The Coahuiltecan were the first Native American tribe to settle in the San Antonio River Valley, arriving around 10,000 years ago.

Mission San Antonio de Valero, also known as the Alamo, was the first Spanish mission established in the San Antonio River Valley.

The Battle of the Alamo was a famous battle during the Texas Revolution, where a small group of Texan defenders held out against a much larger Mexican army for 13 days.

Edward Dwyer was the first mayor of San Antonio, serving from 1837 to 1839.

The San Antonio River is the river that flows through the San Antonio River Valley.

San Antonio is located at the headwaters of the San Antonio River.

Olmos Dam was built on the San Antonio River in 1928.

The River Walk is a park located along the San Antonio River in downtown San Antonio.

The San Antonio River Festival is an annual festival that is held in San Antonio to celebrate the San Antonio River.

The University of Texas at San Antonio is located on the banks of the San Antonio River.

The King William Historic District is a historic district that is located along the San Antonio River in San Antonio.

The Witte Museum is located on the banks of the San Antonio River in San Antonio.

The Tobin Center for the Performing Arts is located on the banks of the San Antonio River in San Antonio.

The Houston Street Bridge crosses the San Antonio River in downtown San Antonio.

The San Antonio River Regatta is an annual boat race that is held on the San Antonio River.