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Infections and Diseases (GATE)

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Which of the following is a pair of diseases caused by Gram-positive bacteria?

  1. Gonococcal urethritis and Hansen’s coccus spirilly

  2. Cholera and Botulism

  3. Hansen’s coccus spirilly and Listeriosis

  4. Gonococcal urethritis and Cholera

  5. Gonococcal urethritis and Listeriosis


Correct Option: C
Explanation:

This option is correct because Hansen’s coccus spirilly is a disease caused by a Gram-positive bacterium Mycobacterium tuberculosis and Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes (Gram-positive bacterium).

Which of the following diseases are caused by Gram-positive spore-forming bacteria?

P. Typhoid Q. Lockjaw R. Cryptococcosis S. Anthrax

  1. P and Q

  2. P and R

  3. Q and R

  4. Q and S

  5. R and S


Correct Option: D
Explanation:

This option is correct because anthrax is an infectious disease caused by a Gram-positive, spore-forming rod-shaped bacterium Bacillus anthracis and lockjaw is an infectious disease caused by the anaerobic Gram-positive, spore-forming bacterium Clostridium tetani.

Which of the following viral diseases are caused by double-stranded DNA viruses?

P. Morbilli Q. Epidemic parotitis R. Varicella S. Red plague

  1. P and Q

  2. P and R

  3. Q and R

  4. Q and S

  5. R and S


Correct Option: E
Explanation:

Varicella is caused by the varicella zoster virus (VZV), an enveloped double-stranded DNA virus, and red plague is caused by the variola virus, a double-stranded DNA virus of the Poxviridae family.

In which of the following autoimmune diseases do the medium-sized blood vessels throughout the body become inflamed?

  1. SARS

  2. Hepatitis B

  3. Lymph node syndrome

  4. Plague

  5. Bull neck


Correct Option: C
Explanation:

Lymph node syndrome (Kawasaki disease) is an autoimmune disease in which the medium-sized blood vessels throughout the body become inflamed.

Which of the following diseases is/are caused by rod-shaped Gram-negative bacteria?

  1. Pertussis
  2. Pneumococcal pneumonia
  3. Diphtheria
  1. Only 1

  2. Only 2

  3. Only 3

  4. 1 and 2

  5. 2 and 3


Correct Option: A
Explanation:

Pertussis is caused by Bordetella pertussis, a small rod-shaped Gram-negative bacterium.

Which among the following infections spreads through vaginal intercourse, oral-to-genital contact, and vertically from mother to her infant in utero?

  1. Herpes

  2. Micoplasma hominis

  3. Crypto

  4. Shigellosis

  5. Giardiasis


Correct Option: B
Explanation:

Micoplasma hominis infection spreads through vaginal intercourse, oral-to-genital contact, and vertically from mother to her infant in utero or by the colonization by the bacteria as the baby descends through the birth canal or by nosocomial acquisition through transplanted tissues.

Which of the following viral diseases mainly affects brain?

  1. Rabies

  2. Yellow fever

  3. Hepatitis B

  4. Q fever

  5. Influenza


Correct Option: A
Explanation:

In rabies, the main part of the body that is mostly affected is brain, particularly the central nervous system.

Which of the following infectious diseases is caused by a partially double-stranded DNA virus?

  1. Hepatitis A

  2. Hepatitis B

  3. Hepatitis C

  4. Hepatitis D

  5. Hepatitis E


Correct Option: B
Explanation:

Hepatitis B is an infectious illness of the liver caused by the hepatitis B virus. Hepatitis B virus is a DNA virus and is enveloped. The DNA is only partly double-stranded and forms a circle of around 3200 bases.

Which of the following is a sexually transmitted infection in humans caused by bacterium Treponema pallidum and transmitted from mother to fetus during pregnancy or at birth?

  1. Gonnococcal infection

  2. Trichomoniasis

  3. Syphilis

  4. Chlamydia infection

  5. Herpes simplex


Correct Option: C
Explanation:

Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis.

Which of the following is an acute inflammation of the protective membranes covering the brain and spinal cord?

  1. Rabies

  2. Meningitis

  3. Anthrax

  4. Epilepsy

  5. Migraine


Correct Option: B
Explanation:

Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. The inflammation may be caused by infection with viruses, bacteria or other microorganisms, and less commonly by certain drugs.

Match the column – I (disease) with column – II (causative agent) and select the correct option.

