Lost in Space, which aired from 1965 to 1968, followed the adventures of the Robinson family as they traveled through space in their spaceship, the Jupiter 2.

Babylon 5, which aired from 1993 to 1998, was set on a massive space station called Babylon 5, which served as a diplomatic and commercial hub for various alien races.

The X-Files, which aired from 1993 to 2002, followed the investigations of FBI agents Fox Mulder and Dana Scully as they explored unexplained phenomena, including extraterrestrial encounters.

The Enterprise-D was the flagship of the United Federation of Planets in Star Trek: The Next Generation, which aired from 1987 to 1994.

Doctor Who, which has been airing since 1963, follows the adventures of the Doctor, a time-traveling alien who explores the universe in his TARDIS (Time And Relative Dimension In Space).

Quantum Leap, which aired from 1989 to 1993, featured Dr. Sam Beckett, a physicist who traveled through time by 'leaping' into the bodies of different people throughout history.

The Quantum Mirror was a device used by the characters in Sliders, which aired from 1995 to 2000, to travel between different parallel universes.

Stargate SG-1, which aired from 1997 to 2007, followed the adventures of a team of military personnel and scientists who traveled through a Stargate to explore other planets and galaxies.

Moya was a living spaceship in Farscape, which aired from 1999 to 2003, that served as the home and mode of transportation for the main characters.

Firefly, which aired in 2002, followed the adventures of the crew of the spaceship Serenity as they navigated the aftermath of a civil war and encountered various challenges and conflicts.

Galactica was the flagship of the Colonial Fleet in Battlestar Galactica, which aired from 2004 to 2009, and served as the home and base of operations for the surviving humans after a devastating attack by the Cylons.

The Expanse, which aired from 2015 to 2022, followed the adventures of the crew of the Rocinante as they navigated the complex political, social, and scientific challenges of a colonized solar system.

Dutch, Johnny, and D'avin were the space bounty hunter trio in Killjoys, which aired from 2015 to 2019, who traveled on a ship called 'Dutch' and encountered various adventures and challenges.

The Orville, which aired from 2017 to 2022, followed the adventures of the crew of the Orville, a mid-level exploratory spaceship, as they encountered various comedic and dramatic situations while exploring the universe.

Rick Sanchez was the mad scientist in Rick and Morty, which aired from 2013 to present, who traveled through space and time with his grandson, Morty Smith, encountering various bizarre and dangerous adventures.