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Vitamins (Medical Entrance)

Description: Proteins
Number of Questions: 40
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Tags: vitamins Importance and Deficieny Symptoms of Vitamins
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Which vitamin is found abundantly in mushrooms?

  1. Vitamin D1

  2. Vitamin D5

  3. Vitamin D3

  4. Vitamin D2


Correct Option: D
Explanation:

Alfalfa and mushrooms are the good sources of vitamin D2. About 13.1 mcg of vitamin D2 is present in mushroom portobello and 4.8 mcg in alfalfa. 

The active form of which vitamin is a coenzyme that takes part in the conversion of pyruvate to acetyl CoA?

  1. Pyridoxine

  2. Riboflavin

  3. Thiamine

  4. Cobalamin


Correct Option: C
Explanation:

Active form of Thiamine is a coenzyme called thiamine pyrophosphate (TPP), which takes part in the conversion of pyruvate to acetyl coenzyme A (CoA) in metabolism.

Vitamin C is also known as

  1. D-ascorbic acid

  2. L-ascorbic acid

  3. oxalic acid

  4. tocopherol


Correct Option: B
Explanation:

Vitamin C is also known as L-ascorbic acid. Most of the functions of L-ascorbate as a vitamin relies not on its antioxidant properties.

Which vitamin enhances the absorption of calcium, iron, magnesium, phosphate and zinc?

  1. Vitamin K

  2. Vitamin A

  3. Vitamin D

  4. Vitamin B12


Correct Option: C
Explanation:

Vitamin D enhances the absorption of calcium, iron, phosphate, magnesium and zinc. Thus, it is important for the health of bones.

Which of the following organisms do not synthesise ascorbate (vitamin C) internally?

  1. Guinea pigs

  2. Pigs

  3. All bats

  4. Rats


Correct Option: A
Explanation:

Guinea pigs cannot synthesise ascorbate internally. It has to be taken in from an external source.

Which hormone-like substance acts as a growth factor for epithelial cells?

  1. Retinal

  2. Retinoic acid

  3. Retinol

  4. Rhodopsin


Correct Option: B
Explanation:

Retinoic acid is a hormone-like substance that acts as a growth factor for epithelial cells. It is an irreversibly oxidised form of retinol.

Which vitamin serves as a cofactor in biosynthesis of neurotransmitters?

  1. Vitamin B6

  2. Vitamin B7

  3. Vitamin B9

  4. Vitamin B12


Correct Option: A
Explanation:

The active form of vitamin B6, i.e. pyridoxal 5'-phosphate serves as a cofactor in biosynthesis of neurotransmitters.

The deficiency of which vitamin is linked to neural tube defect in early embryo development?

  1. Cyanocobalamin

  2. Folic acid

  3. Niacin

  4. Pantothenic acid


Correct Option: B
Explanation:

Vitamin B9 (folic acid) deficiency in early embryo development has been linked to neural tube defects.

Which of the following groups of compounds is known as vitamin E?

  1. Ascorbates

  2. Phylloquinone

  3. Tocopherols

  4. Secosteroids


Correct Option: C
Explanation:

Vitamin E belongs to a group of compounds called tocopherols.

In which form is vitamin A stored in the human body?

  1. Retinal

  2. Retinol

  3. Alpha carotene

  4. Retinoic acid


Correct Option: B
Explanation:

Vitamin A is stored in the human body in the form of retinol and can be converted to and from its visually active aldehyde form, retinal.

A person's vitamin D status can be determined by measuring the serum concentration of

  1. Calcidiol and Cholecalciferol

  2. Calcitriol and Ergocalciferol

  3. Calcidiol and 25-hydroxyergocalciferol

  4. Calcitriol and 25-hydroxyergocalciferol


Correct Option: C
Explanation:

A person's vitamin D status is determined by measuring the serum concentration of Calcidiol and 25-hydroxyergocalciferol.

Which of the following species of birds lacks the ability to carry out the biosynthesis of vitamin C?

