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Biochemistry

Description: BIOCHEMISTRY 2
Number of Questions: 15
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Tags: BIOCHEMISTRY CELL Organization of Life
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Carbonic anhydrase is the vital respiratory enzyme present in red blood cells catalysing the interconversion of carbon dioxide (CO2) and carbonic acid (H2CO3), thus influencing CO2 transport in the blood. Which of the following elements is found to play an important mediator of the enzyme carbonic anhydrase?

  1. Copper

  2. Molybdenum

  3. Iron

  4. Zinc

  5. Manganese


Correct Option: D
Explanation:

Zinc plays a vital role as coenzyme or activator of various metabolic enzymes as in case of zinc-mediated role of the enzyme carbonic anhydrase.

Many drugs have been developed to treat AIDS (acquired immunodeficiency syndrome), caused by HIV (human immunodeficiency virus). The drugs are basically nucleoside reverse transcriptase inhibitors. Which of the following compounds is a famous anti-HIV drug?

  1. Abrin

  2. Amethopterin

  3. 6-mercaptopurine

  4. AZT

  5. Thymidine


Correct Option: D
Explanation:

AZT (Azido dideoxythymidine) also called zidovudine is an inhibitor of the usual RNA-directed DNA synthesis of the AIDS virus, and hence a famous anti-HIV drug.

Leuprolide is a well known hormonal analog and agonist. Which of the following hormonal actions is mimicked by Leuprolide?

  1. Glucocorticoid

  2. Gonadotropin-releasing hormone

  3. Epinephrine

  4. Aldosterone

  5. ACTH


Correct Option: B
Explanation:

Leuprolide is a well known gonadotropin-releasing hormone (GnRH) agonist  analog that is more potent than the natural hormone, GnRH. It has been useful in prostatic cancer treatment.

Macrophages are specialised phagocytic cells having immunological roles. Which of the following proteins is found in macrophages?

  1. Accelerin

  2. Ankyrin

  3. Gelsolin

  4. Villin

  5. Acumentin


Correct Option: E
Explanation:

Acumentin is a protein found in macrophages that binds to the minus end of actin filaments.

Spectrophotometer is an instrument that is made of a monochromator, composed of prisms and is used for the isolation of narrow band widths. Spectrophotometers help in measurement of the selective absorption of light and utilised in both qualitative and quantitative analysis of various molecules and chemicals. Which of the following compounds is a dye used for the spectrophotometric determination of proteins?

  1. Acriflavin

  2. Naphthol blue black

  3. Pyronin Y

  4. Methylene blue

  5. Agent orange


Correct Option: B
Explanation:

Naphthol blue black or amido black 10B is a well known dye used for the spectrophotometric determination of proteins.

Arthritis is a painful disorder of bone joints. It may be of acute and chronic pathological types. Which of the following analog of hypoxanthine is used in the treatment of acute inflammatory arthritis?

  1. 6-mercaptopurine

  2. Aminopterin

  3. Amethopterin

  4. Allopurinol

  5. Alpha amanitin


Correct Option: D
Explanation:

Allopurinol is an analog of hypoxanthine used to treat individuals suffering from hyperuricemia as a result of gout and other pathological conditions.

Various inhibitors are used in the study of the electron transport system at various levels of electron carriers. Which of the following substances acts as an inhibitor of the electron transport system between cytochromes b and c1?

  1. Antimycin A

  2. Azurin

  3. Bottromycin

  4. Amytal

  5. Atractyloside


Correct Option: A
Explanation:

Antimycin A is an antibiotic, produced by Streptomyces griseus that inhibits the electron transport system between cytochromes b and c1.

Monosaccharides and disaccharides are different forms of carbohydrates. Which of the following colorimetric tests helps us to distinguish monosaccharides from disaccharides?

  1. Acrolein test

  2. Anthrone test

  3. Barfoed's test

  4. Biuret reaction

  5. Carr-Price test


Correct Option: C
Explanation:

Barfoed's test is a colorimetric test for distinguishing mono - from disaccharides by means of a solution of cupric acetate in dilute acetic acid.

There are various known synthetic plant growth inhibitors that play similar roles as natural growth inhibitor hormones. Which of the following substances is an example of synthetic plant growth inhibitor?

  1. Indole butyric acid

  2. Morphactin

  3. Kinetin

  4. Naphthalene acetic acid

  5. Vernalin


Correct Option: B
Explanation:

Morphactin is a specialised synthetic plant growth regulator involved in morphogenesis of plants.

Cytokinins are vital plant growth hormones associated with cell division. Which of the following compounds represents the precursor for synthesis of cytokinin?

  1. Furfural

  2. Ent-kaurene

  3. Zeaxanthin

  4. Campesterol

  5. Tryptophan


Correct Option: A
Explanation:

Furfural represents the precursor for synthesis of cytokinin.

There are various chemical tests performed as a part of urine analysis. Which of the following tests helps us to determine the presence of protein in urine?

  1. Berthelot reaction

  2. Albustix test

  3. Allen's test

  4. Bang method

  5. Bradshaw test


Correct Option: B
Explanation:

Albustix test is a rapid and semi-quantitative test for the presence of protein in urine by means of paper strips impregnated with buffer and indicator.

An antidepressant refers to a stimulatory drug that reduces fatigue and appetite. Which of the following substances is used as an antidepressant?

  1. Amphetamine

  2. Barbiturates

  3. Aspartame

  4. Bentonite

  5. Cannabinoids


Correct Option: A
Explanation:

Antidepressants are usually amines such as amphetamine and ephedrine is that are believed to function as competitive inhibitors of monoamine oxidase. This leads to an accumulation of catecholamines, the natural substrates of the enzyme and results in stimulatory effects.

Auxins are vital phytohormones that play various roles in growth responses. Auxins may be either naturally occurring or synthetic compounds. Which of the following is an example of naturally occurring auxin?

  1. Naphthylphthalamic acid

  2. Parascorbic acid

  3. Indole butyric acid

  4. Vernalin

  5. Phenylacetic acid


Correct Option: E
Explanation:

Phenylacetic acid is an example of naturally occurring auxin.

Beta blockers are utilised as vital drugs. They are widely used to reduce the risk of heart attacks. Who among the following scientists was awarded the Nobel prize for his discovery of beta blockers as vital drugs?

  1. George Hitchings

  2. Paul Boyer

  3. J. Skou

  4. James Black

  5. Stanley Prusiner


Correct Option: D
Explanation:

James Black developed beta blockers that are used to reduce the risk of heart attacks.

The ‘anti-dermatitis factor’ is called so because of the fact that the problem of skin inflammation increased greatly when the concerned diet lacked this factor. Which of the following vitamins is popularly known as anti-dermatitis factor?

  1. Vitamin C

  2. Vitamin B1

  3. Vitamin B3

  4. Vitamin B6

  5. Vitamin B12


Correct Option: D
Explanation:

Vitamin B6 is popularly known as anti-dermatitis factor. The vitamin B6 was originally given the name of ‘anti-dermatitis factor’ due to the fact that the problem of skin inflammation increased greatly when the concerned diet lacked this vitamin.

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