Heat shock proteins are class III molecules of the immune system.

Neutrophils are not involved anywhere in IgE mediated hypersensitivity. Type 3 hypersensitivity is mediated by neutrophils.

Increase in WBC count along with inflammation of the blood vessels is seen in Churg-Strauss syndrome (CSS). The inflammation of blood vessels can restrict blood flow to vital organs and tissues, sometimes permanently damaging them.

When type B blood is given to a person with type A blood, B Ag from the donor reacts with anti-B ab in the recipient. Complement is fixed and the red blood cells are lysed. Person with type A blood possesses type B antibodies. When type B blood is given to a person with type A blood, it causes lysis.

Skin lesions appear 24 hrs after second exposure. 

Diffuse scleroderma can cause musculoskeletal, pulmonary, gastrointestinal, renal and other complications. Raynaud's phenomenon is observed in diffuse scleroderma. Raynaud's phenomenon causes excessive reduced blood flow in response to cold or emotional stress, discolouration of the fingers, toes and occasionally other areas.

Complement activation in blood vessels causes basophils to granulate, which causes vasodilation.

Type 2 hypersensitivities involve interactions of surface antigens of cells followed by complement assisted lysis of cells. Mismatched blood transfusion is an example of type 2 hypersensitivity. On the basis of antigens on the cell surface, there are 4 blood groups and incompatibility exists if the blood containing different Ag is given.

MHC class I presents epitopes to killer T-cells, also called cytotoxic T lymphocytes (CTLs).

Enzymes responsible for peptide generation in MHC-I pathway are cytosolic proteosomes.

Anergy is a term in immunobiology that describes a lack of reaction by the body's defense mechanism to foreign substances. It consists of a direct induction of peripheral lymphocyte tolerance.

Schaumann bodies are observed in sarcoidosis. Schaumann bodies are calcium and protein inclusions inside Langhans giant cells (fused epithelial cells) as part of granuloma.

Lymphoplasmacytic sclerosing pancreatitis (LPSP) is seen in type 1 autoimmune pancreatitis.

Membranous nephropathy is an immune complex disease, so it is wrong to call it cytotoxic disease.

MHC class I occurs in all nucleated cells, except RBCs.