  1. Pencaea

  2. Passerine

  3. Palecanus

  4. Parorcomyza


Correct Option: B
Explanation:

Passerines lack the ability to carry out the biosynthesis of vitamin C. These birds have lost the ability to synthesise vitamin C with time.

Which vitamin plays a major role in electron transport chain?

  1. Vitamin B5

  2. Vitamin B2

  3. Vitamin B3

  4. Vitamin B6


Correct Option: B
Explanation:

Vitamin B2, i.e. riboflavin, is involved in energy production for the electron transport chain.

Which form of vitamin K is toxic to humans?

  1. Vitamin K4

  2. Vitamin K3

  3. Vitamin K2

  4. Vitamin K5


Correct Option: B
Explanation:

Vitamin K3 is a synthetic form of vitamin K, which is toxic to humans.

Which of the following contains the least amount of vitamin A?

  1. Sweet potato

  2. Cod liver oil

  3. Milk

  4. Cheddar cheese


Correct Option: C
Explanation:

Milk contains 28 micrograms of vitamin A per 100 grams. Thus, it contains the least amount of vitamin A.

What was the nucleobase called adenine earlier known as?

  1. Vitamin K3

  2. Vitamin B4

  3. Vitamin B17

  4. Vitamin P


Correct Option: B
Explanation:

Adenine was earlier known as vitamin B4. It is a nucleobase synthesised by the human body.

Which of the following acts as a coenzyme form of vitamin B3?

  1. Nicotinamide

  2. Nicotinic acid

  3. NADP

  4. Niacin


Correct Option: C
Explanation:

NADP, i.e. nicotinamide adenine dinucleotide phosphate, is a coenzyme form of vitamin B3.

Directions: Read the information given below and answer the question that follows:

The classic clinical syndrome is a seborrhoeic dermatitis-like eruption, atrophic glossitis with ulceration, angular cheilitis, conjunctivitis, intertrigo, and neurologic symptoms of somnolence, confusion and neuropathy.

The deficiency of which vitamin is explained in the passage given above?

  1. Thiamine

  2. Pyridoxine

  3. Biotin

  4. Pantothenic acid


Correct Option: B
Explanation:

The classic clinical syndrome for vitamin B6 (pyridoxine) deficiency is a seborrhoeic dermatitis-like eruption, atrophic glossitis with ulceration, angular cheilitis, conjunctivitis, intertrigo, and neurologic symptoms of somnolence, confusion and neuropathy.

Which of the following functions is performed by biotin?

  1. Conversion of pyruvate to acetyl CoA

  2. Acts as a coenzyme for acetyl-CoA carboxylase

  3. Beta-oxidation of fatty acids

  4. Metabolism of nucleic acids


Correct Option: B
Explanation:

Biotin is a critical coenzyme for acetyl CoA carboxylase, which is involved in the synthesis of fatty acids from acetate.

Which sub type of vitamin K is synthesised by human tissues?

  1. Menaquinone-4 (MK-4)

  2. Menaquinone-7 (MK-7)

  3. Menaquinone-9 (MK-9)

  4. Menaquinone-8 (MK-8)


Correct Option: B
Explanation:

Menaquinone-7 is not produced by human tissues. MK-7 may be converted from phylloquinone (K1) in the colon by E. coli bacteria.

The deficiency of which of the following vitamins can lead to carboxylase deficiency?

  1. Pyridoxal

  2. Biotin

  3. Niacin

  4. Folic acid


Correct Option: B
Explanation:

Deficiency of biotin leads to carboxylase deficiency. It is a form of metabolic disorder involving the failure of carboxylation enzymes.

Which of the following is/are the richest source of vitamin K1?

  1. Spinach

  2. Collards

  3. Mustard greens

  4. Kale


Correct Option: D
Explanation:

Cooked kale is the richest source of vitamin K1. 1/2 cup of kale contains 531 micrograms of vitamin K1.

