The Last Supper, painted by Leonardo da Vinci, portrays the final meal Jesus shared with his disciples before his arrest and crucifixion.

Michelangelo's depiction of God's finger touching Adam's fingertip represents the moment when God bestows life upon humanity.

Raphael's Sistine Madonna captures the tender bond between Mary and Jesus, emphasizing their divine and human aspects.

Caravaggio's use of chiaroscuro, with the dramatic lighting, serves multiple purposes: emphasizing the divine nature of the calling, highlighting the significance of the moment, and creating a visually striking composition.

The Ghent Altarpiece, a multi-paneled masterpiece, depicts the central theme of the Adoration of the Lamb, symbolizing the sacrifice and redemption brought by Jesus Christ.

Bosch's triptych, The Garden of Earthly Delights, is renowned for its vivid and fantastical imagery, often interpreted as a representation of the consequences of sin and the path to salvation.

El Greco's painting depicts the burial of Count Orgaz, with celestial figures representing the Holy Trinity, angels, and the ascent of Count Orgaz's soul, symbolizing the transition from earthly life to the afterlife.

Rembrandt's "The Night Watch" captures the moment when a militia company, led by Captain Frans Banning Cocq and Lieutenant Willem van Ruytenburch, prepares to march out.

Goya's "The Third of May 1808" depicts the execution of Spanish civilians by French soldiers during the Peninsular War, serving as a stark reminder of the brutality and senselessness of war.

The Mona Lisa's enigmatic smile has been the subject of much debate and speculation, contributing to its enduring fascination and mystique.

Van Gogh's "The Starry Night" is renowned for its expressive brushwork and vivid colors, capturing the artist's emotional turmoil and his connection to the natural world.

Michelangelo's "Pieta" captures the Virgin Mary's profound grief and sorrow over the death of her son, while also conveying her unwavering faith and acceptance of God's will.

Caravaggio's "Judith Beheading Holofernes" portrays the biblical story of Judith, a Jewish widow, who seduces and decapitates Holofernes, saving her people from his tyranny.

Raphael's "The School of Athens" places Plato and Aristotle in the center, emphasizing their pivotal roles in Western philosophy, their influence on Renaissance thinkers, and their harmonious relationship despite their contrasting ideas.

Jan van Eyck's "The Arnolfini Portrait" is renowned for its exquisite detail, realism, and use of oil paints, exemplifying the Early Netherlandish painting style.