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Gene Expression (Medical Entrance)

Description: protein
Number of Questions: 15
Created by:
Tags: protein Gene Expression and Regulation Regulation of Gene Expression
Attempted 0/15 Correct 0 Score 0

RNA polymerase I is required for the synthesis of

  1. mRNA

  2. tRNA

  3. rRNA

  4. DNA


Correct Option: C
Explanation:

rRNA is synthesised by RNA polymerase I.

What is the sequence of nucleotides in Pribnow box?

  1. ATATTA

  2. TATAAT

  3. UAUAAT

  4. TATAAA


Correct Option: B
Explanation:

The Pribnow box (also known as the Pribnow-Schaller box) is the sequence TATAAT of six nucleotides (thymine-adenine-thymine-etc.) that are essential parts of a promoter site on DNA for transcription to occur in bacteria.

Which of the following steps are involved in post transcriptional modification of pre-mRNA?

  1. 5' capping

  2. 3' polyadenylation

  3. RNA splicing

  4. All of the above


Correct Option: D
Explanation:

Post-transcriptional modifications of pre-mRNA involve 5'capping, 3' polyadenylation and RNA splicing.

Which of the following yields functional RNA as a gene product?

  1. Sn RNA

  2. t-RNA

  3. Both (1) and (2)

  4. m RNA


Correct Option: C
Explanation:

Both Sn RNA and t-RNA are non protein coding genes and yield functional RNA as products.

By which process does bacteriophage express its genes?

  1. Lysis

  2. Lysogeny

  3. Both (1) and (2)

  4. Transduction


Correct Option: C
Explanation:

Bacteriophages undergoes both lysis and lysogeny to express its genes.

Genes whose products are constantly needed for the maintenance of the cells are called

  1. inducible genes

  2. constitutive genes

  3. facultative genes

  4. housekeeping genes


Correct Option: D
Explanation:

A housekeeping gene is typically a constitutive gene that is transcribed at a relatively constant level. The housekeeping gene's products are typically needed for maintenance of the cell. It is generally assumed that their expression is unaffected by experimental conditions. Examples include actin, GAPDH and ubiquitin.

Which of the following enzymes play(s) a role in the liberation of phages?

  1. Ribozymes

  2. Lysozymes

  3. Reverse transcriptase

  4. DNA polymerase


Correct Option: B
Explanation:

Lysozymes synthesised by the phage, attack the wall of the bacteria, causing its lysis and liberation of phages.

What is nucleolus composed of?

  1. RNA

  2. Proteins

  3. RNA and proteins

  4. DNA


Correct Option: C
Explanation:

Nucleolus is composed of both RNA and proteins.

By which process is the phage transmitted to the progeny of bacteria?

  1. Transduction

  2. Liberation

  3. Induction of prophage

  4. Lysogeny


Correct Option: D
Explanation:

Phage is transmitted to the progeny of bacteria by lysogeny.

Gene expression by teminism is observed in

  1. ΦX174

  2. TMV (Tobacco Mosaic virus)

  3. RSV (Rous Sarcoma virus)

  4. mumps virus


Correct Option: C
Explanation:

RSV is a retrovirus and expresses gene by teminism.

Which process takes place in vegetative phase of lytic cycle?

  1. RNA replication

  2. DNA replication

  3. Enzyme synthesis

  4. Liberation of phages


Correct Option: B
Explanation:

Bacteriophages undergoes DNA replication within minutes of infecting bacteria. About 100 to 150 molecules are produced at this stage.

What is merozygote?

  1. Recombinant formed in transformation

  2. Combination of bacterial and temperate phage genome

  3. Temporary RNA-DNA diploid formed during reverse transcription

  4. Two bacteria joined by conjugation tube


Correct Option: A
Explanation:

The recombinant formed in transformation with slightly more amount of DNA is known as mrerozygote or partial zygote.

Gene expression in bacteria takes place by

  1. transformation

  2. transcription

  3. replication

  4. Both (3) and (2)


Correct Option: A
Explanation:

Gene expression in bacteria takes place by transformation. The donor DNA is broken into one gene segment which enters the recipient cell, gets integrated into recipient genome and expresses itself.

What is F-factor?

  1. Single-stranded RNA

  2. Double-stranded circular genomic DNA

  3. Single-stranded circular genomic DNA

  4. Double-stranded circular plasmid DNA


Correct Option: D
Explanation:

F-factor is a double-stranded plasmid DNA.

Who proposed that each gene in an organism controls the production of specific enzymes?

  1. Temin and Baltimore

  2. Jacob and Monad

  3. Beadle and Tatum

  4. Nirenberg and Khorana


Correct Option: C
Explanation:

Beadle and Tatum showed that each gene in an organism controls the production of specific enzymes.

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