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Principles of Inheritance and Variation (Class - XII)

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Chiasmata formation in Drosophila

  1. generally takes place in males and females

  2. takes place only in males

  3. never or rarely takes place in males

  4. never or rarely take place in females


Correct Option: C
Explanation:

In Drosophila, the situation is very different.

In which of the following crosses will the progenies obtained be fifty percent homozygous recessive and fifty percent heterozygous?

  1. TT x Tt

  2. Tt x Tt

  3. Tt x tt

  4. TT x tt


Correct Option: C
Explanation:

In this condition the progenies obtained will be fifty percent homozygous recessive and fifty percent heterozygous.

‘Gametes are never hybrid’. It is a statement of the law of

  1. dominance

  2. segregation

  3. independent assortment

  4. random fertilisation

  5. linkage


Correct Option: B
Explanation:

‘Gametes are never hybrid’. It is a statement of law of segregation. 

A Barr body is present in a male child. The syndrome most likely to occur is

  1. Klinefelter’s syndrome

  2. Down’s syndrome

  3. Turner's syndrome

  4. Edward’s syndrome

  5. Trisomy


Correct Option: A
Explanation:

A normal female with XX chromosomes has one Barr body. A normal male (XY) has none. Abnormal males with three XXY (Klinefelters' syndrome) have one Barr body.

A cross between yellow round and green wrinkled seed pea plants gave the following four types of progeny in equal proportions: yellow round, yellow wrinkled, green round and green wrinkled. The genotypes of the parents in this case must be

  1. YYRR X yyrr

  2. YyRr X yyrr

  3. YYRR X YYRR

  4. YyRr X YYRR

  5. yyrr X yyrr


Correct Option: B
Explanation:

YyRr X yyrr produces yellow round, yellow wrinkled, green round and green wrinkled progeny.

Sex-influenced genes are coded by

  1. autosomal genes

  2. X linked genes

  3. Y linked genes

  4. epistatic genes

  5. none of the above


Correct Option: A
Explanation:

Sex-influenced traits are autosomal traits that are influenced by sex.

Phenylketonuria is a genetic disorder of

  1. trisomic condition

  2. monosomic dominant gene

  3. autosomal dominant gene

  4. autosomal recessive gene

  5. None of these


Correct Option: D
Explanation:

Phenylketonuria (PKU) is a caused due to mutation in gene on chromosome 12.Gene codes for phenylalanine hydroxylase that breaks phenylalanine into other products.

When chromosome sets are present in multiples of ‘n’, the condition is called

  1. polyploidy

  2. aneuploidy

  3. euploidy

  4. diploidy

  5. monoploidy


Correct Option: C
Explanation:

When chromosome sets are present in multiples of ‘n’, the condition is called euploidy.

Which of the following chromosome numbers is present in a trisomic individual?

  1. 2n + 1

  2. 2n - 1

  3. 2n - 2

  4. 2n + 2


Correct Option: A
Explanation:

This indicates that there is an extra chromosome in the diploid.

Loss of one chromosome from one set is called

  1. tetrasomy

  2. nullisomy

  3. monosomy

  4. trisomy


Correct Option: C
Explanation:

It is the loss of one chromosome from a set.

The addition or deletion of one or more chromosomes in a set is called

  1. euploidy

  2. aneuploidy

  3. polyploidy

  4. heteroploidy


Correct Option: B
Explanation:

It is the state of having abnormal number of chromosomes.

What would a gene be called if it is inherited by both males and females, but expressed differently in the phenotype of a boy and a girl?

  1. Unstable

  2. Sex-controlled

  3. Recessive

  4. Structural

  5. Dominant


Correct Option: B
Explanation:

A gene would be called sex controlled if it is inherited by both males and females, but expressed differently in the phenotype of a boy and a girl.

Drosophila flies with XXY genotype are females, but human beings with such genotype are abnormal males. It shows that

  1. Y-chromosome is essential for sex determination in Drosophila

  2. Y-chromosome is female determinator in Drosophila

  3. Y-chromosome is male determinator in human beings

  4. Y-chromosome has no role in sex determination either in Drosophila or in human beings

  5. None of the above


Correct Option: C
Explanation:

In human beings, the presence of a Y-chromosome is required for the development of a male sex phenotype. In human beings, the presence of a Y-chromosome is required for the development of a male sex phenotype.

Assertion (A): In Klinefelter’s syndrome, the chromosomal constitution of man is 22AA + XXY. Reasoning (R): Few men have XX karyotype and yet are males. This is a rare phenomenon due to translocation of a small segment of Y chromosome attached to an X chromosome and is inherited in concert with X. Choose the correct option for the above statements.

  1. Both Assertion and Reasoning are true and R is the correct explanation of A.

  2. Both Assertion and Reasoning are true and R is not the correct explanation of A.

  3. A is true and R is false.

  4. Both A and R are false.

  5. A is false and R is true.


Correct Option: A
Explanation:

In Klinefelter’s syndrome, the chromosomal constitution of man is 22AA + XXY.Few men have XX karyotype and yet are males. This is a rare phenomenon due to translocation of a small segment of Y chromosome attached to an X chromosome and is inherited in concert with X. In Klinefelter’s syndrome, the chromosomal constitution of man is 22AA + XXY.Few men have XX karyotype and yet are males. This is a rare phenomenon due to translocation of a small segment of Y chromosome attached to an X chromosome and is inherited in concert with X.

The genotypic ratio in a monohybrid cross is

  1. 3 : 1

  2. 9 : 3 : 3 : 1

  3. 2 : 2 : 1

  4. 1 : 2 : 1

  5. 2 : 1 : 3


Correct Option: D
Explanation:

This is the correct option.

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