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Human Physiology

Description: This test is based on certain topics of biology which are highly beneficial for learning aspirants.
Number of Questions: 25
Created by:
Tags: Embryogenesis Foetus gametogenesis contraceptives etc Embryonic Development Pregnancy and Parturation Parturition and Lactation Pregnancy and Parturition Structure of Reproductive System Male Reproductive System Menstrual Cycle
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Which of the following is an event associated with the fetal circulation?

  1. The fetal heart rate is about double that of a healthy adult.

  2. All the blood present in the umbilical vein enter the left ventricle.

  3. Two of the embryo shunts close just after the parturition.

  4. Fetal blood pressure is higher than that of an adult.


Correct Option: A
Explanation:

It is true that fetal heart rate is faster than an adult heart rate, which ranges from 100 -140 beats per minute. Changes in the fetal heart rate, which occur with contractions, form a pattern. Baby's heart rate increases with mother's movement and with uterine contractions.

Which of the following statements is correct regarding respiration in the fetus and newborn?

  1. The peripheral chemoreceptors are well functional in the developing embryo and in a newborn.

  2. In the newborn, complete output of the right ventricle is sent to the lungs.

  3. Deficiency of surfactant in the newborn has no effect on respiration.

  4. The first breath in a newborn is associated with numerous modulation in the intrathoracic pressure.


Correct Option: D
Explanation:

The newborns first breath the lungs, which were filled with fluid during pregnancy. The lungs must suddenly fill with oxygen from the air. The fluid in the lungs is removed through the blood and lymph system, and is replaced by air. At the same time, vigorous blood circulation in the lungs begins.

Which of the following statements is true concerning the function of the fetal adrenal glands and kidneys?

  1. Fetal corticoids stimulate the production of pulmonary surfactant by alveolar type II cells.

  2. The fetal zone of the adrenal gland produces huge amount of testosterone.

  3. The regulation of acid-base balance of the fetus is govern by the kidneys.

  4. The fetal kidneys starts producing a hypertonic urine after about 6 to 8 weeks of gestation.


Correct Option: C
Explanation:

It is the correct statement. In foetus, the kidney participates in whole-body homeostasis regulating acid-base balance, electrolyte concentrations and extracellular fluid volume.

Which of the following characterises the sexual development of the fetus?

  1. The sex of the developing embryo is determined by a single gene present on the Y chromosome.

  2. In the absence of a Y chromosome, the sexual development of the developing embryo will fail to follow any pattern.

  3. The maturation of the fetal gonads into the female type are initiated in the presence of estrogens.

  4. The sex of the developing embryo is determined by the set of genes on the Y chromosome.


Correct Option: A
Explanation:

A single gene on the Y, called SRY, triggers testes development in the early embryo and once these begin to form, the rest of the embryo also becomes male. Thus, the sex of the developing embryo is determined by a single gene present on the Y chromosome.

Which of the following signifies the oxygen transport by fetal blood?

  1. In a developing embryo, the blood bouncing back to the umbilical vein is completely saturated with O2.

  2. Fetal hemoglobin has a higher compatibility for oxygen than adult hemoglobin.

  3. In a normal foetus, the blood has a lower hemoglobin content than adult blood.

  4. Blood reaching the brain of a fetus has the same PO2 as that of blood in the descending aorta.


Correct Option: B
Explanation:

This is the correct answer. Fetal blood has a higher hemoglobin content than adult blood and fetal hemoglobin has a higher affinity for O2 than adult hemoglobin. Therefore, O2 content of blood in the umbilical vein is about 160 ml/l.

Which of the following statements is true regarding the sexual reflexes and fertilization in humans?

  1. Erection in males is a sympathetic reflex.

  2. During ejaculation, the sperms are mixed with secretions from the prostate and seminal vesicles.

  3. In females, the fertilization occurs in the uterus.

  4. Fertilization may occur two or more days after ovulation.


Correct Option: B
Explanation:

Semen is a viscous whitish secretion of the male reproductive organs during ejaculation containing spermatozoa and consisting secretions of the testes, seminal vesicles, prostate, and bulbourethral glands.

Which among the following is the main function of the placenta?

  1. The placenta nourishes the developing embryo by implementing a dialysis pattern for exchange between the maternal and fetal circulations.

  2. The placental barrier is highly permeable to glucose and amino acids.

  3. The PO2 of the blood of the umbilical vein in the developing embryo is the same as that in the maternal arterial blood.

  4. The estrogens secreted by the placenta during pregnancy decelerates.


Correct Option: A
Explanation:

Placenta is the first organ to develop when blastocyst embeds itself. Nutrients diffuse into the umbilical cord at the placenta that then pass through the ammnionic sac into the fetus. Thus, the placenta nourishes the developing embryo by the dialysis pattern.

