Spider-Man 2, released in 2004, was a revolutionary superhero game that allowed players to freely explore Manhattan and engage in various missions and side activities, setting the standard for open-world superhero games.

The Joker, Batman's arch-enemy, is a central antagonist in the Batman: Arkham series, known for his chaotic and unpredictable nature.

Marvel's Guardians of the Galaxy, released in 2021, is known for its vibrant cel-shaded graphics and its emphasis on witty dialogue and humorous interactions between the characters.

Earth-22 is the alternate universe featured in the Injustice series, where Superman succumbs to grief and becomes a ruthless dictator after the death of Lois Lane.

Marvel Heroes, a now-defunct online action RPG, allowed players to create their own custom characters and team up with iconic Marvel superheroes to battle villains and explore various locations.

The Legion of Doom is the main antagonist organization in DC Universe Online, consisting of powerful supervillains who seek to conquer the world.

Marvel's Avengers includes a time-travel mechanic that allows players to revisit key moments in the game's story and make different choices, potentially altering the outcome of events.

The Arkham Knight is the primary antagonist in Batman: Arkham Knight, a mysterious figure who leads a militia of mercenaries and threatens to destroy Gotham City.

Infamous, released in 2009, features a morality system where players' actions and choices determine whether their character becomes a heroic or villainous figure.

Mr. Negative is the primary antagonist in Marvel's Spider-Man, a powerful crime lord who seeks to unleash a deadly virus upon New York City.

Gotham Knights, released in 2022, features a co-op mode where players can team up as Batgirl, Robin, Nightwing, or Red Hood to protect Gotham City from various threats.

The Brotherhood of Mutants, led by Magneto, is the primary antagonist organization in the X-Men Legends series, seeking to establish mutant supremacy over humans.

Marvel Ultimate Alliance 3: The Black Order features a unique combat system where players can control a team of four superheroes and seamlessly switch between them during battle.

Arkham City is the primary setting in Batman: Arkham City, a walled-off section of Gotham City that has been transformed into a massive prison complex.

Superman Returns, released in 2006, features an open-world environment where players can explore the city of Metropolis and interact with various characters from the Superman universe.