Which of the following is the richest source of vitamin C?

  1. Blueberry

  2. Kakadu plum

  3. Indian gooseberry

  4. Camu camu


Correct Option: B
Explanation:

Kakadu plum is the richest source of vitamin C. It contains 1000-5300 mg of vitamin C/1000 g of its serving.

Which of the following is an inherited disorder of fat metabolism that results in poor absorption of dietary fat and vitamin E?

  1. Pancreatic insufficiency

  2. Abetalipoproteinmia

  3. Crohn's disease

  4. Spinocerebellar ataxia


Correct Option: B
Explanation:

Abetalipoproteinmia is a rare autosomal recessive disorder that interferes with the normal absorption of fat and fat-soluble vitamins like vitamin E. It is an inherited disorder.

The deficiency of which vitamin causes scoliosis, lordosis and dark skin colouration in fishes?

  1. Choline

  2. Vitamin B1

  3. Vitamin C

  4. Vitamin K


Correct Option: C
Explanation:

Vitamin C deficiency causes scoliosis, lordosis and dark skin colouration in fishes. Scoliosis refers to deformity in spinal cord and lordosis refers to the inner curvature of the spinal cord.

Which vitamin acts as an antioxidant in the glutathione peroxide pathway?

  1. α-Tocopherol

  2. Tocotrienol

  3. γ-Tocopherol

  4. I isomer of tocotrienol


Correct Option: A
Explanation:

α-Tocopherol functions as an antioxidant in the glutathione peroxidase pathway, and it protects cell membranes from oxidation by reacting with lipid radicals produced in the lipid peroxidation chain reaction.

Which derivative of vitamin A is used in skin creams?

  1. Retinoid

  2. Retinoic acid

  3. Retinyl palmitate

  4. Retinol


Correct Option: C
Explanation:

Retinyl palmitate is used in skin creams, where it is broken down to retinol and metabolised to retinoic acid, which has potent biological activity.

Which of the following were respectively the first and the last vitamins to be discovered?

  1. Vitamin A and Vitamin B9

  2. Vitamin A and Vitamin B1

  3. Vitamin C and Vitamin D

  4. Vitamin A and Vitamin B3


Correct Option: A
Explanation:

Vitamin A and Vitamin B9 were the first and the last vitamins discovered, respectively. Vitamin A was discovered in 1913 and vitamin B9 was discovered in 1941.

Which of the following is the most abundant in vitamin E?

  1. Peanut oil

  2. Wheat germ oil

  3. Almond oil

  4. Sunflower oil


Correct Option: B
Explanation:

Wheat germ oil contains 215.4 mg of vitamin E per 100 grams of the oil. Out of the four options, wheat germ oil is most abundant in vitamin E.

What is the tolerable upper limit level of folic acid?

  1. 1 mg/day

  2. 35 mg/day

  3. 1000 mg/day

  4. No limit


Correct Option: A
Explanation:

The tolerable upper limit level of folic acid is 1 mg/day. Higher levels can lead to permanent neurological damage.

Which of the following vitamins aids in erythropoisis?

  1. Biotin

  2. Folic acid

  3. Pantothenic acid

  4. Niacin


Correct Option: B
Explanation:

The coenzyme form of folic acid, i.e. tetrahydofolate, aids in erythropoisis, i.e. production of red blood cells.

Hypervitaminosis of which vitamin can cause pseudotumor cerebri syndrome?

  1. Vitamin D

  2. Vitamin E

  3. Vitamin A

  4. Vitamin B12


Correct Option: C
Explanation:

Hypervitaminosis of vitamin A can cause pseudotumor cerebri syndrome. This syndrome has symptoms like headache, blurring of vision and confusion, associated with increased intracerebral pressure.

Which supplement can alleviate the chronic vitamin K deficiency caused by long-term aspirin use?