Which of the following events occurs during pregnancy?

  1. In a pregnant lady, the plasma hCG levels are the highest between weeks 8 and 10 of gestation.

  2. Placental progesterone secretion is the highest in the first 10 to 12 weeks of gestation.

  3. Blood flow to the kidneys decreases to maintain the pregnancy.

  4. Maternal respiratory rate increases for supplying oxygen to the developing embryo.


Correct Option: A
Explanation:

In a pregnant lady, the plasma hCG levels are the highest between weeks 8 and 10 of gestation as the hCG is secreted by the early embryo.

Which is the correct statement with reference to the control of lactation in a nursing mother?

  1. In a nursing mother, the prolactin stimulates milk ejection .

  2. Placental steroid secretion decelarates lactation during pregnancy.

  3. In a nursing mother, the vasopressin is secreted in response to suckling.

  4. In a nursing mother, the oxytocin secretion can be suppressed by dopamine agonists.


Correct Option: B
Explanation:

This statement is correct. The placental steroid secretion decelarates lactation during pregnancy in order to maintain the pregnancy.

Which of the following statements characterises the sexual reproduction in humans?

  1. A mature human sperm contains a complete set of chromosomes.

  2. Primary spermatocytes divide by mitosis to give rise to spermatids.

  3. At parturition, an ovary contains all the oocytes it will ever have.

  4. The sperm is known as male zygotes.


Correct Option: C
Explanation:

This is the correct answer. At birth, a human ovary contains about 2,00,000 eggs. They are enclosed in a single layer of cells called the primordial follicles. The ovaries do not produce any more egg. Women are born with all of the eggs they ever have.

Which of the following statements regarding the hormonal control of the menstrual cycle is correct?

  1. The myometrium propagates under the strict control of FSH.

  2. The estrogens are produced predominantly by the cells of the theca interna.

  3. After ovulation, the ruptured follicle gets transformed into a corpus albicans that secretes progesterone.

  4. Progesterone promotes full development of the endometrium.


Correct Option: D
Explanation:

It is the correct answer. Progesterone promotes thickening of the uterine lining and inhibits the anterior pituitary from secreting FSH.

Which among the following statements is TRUE regarding the salivary secretion and swallowing in human beings?

  1. The segmentation movements propel down the bolus .

  2. The pH of saliva in the buccal cavity accelerates as its rate of secretion increases.

  3. Hormones play more significant role than nerves in the governing of salivary secretion.

  4. Swallowing in humans is a totally voluntary activity.


Correct Option: B
Explanation:

As salivary secretion increases, so does its bicarbonate concentration. This results in an increase in salivary pH.

During the ovarian cycle, the first part of the menstrual cycle is known as the follicular phase. The luteal phase follows ovulation. The initial recruitment of primordial follicles into the preantral phase is hormone independent. Which of the following statements?

  1. The beggining phase of the menstrual cycle is known as the luteal phase.

  2. The initiation of the preantral phase of follicular development is under the control of two hormones named as LH and FSH.

  3. The advancement of the antral follicle is predicated on the expression of receptors for FSH and LH.

  4. Ovulation occurs to reciprocate a sudden increase in plasma FSH.


Correct Option: C
Explanation:

During the preantral phase, the follicular cells acquire receptors for various hormones. The granulosa cells develop receptors for FSH and estrogen while the thecal cells acquire receptors for LH.

Select the CORRECT statement regarding the control of gastric secretion in humans.

  1. Parietal cells of the gastric glands secrete gastric acid in response to hormonal stimulation.

  2. In an individual, most of the acid and pepsinogen released by the stomach takes place during the intestinal phase of gastric secretion.

  3. Gastric secretion does not commence unless the bolus reaches the stomach of an individual..

  4. Secretin being released by the duodenum stimulates gastric secretion in the stomach.


Correct Option: A
Explanation:

Parietal cells produce gastric acid, a strong acid that helps to break down food. These cells produce gastric enzymes such as pepsinogen and lipase, which helps us to digest.

Which among the following statements is TRUE for gastric motility?

  1. Gastric emptying is restricted by the enterogastric reflex.

  2. The fundus region of the stomach is important for the storage of food.

  3. Contractions of the stomach wall do not begin unless the bolus enters the stomach.

  4. The contractions of the stomach depend on activity in the sciatic nerve.


Correct Option: A
Explanation:

The enterogastric reflex is a general term, which is used to describe all the hormonal and nervous mechanisms that control gastric emptying.

Which of the following statements is correct regarding pancreatic secretion of the body?

