Antigens and Their Recognition

Description: This quiz is designed to assess your understanding of antigens and their recognition by the immune system.
Number of Questions: 15
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Tags: immunology antigens immune recognition
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What is an antigen?

  1. A substance that triggers an immune response

  2. A type of white blood cell

  3. A protein produced by the immune system

  4. A type of antibody


Correct Option: A
Explanation:

An antigen is any substance that is recognized by the immune system and triggers an immune response.

What are the two main types of antigens?

  1. Exogenous and endogenous

  2. Humoral and cell-mediated

  3. Primary and secondary

  4. Active and passive


Correct Option: A
Explanation:

Exogenous antigens are those that enter the body from outside, while endogenous antigens are those that are produced inside the body.

What is the role of antigen-presenting cells (APCs) in the immune response?

  1. To phagocytize antigens and present them to T cells

  2. To produce antibodies against antigens

  3. To release cytokines that activate other immune cells

  4. To destroy infected cells


Correct Option: A
Explanation:

APCs are specialized cells that phagocytize antigens and present them to T cells, which are essential for the activation of the adaptive immune response.

What are the two main types of T cells involved in the immune response to antigens?

  1. Helper T cells and cytotoxic T cells

  2. Regulatory T cells and memory T cells

  3. Naive T cells and effector T cells

  4. Central T cells and peripheral T cells


Correct Option: A
Explanation:

Helper T cells help to activate other immune cells, while cytotoxic T cells kill infected cells.

What is the role of antibodies in the immune response to antigens?

  1. To neutralize toxins and pathogens

  2. To activate complement proteins

  3. To opsonize antigens for phagocytosis

  4. All of the above


Correct Option: D
Explanation:

Antibodies play a variety of roles in the immune response to antigens, including neutralizing toxins and pathogens, activating complement proteins, and opsonizing antigens for phagocytosis.

What is the difference between an antigen and an epitope?

  1. An antigen is the entire molecule that triggers an immune response, while an epitope is the specific part of the antigen that is recognized by antibodies or T cells

  2. An antigen is a foreign substance, while an epitope is a self-antigen

  3. An antigen is recognized by B cells, while an epitope is recognized by T cells

  4. An antigen is produced by the immune system, while an epitope is produced by the pathogen


Correct Option: A
Explanation:

An antigen is the entire molecule that triggers an immune response, while an epitope is the specific part of the antigen that is recognized by antibodies or T cells.

What is the role of MHC molecules in the immune response to antigens?

  1. To present antigens to T cells

  2. To activate B cells

  3. To produce antibodies

  4. To destroy infected cells


Correct Option: A
Explanation:

MHC molecules are cell surface proteins that present antigens to T cells, which are essential for the activation of the adaptive immune response.

What is the difference between humoral immunity and cell-mediated immunity?

  1. Humoral immunity is mediated by antibodies, while cell-mediated immunity is mediated by T cells

  2. Humoral immunity is effective against extracellular pathogens, while cell-mediated immunity is effective against intracellular pathogens

  3. Humoral immunity is short-lived, while cell-mediated immunity is long-lived

  4. All of the above


Correct Option: D
Explanation:

Humoral immunity is mediated by antibodies, while cell-mediated immunity is mediated by T cells. Humoral immunity is effective against extracellular pathogens, while cell-mediated immunity is effective against intracellular pathogens. Humoral immunity is short-lived, while cell-mediated immunity is long-lived.

What is the role of memory cells in the immune response to antigens?

  1. To provide long-term protection against infection

  2. To produce antibodies against antigens

  3. To activate T cells

  4. To destroy infected cells


Correct Option: A
Explanation:

Memory cells are long-lived cells that provide long-term protection against infection by rapidly responding to re-exposure to the same antigen.

What is the difference between active immunity and passive immunity?

  1. Active immunity is acquired through infection or vaccination, while passive immunity is acquired through the transfer of antibodies or T cells from another individual

  2. Active immunity is long-lived, while passive immunity is short-lived

  3. Active immunity is more effective against intracellular pathogens, while passive immunity is more effective against extracellular pathogens

  4. All of the above


Correct Option: D
Explanation:

Active immunity is acquired through infection or vaccination, while passive immunity is acquired through the transfer of antibodies or T cells from another individual. Active immunity is long-lived, while passive immunity is short-lived. Active immunity is more effective against intracellular pathogens, while passive immunity is more effective against extracellular pathogens.

What is the role of vaccines in the immune response to antigens?

  1. To stimulate the production of antibodies and T cells against a specific pathogen

  2. To provide long-term protection against infection

  3. To reduce the severity of disease

  4. All of the above


Correct Option: D
Explanation:

Vaccines stimulate the production of antibodies and T cells against a specific pathogen, providing long-term protection against infection and reducing the severity of disease.

What is the difference between a primary immune response and a secondary immune response?

  1. A primary immune response is the first time the immune system encounters an antigen, while a secondary immune response is a subsequent encounter with the same antigen

  2. A primary immune response is slower and weaker than a secondary immune response

  3. A primary immune response produces only IgM antibodies, while a secondary immune response produces both IgM and IgG antibodies

  4. All of the above


Correct Option: D
Explanation:

A primary immune response is the first time the immune system encounters an antigen, while a secondary immune response is a subsequent encounter with the same antigen. A primary immune response is slower and weaker than a secondary immune response. A primary immune response produces only IgM antibodies, while a secondary immune response produces both IgM and IgG antibodies.

What is the role of cytokines in the immune response to antigens?

  1. To activate and regulate immune cells

  2. To promote the differentiation of B cells into plasma cells

  3. To stimulate the production of antibodies

  4. All of the above


Correct Option: D
Explanation:

Cytokines are small proteins that activate and regulate immune cells, promote the differentiation of B cells into plasma cells, and stimulate the production of antibodies.

What is the difference between an immune complex and an immune precipitate?

  1. An immune complex is a soluble complex of antigen and antibody, while an immune precipitate is an insoluble complex of antigen and antibody

  2. An immune complex is formed in the fluid phase, while an immune precipitate is formed on a cell surface

  3. An immune complex is smaller than an immune precipitate

  4. All of the above


Correct Option: D
Explanation:

An immune complex is a soluble complex of antigen and antibody, while an immune precipitate is an insoluble complex of antigen and antibody. An immune complex is formed in the fluid phase, while an immune precipitate is formed on a cell surface. An immune complex is smaller than an immune precipitate.

What is the role of complement proteins in the immune response to antigens?

  1. To lyse infected cells

  2. To opsonize antigens for phagocytosis

  3. To activate the inflammatory response

  4. All of the above


Correct Option: D
Explanation:

Complement proteins lyse infected cells, opsonize antigens for phagocytosis, and activate the inflammatory response.

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