  1. Vitamin K1

  2. Vitamin K2

  3. Vitamin K3

  4. Vitamin K4


Correct Option: B
Explanation:

Vitamin K2 (menaquinone) is not inhibited by salicylates, so menaquinone supplementation can alleviate the chronic vitamin K deficiency caused by long-term aspirin use.

Which vitamin is responsible for the expression of connective tissue growth factor (CTGF)?

  1. Vitamin E

  2. Vitamin A

  3. Vitamin D

  4. Vitamin B3


Correct Option: A
Explanation:

Alpha tocopherol, i.e. vitamin E, induces the expression of connective tissue growth factor, which modulates and coordinates signalling responses involving cell surface proteoglycans.

Craniotabes is the sign of deficiency of

  1. vitamin K

  2. vitamin D

  3. vitamin E

  4. vitamin C


Correct Option: B
Explanation:

Craniotabes is caused by vitamin D deficiency in children. Craniotabes is seen mostly in the occipital and parietal bones. The bones become soft and when pressure is applied on them, they will collapse underneath it. When the pressure is relieved, the bones usually snap back into place.

Which of the following vitamins acts as a cofactor in the synthesis of collagen?

  1. Vitamin E

  2. Vitamin A

  3. Vitamin C

  4. Vitamin B1


Correct Option: C
Explanation:

Vitamin C acts as a cofactor in the synthesis of collagen. Its dysfunction results in scurvy.

Arrange the following in the decreasing order of amount of vitamin C present in them:

Beef liver, calf liver, lamb liver, pork liver

  1. Calf liver, lamb liver, beef liver, pork liver

  2. Calf liver, beef liver, pork liver, lamb liver

  3. Lamb liver, pork liver, beef liver, calf liver

  4. Lamb liver, calf liver, beef liver, pork liver


Correct Option: B
Explanation:

This is in decreasing order. Calf liver contains 36 mg of vitamin C per 100 g, beef liver contains 31 mg of vitamin C per 100 g, pork liver contains 23 mg of vitamin C per 100 g and lamb liver contains 12 g of vitamin C per 100 g.

Which vitamin aids in the binding of proteins to calcium ions for bones?

  1. Vitamin E

  2. Vitamin K

  3. Vitamin B

  4. Vitamin A


Correct Option: B
Explanation:

Vitamin K is needed for the complete synthesis of certain proteins that the body uses to control the binding of calcium in bones and other tissues.

Hypervitaminosis E is associated with the deficiency of

  1. vitamin C

  2. vitamin K

  3. vitamin A

  4. vitamin B-complex


Correct Option: B
Explanation:

Hypervitaminosis E is associated with the risk of vitamin K deficiency. This results in bleeding problems.

Match the columns:

 
Side A Side B
1. Vitamin B1 a. CoA
2. Vitamin B2 b. NAD
3. Vitamin B3 c. Citric acid cycle
4. Vitamin B5 d. RNA and DNA replication
  1.  
    1. Vitamin B1 c.Citric acid cycle
    2. Vitamin B2 a. CoA
    3. Vitamin B3 d. RNA and DNA replication
    4. Vitamin B5 b. NAD
  2.  
    1. Vitamin B1 a. CoA
    2. Vitamin B2 b. NAD
    3. Vitamin B3 c. Citric acid cycle
    4. Vitamin B5 d. RNA and DNA replication
  3.  
    1.Vitamin B1 d. RNA and DNA replication
    2. Vitamin B2 c. Citric acid cycle
    3. Vitamin B3 b. NAD
    4. Vitamin B5 a. CoA
  4.  
    1. Vitamin B1 b. NAD
    2. Vitamin B2 d. RNA and DNA replication
    3.Vitamin B3 a. CoA
    4. Vitamin B5 c. Citric acid cycle

Correct Option: C
Explanation:

This is the correct match. Vitamin B1 is involved in RNA and DNA production; vitamin B2 is involved in citric acid cycle; NAD is a coenzyme form of vitamin B3; CoA can be synthesised from vitamin B5.

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