Yes, it is the correct answer. Hemophila A is associated with episodes of bleeding. Current treatment involves infusion of factor VIII to promote blood clotting during a bleeding episode.

Yes, the inversion of part of gene cannot be detected . As it would not cause the exons to be absent or missing, and the sequencing reaction would not reveal that the exons are no longer arranged in the proper order on genomic DNA.

Yes, it is the correct answer. The Amsterdam criteria are used to assess risk of HNPCC to guide identification of individuals for whom genetic testing may be helpful.

Yes, it is the correct answer. HER-2/neu activation in breast cancer, the predominant genetic mechanism for oncogene activation is through an amplification of a gene. It is an important prognostic indicator.

Yes, it is the correct answer. Clinical validity refers to how well the genetic variant being analyzed is related to the presence, absence, or risk of a specific disease.

Yes, it is the correct answer. Polymorphism of the SCN7 gene is assocated with drug-induced cardiac arrhythmia.

The basement membrane is a thin sheet of fibers. It lies between the epidermis and dermis and keeps the outer layer adhered closely to the lower layer.

It is the outermost layer of the epidermis, consisting of dead and desquamating cells.

Yes, it is the correct answer. A pseudostratified columnar epithelium forms the linning of the respiratory tract and of the ducts in the male reproductive system.

Yes, it is the correct answer. RET mutation is responsible for increased risk of medullary thyroid cancer, as well as multiple endocrine neoplasia 2, in which pheochromocytoma and parathyroid adenoma also occur.

Yes, Pacinian corpuscles are simple nerve endings covered with multilamellar, ovoid structures resembling small onions. These corpuscles respond to deep pressure.

Yes, it is correct. Osteoblasts forms new bone lamellae. They are active in bone development and bone remodelling.

Yes, it is correct. Mast cells acts as a secretory alarm cells of the body. Upon the slightest disturbance, they release chemical signals which diffuse through the surrounding ground substance and stimulate the process of inflammation.

Yes, it is the correct answer.  Merkel cells are minute cells linked with nerve endings in epidermis. They are generally involved in neural encoding of tactile sensation.

Yes, it is the correct answer. The genes involved in risk of HNPCC are involved in the process of DNA mismatch repair.