 
Column – I Column – II
A. Syphilis 1. Protozoan
B. Croup 2. Bacteria
C. Thrush 3. Fungus
D. Cryptosporidium 4. Virus
  1. A - 1, B - 2, C - 3, D - 4

  2. A - 1, B - 4, C - 2, D - 3

  3. A - 2, B - 4, C - 3, D - 1

  4. A - 2, B - 3, C - 4, D - 1

  5. A - 4, B - 1, C - 2, D - 3


Correct Option: C
Explanation:

Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. Croup is a respiratory condition that is usually triggered by an acute viral infection of the upper airway. Thrush is a fungal infection caused by yeasts that belong to the genus Candida. Cryptosporidiosis is a parasitic disease caused by Cryptosporidium, a protozoan parasite in the phylum Apicomplexa.

Which among the following is a neurodegenerative genetic disorder that affects muscle coordination and leads to mental decline and behavioural symptoms?

  1. Huntington's disease

  2. Arachnoid cysts

  3. Tropical spastic paraparesis

  4. Encephalitis

  5. Alzheimer's


Correct Option: A
Explanation:

Huntington's disease is a neurodegenerative genetic disorder that affects muscle coordination and leads to mental decline and behavioral symptoms. Symptoms of the disease can vary between individuals and affected members of the same family, but usually progress predictably.

Match the following:

   
Disease Causative agent Vector
P. Dumdum fever i. Flavivirus spp. 1. Tse-tse fly
Q. African trypanosomiasis ii. Leishmania donovani 2. Sand fly
R. Jail fever iii. Trypanosoma brucei 3. Mosquito
S. Yellow plague iv. Rickettsia prowazekii 4. Body louse
  1. P - ii - 3, Q - iv - 1, R - i - 2, S - iii - 4

  2. P - iii - 1, Q - iv - 2, R - ii - 4, S - i - 3

  3. P - i - 2, Q - ii - 4, R - iii - 2, S - iv - 3

  4. P - ii - 2, Q - iii - 1, R - iv - 4, S - i - 3

  5. P - i - 4, Q - iii - 1, R - ii - 3, S - iv - 2


Correct Option: D
Explanation:

This option is correct because all are correctly matched. Dumdum fever is caused by Leishmania donovani and transmitted by the bite of the sand fly. African Trypanosomiasis is caused by Trypanosoma brucei and transmitted by the tse-tse fly. Jail fever is caused by Rickettsia prowazekii and transmitted by the human body louse (Pediculus humanus corporis). Yellow plague is a mosquito-borne infectious disease of humans and other animals caused by parasites of the Flavivirus spp.

 

Match the column – I with column – II and select the correct option.

 
Column – I Column – II
P. Hookworm 1. Ancylostoma duodenale
Q. Pinworm 2. Ascaris lumbrcoides
R. Roundworm 3. Enterobius vermicularis
S. Whipworm 4. Trichuris trichiura
  1. P - 1; Q - 2; R - 3; S - 4

  2. P - 1; Q - 3; R - 2; S - 4

  3. P - 2; Q - 4; R - 3; S - 1

  4. P - 2; Q - 3; R - 4; S - 1

  5. P - 4; Q - 3; R - 2; S - 1


Correct Option: B
Explanation:

This option is correct because all are correctly matched. Ancylostoma duodenale is a species of the worm genus Ancylostoma. It is a parasitic nematode worm and commonly known as Old World hookworm. The pinworm (Enterobius vermicularis) is a small parasitic worm that can live inside the human lower intestine. Ascaris lumbricoides is the giant roundworm of humans, belonging to the phylum Nematoda. The human whipworm (Trichuris trichiura) is the third most common roundworm found in humans.

 

Match the entries in column – I and column – II and select the correct option.

 
Column – I Column – II
A. Lung fluke 1. Paragonimus westermani
B. Intestinal fluke 2. Fasciolopsis buski
C. Liver fluke 3. Fasciola hepatica
4. Ancylostoma duodenale
  1. A - 1, B - 2, C - 3

  2. A - 3, B - 1, C - 4

  3. A - 4, B - 2, C - 3

  4. A - 2, B - 1, C - 3

  5. A - 4, B - 2, C - 1


Correct Option: A
Explanation:

This option is correct because Paragonimus westermani is a lung fluke and is most prominent in Asia and South America, intestinal fluke (Fasciolopsis buski), which causes faciolopsiasis, is the largest intestinal fluke of humans and Fasciola hepatica (also known as common liver fluke or sheep liver fluke) is a parasitic flatworm of the class Trematoda, phylum Platyhelminthes.

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