  1. Pancreatic secretion is restricted by gastrin being secreted by the G cells of the antrum.

  2. Pancreatic acinar cells accomodate trypsin.

  3. Cholecystokinin restricts secretion from the exocrine pancreas.

  4. The commencement of acid into the duodenum stimulates pancreatic secretion.


Correct Option: D
Explanation:

This statement is correct.  Acid in contract with the duodenal wall causes the secretion of secretin, which stimulates a copious alkaline secretion by the cells of the pancreatic ducts.

Bile is a bitter, alkaline, brownish-yellow secreted by the liver. Which of the following statement is correct for bile?

  1. It gets diluted in the gall bladder of an individual.

  2. Hepatic bile salts act as hydrophobic molecules.

  3. Maximum bile salts are reabsorbed in the terminal ileum.

  4. Bile salts are the end products of hemoglobin present in the blood.


Correct Option: C
Explanation:

Most bile salts are reabsorbed in the terminal ileum and returned to the liver by the enterohepatic circulation.

Which of the following statements is correct regarding the major dietary constituents?

  1. The human body cannot store glucose.

  2. All essential amino acids are found in meat.

  3. Plant oils primarily consist of saturated fats.

  4. Normally ketones are found in the urine of a person eating a carbohydrate rich diet.


Correct Option: B
Explanation:

Animal protein is complete protein and contains all 20 amino acids, which are used by the body to synthesize new proteins.

Which of the following statements is correct regarding the dietary requirements of the major foodstuffs by an individual?

  1. Adults can synthesize all of the essential amino acids in their bodies.

  2. Children serving with a protein deficient diet may develop kwashiorkor.

  3. Edema is a particular feature of marasmus.

  4. An individual taking a diet low in fats often suffers from fatty acid deficiency diseases.


Correct Option: B
Explanation:

Children whose diet is protein deficient are at a risk of developing kwashiorkor.

Which of the following statements is correct regarding the digestion and absorption by the small intestine of an individual?

  1. Intestinal digestive enzymes are secreted by cells of the oxyntic cells.

  2. Approximately 50% of the digested carbohydrate is absorbed in the small intestine.

  3. Small peptides are absorbed in the small intestine.

  4. The liver is the first organ of the digestive system to receive the digestion products of dietary fats.


Correct Option: C
Explanation:

This is the correct answer. There is no absorption of peptide longer than four amino acids. However, there is great absorption of di- and tripeptides in the small intestine. These small peptides are absorbed into small intestinal epithelial cell by co-transport with H+ ions through a transporter called PepT1.

Referring to gastro-intestinal function of an individual, which of the following events occurs in the body?

  1. The presence of enormous fat in the chyme will speed up gastric emptying.

  2. Distension of the ileum triggers gastric motility.

  3. Total gastrectomy leads to malabsorption of vitamin B12 in the body .

  4. Aldosterone restricts the absorption of sodium and water by the large intestine in the digestive system.


Correct Option: C
Explanation:

Intrinsic factor secreted by the parietal cells of the gastric glands is needed for the absorption of vitamin B12.

Which of the following statements is TRUE regarding the vitamins?

  1. Excess intake of vitamin A leads to severe toxic reactions in the body.

  2. Vitamin B2 deficiency leads to severe muscular disorders in an individual.

  3. Vitamin B12 deficiency causes microcytic anemia in females.

  4. Rickets in adults can be prevented by large doses of vitamin D.


Correct Option: A
Explanation:

This is the correct statement. Excess vitamin A is highly toxic and can cause a variety of neurological problems.

The cells helping an individual to detect surface like rough vs. smooth are

  1. Schwann cells

  2. Pacinian corpuscles

  3. Kulchitsky cells

  4. Merkel cells


Correct Option: B
Explanation:

These are mechanoreceptor. They are nerve endings present in the skin which are responsible for perception to vibration and pressure. Vibrational role is used by an individual to detect surface like rough vs. smooth.

Which among the following characterises the events taking place in the testis?

  1. Sertoli cells allow the unrestrained diffusion of water-soluble substances between the seminiferous tubules and the blood.

  2. Leydig cells secrete testosterone

  3. Sertoli cells reciprocate to testosterone by synthesising androgen binding protein.

  4. Sertoli cells line the seminiferous tubules and boost the developing sperm in males.


Correct Option: B
Explanation:

As a consequence of stimulation with luteinizing hormone, the interstitial cells (Leydig) secrete testosterone into the intertubular tissue, where it is absorbed by blood vessels, lymphatics, and the seminiferous tubules.

Which of the following detects the tension deep in the skin?

  1. The Bulbous corpuscle

  2. Merkel's discs

  3. Pacinian corpuscles

  4. Meissner's corpuscles


Correct Option: A
Explanation:

It is a slow adopting mechanoreceptor. It detects tension deep in the skin.

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