority of these functional groups is: CH2OH < C6H5 < CH3.
  1. Only 1

  2. Only 2

  3. Only 3

  4. All of the above

  5. None of these


Correct Option: E
Explanation:

None of the statements is correct.

Find the correct match of amino acid residue with its function.

  1. Gamma-aminobutyric acid: a glutamatedecarboxylation product: neurotransmitters
  2. Dopamine: tyrosine derivative: fatty acid metabolism intermediate
  3. Histamine: histidine decarboxylation product: local mediator of allergic reactions
  4. Thyroxine: a tryptophan derivative: an iodine-containing thyroid hormone
  1. Only 1

  2. Only 1 and 3

  3. Only 4

  4. Only 2

  5. All of the above


Correct Option: B
Explanation:

Both these statements are correct.

Certain amino acids are important intermediates in various metabolic processes. A is an intermediate in urea biosynthesis, B is an intermediate in amino acid metabolism, C is a biological methylating reagent, D is an antibiotic and E is a neurotransmitter.

  1. A: citrulline

  2. B: ornithine

  3. C: homocysteine

  4. D: thyroxine

  5. E: beta-cyanoalanine


Correct Option: A
Explanation:

This is the correct choice.

Which of the following systems is/are not a nucleotide database?

  1. GenBank
  2. DDBJ
  3. EMBL
  4. DNASTAR
  1. Only 1

  2. Only 2

  3. Only 3

  4. Only 4

  5. None of these


Correct Option: D
Explanation:

DNASTAR is a bioinformatics software company, headquartered in Madison. WI develops desktop computer software for DNA, RNA and protein sequence analysis, including sanger and next generation sequence assembly.

Which of the following statements about thalidomide is/are correct?

  1. It was widely used in Europe as a mild laxtive in the early 1960s.
  2. Its active enantiomer causes severe birth defects in humans.
  3. Its effect is most dangerous during the last trimester of pregnancy.
  4. It was often prescribed to alleviate nausea (morning sickness) that is common during pregnancy.
  1. Only 1

  2. Only 2

  3. Only 3

  4. Only 4

  5. All of the above


Correct Option: D
Explanation:

This statement is correct.

What is the correct order of ion mobility of the following ions in an aqueous solution?

  1. Cation: H3O+ > Li+ > Na+, Anion: OH- > Br- > CH3COO-

  2. Cation: H3O+ > Na+ > Li+, Anion: OH- > Br- > CH3COO-

  3. Cation: Na+ > Li+ > H3O+, Anion: OH- > Br- > CH3COO-

  4. Cation: H3O+ > Li+ > Na+, Anion: CH3COO- > Br- > OH-

  5. Cation: H3O+ > Na+ > Li+, Anion: Br- > OH-> CH3COO-


Correct Option: B
Explanation:

This is the correct order of movement of anions and cations in an aqueous solution.

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