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Human Physiology

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In humans, the vitreous gel

  1. contains 98% water

  2. is acellular

  3. contains mainly type II and type III collagen fibres

  4. has a refractive index of 1.00


Correct Option: A
Explanation:

The vitreous humor is a clear jelly-like liquid filling the cavity of the eye. 98-99% of its volume is water. All the blood vessels are absent in it.

Aversive conditioning is a technique in which something unpleasant is used to stop an unwanted behaviour of an individual. Which of the following senses is strongly affiliated with aversive conditioning?

  1. Vision

  2. Pressure

  3. Taste

  4. Balance


Correct Option: C
Explanation:

Aversive conditioning is the use of something unpleasant or a punishment to stop an unwanted behaviour. It is mainly associated with taste of an organism.

Impulses originated in the taste buds of the tongue cover their journey through the cerebral cortex via

  1. thalamus

  2. internal capsule

  3. trochlear nerve

  4. hypoglossal nerve


Correct Option: A
Explanation:

It lies between the cerebral cortex and midbrain. Its prominent function includes relaying sensory and motor signals to the cerebral cortex, along with the regulation of consciousness, sleep and alertness. Impulses originated in the taste buds of the tongue cover their journey through the cerebral cortex via. thalamus.

Which of the following structures leads to the eardrum?

  1. Pinna

  2. Eustachian tube

  3. Semicircular canals

  4. Cochlea


Correct Option: A
Explanation:

The pinna is the outermost part of the ear composed of cartilage and being connected to the outer tube called the auditory canal. This leads to the eardrum.

Which structure originates from the second pharyngeal arch?

  1. Incus

  2. Stylohyoid muscle

  3. Internal maxillary artery

  4. Posterior one-third of the tongue


Correct Option: B
Explanation:

It is a facial muscle located in the neck. It is thin and slender and is attached to the hyloid bone. It derives from the second pharyngeal arch.

Which of the following statements is correct regarding the conduction system of human heart?

  1. Between action potentials, the cells of the SA node have a steady resting potential.

  2. The cardiac action potential reaches both the atrium with the help of Purkinje fibers.

  3. The Purkinje fibers are particularised cardiac myocytes conjoined by gap unions.

  4. The diffusion of cardiac excitation accelerates at the AV node.


Correct Option: C
Explanation:

This is the correct statement. In ventricles, the specialised conducting cells are the bundle cells and the Purkinje fibers, which transmit their action potentials to the ventricular myocytes via gap junctions.

Which of the following statements is correct regarding the normal heart sound in a healthy person?

  1. The first heart sound, i.e. lub corresponds to the closure of mitral and tricuspid valves.

  2. The first heart sound, i.e. lub occurs just before the R wave of the ECG.

  3. The first heart sound, i.e. lub splits into two components during inspiration.

  4. The second heart sound i.e .dub occurs during the T-wave.


Correct Option: A
Explanation:

Since the first heart sound (lub) is caused by closure of the atrio-ventricular valves, it must occur after the onset of ventricular contraction, which follows the R wave.

The cardiac output

  1. increases by the hormone aldosterone released from the adrenal medulla

  2. increases by stimulation of the vagus nerve

  3. is calculated as the ratio of oxygen consumption and the difference in PO2 of the venous and arterial blood

  4. is mainly actuated by the end-diastolic volume of the blood


Correct Option: D
Explanation:

Cardiac output is the volume of blood pumped by the heart per minute. It is mainly determined by the end-diastolic volume of the blood.

The blood circulation is under the control of nervous system. Which one is true regarding the nervous regulation of the circulation?

  1. Baroreceptors are authorative for the long-term regulation of systemic blood pressure.

  2. If the arterial pressure of a person suddenly falls, the baroreceptor reflex accelerates the heart rate.

  3. The baroreceptors lie in the aortic and carotid bodies.

  4. The coronary blood flow is controlled by the cardiac volume receptors.


Correct Option: B
Explanation:

This statement is correct. The most important function of the baroreceptor reflex is to stabilize perfusion pressure in the face of disturbances of circulatory homeostasis.

Blood platelets are also known as thrombocytes. Which of the following statements is correct regarding the blood platelets?

  1. They are present in greater number than RBCs.

  2. They release the main clotting factors in the blood.

  3. They attach to the walls of damaged blood vessels.

  4. They conjoin in the presence of prostacyclin.


Correct Option: C
Explanation:

In case of injury, the damaged endothelial cells lining the blood vessel release von Willebrand's Factor which makes the surfaces sticky. The platelets start adhering to the surfaces of endothelial cells. This effect is called platelet adhesion.

Which of the following is correct regarding the control of the vasculature?

  1. Autoregulation signifies to nervous control of the blood vessels.

  2. Reactive hyperemia originates as a result of vasodilatation caused by accumulation of metabolites during exercise.

  3. Parasympathetic vasodilator fibers activate the blood vessels of the exocrine glands of the gastrointestinal tract.

  4. The diameter of the arterioles is completely regulated by the sympathetic nervous system only.


Correct Option: C
Explanation:

Parasympathetic vasodilator fibers pertain to the craniosacral division of the autonomic nervous system. These fibers activate the blood vessels of the exocrine glands of the gastrointestinal tract.

'Microcirculation' is the flow of blood through the smallest vessels of the body. Which among the following characterises microcirculation?

  1. The exchange of solutes among the capillaries and body tissues occurs mainly through mass flow.

  2. The capillaries act as vital source of vascular resistance.

  3. All of the fluid circulating through the capillaries to the tissues is returned to the blood through the lymphatic circulation.

  4. The plasma proteins play key role in tissue fluid exchange mechanism.


Correct Option: D
Explanation:

This statement is correct. Plasma is the pale yellow coloured liquid part of blood and carries dissolved substances such as glucose and other products of digestion, hormones, vitamins, etc. Thus, it plays key role in tissue fluid exchange mechanism.

In humans, the red blood cells

  1. are secreted into the circulation as immature cells known as reticulocytes

  2. have life span of about 10 days

  3. depend on mitochondria for their ATP synthesis

  4. are formed by budding off megakaryocytes


Correct Option: A
Explanation:

This statement is correct. Reticulocytes are young, anucleate red blood cells,  which are released from bone marrow into the blood in increased numbers as a response to anemia.

During the cardiac cycle of a normal healthy adult, which of the following events takes place?

  1. During ventricular diastole, the pressure in the left ventricle of heart reaches upto the maximum value of 80 mm Hg.

  2. During ventricular systole, the pressure in the left ventricle of heart reaches up to a maximum value of about 120 mm Hg.

  3. The increase in the rate of pressure is determined by excitation-contraction coupling.

  4. During ventricular systole, the total blood present in the ventricles is ejected.


Correct Option: D
Explanation:

It is just the reverse statement. During the time period between the closure of the AV valves and the opening of the aortic and pulmonic valves, ventricular pressure rises rapidly without a change in ventricular volume. Thus, no ejection of blood occurs.

Which of the following statements referring to transport of the gases by the blood is correct?

  1. Exiting from the lungs, each litre of blood carries about 2 ml of oxygen.

  2. Haemoglobin is half saturated with oxygen when the PO2 is about 3.3 kPa and PCO2 is 5.3 kPa.

  3. As the PCO2 rises, the compatibility of hemoglobin for oxygen increases.

  4. Each litre of arterial blood contains about 5 mL of carbon dioxide.


Correct Option: B
Explanation:

The primary function of hemoglobin is to transport oxygen. When half of the sites are filled with oxygen, the blood is said to be 50% saturated. This happens when the PO2 is about 3.3 kPa and PCO2 is 5.3 kPa.

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