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Immunology of Infectious Diseases

Description: Test your knowledge on the fundamentals of Immunology of Infectious Diseases.
Number of Questions: 15
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Tags: immunology infectious diseases pathogens immune response
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Which type of immune response is primarily responsible for defending against extracellular bacteria and toxins?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: B
Explanation:

Humoral immunity, mediated by antibodies, plays a crucial role in neutralizing extracellular bacteria and their toxins, preventing infection.

What type of immune cell is responsible for phagocytosing and destroying pathogens?

  1. Neutrophils

  2. Macrophages

  3. Dendritic cells

  4. B cells


Correct Option: A
Explanation:

Neutrophils, a type of phagocytic white blood cell, are the first responders to infection, engulfing and destroying pathogens through phagocytosis.

Which type of antibody is most effective in neutralizing viruses?

  1. IgA

  2. IgD

  3. IgG

  4. IgM


Correct Option: D
Explanation:

IgM antibodies are the first line of defense against viral infections, providing immediate, albeit short-lived, protection.

What is the role of memory cells in the immune response?

  1. Producing antibodies

  2. Engulfing pathogens

  3. Releasing cytokines

  4. Remembering past infections


Correct Option: D
Explanation:

Memory cells retain information about past infections, enabling a rapid and robust immune response upon re-exposure to the same pathogen.

Which cytokine is primarily responsible for coordinating the inflammatory response?

  1. Interferon-gamma

  2. Interleukin-2

  3. Tumor necrosis factor-alpha

  4. Interleukin-10


Correct Option: C
Explanation:

Tumor necrosis factor-alpha (TNF-alpha) is a key cytokine involved in initiating and regulating the inflammatory response.

What is the function of cytotoxic T cells in the immune response?

  1. Producing antibodies

  2. Releasing cytokines

  3. Engulfing pathogens

  4. Killing infected cells


Correct Option: D
Explanation:

Cytotoxic T cells, also known as killer T cells, are responsible for eliminating virus-infected cells and cancerous cells.

Which type of immune response is characterized by a delayed hypersensitivity reaction?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: A
Explanation:

Cell-mediated immunity, involving the activation of T cells and macrophages, is responsible for delayed hypersensitivity reactions, such as those seen in tuberculin skin tests.

What is the primary function of natural killer (NK) cells in the immune system?

  1. Producing antibodies

  2. Engulfing pathogens

  3. Killing infected cells

  4. Releasing cytokines


Correct Option: C
Explanation:

Natural killer (NK) cells are cytotoxic lymphocytes that play a crucial role in eliminating virus-infected cells and tumor cells.

Which type of immune response is responsible for protecting mucosal surfaces from infection?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: C
Explanation:

Innate immunity, including physical barriers, chemical mediators, and phagocytic cells, provides the first line of defense against pathogens at mucosal surfaces.

What is the role of interferons in the immune response?

  1. Producing antibodies

  2. Engulfing pathogens

  3. Killing infected cells

  4. Inhibiting viral replication


Correct Option: D
Explanation:

Interferons are cytokines that play a crucial role in inhibiting viral replication and activating immune cells.

Which type of immune response is responsible for generating memory cells?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: D
Explanation:

Adaptive immunity, involving the activation and differentiation of lymphocytes, is responsible for generating memory cells that provide long-term protection against pathogens.

What is the function of dendritic cells in the immune system?

  1. Producing antibodies

  2. Engulfing pathogens

  3. Killing infected cells

  4. Presenting antigens to immune cells


Correct Option: D
Explanation:

Dendritic cells are specialized antigen-presenting cells that capture, process, and present antigens to T cells, initiating the adaptive immune response.

Which type of immune response is primarily responsible for defending against intracellular bacteria and viruses?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: A
Explanation:

Cell-mediated immunity, involving the activation of T cells and macrophages, plays a crucial role in defending against intracellular pathogens.

What is the role of complement proteins in the immune response?

  1. Producing antibodies

  2. Engulfing pathogens

  3. Killing infected cells

  4. Activating the inflammatory response


Correct Option: D
Explanation:

Complement proteins are a group of proteins that work together to activate the inflammatory response, enhance phagocytosis, and directly kill pathogens.

Which type of immune response is responsible for providing long-term protection against pathogens?

  1. Cell-mediated immunity

  2. Humoral immunity

  3. Innate immunity

  4. Adaptive immunity


Correct Option: D
Explanation:

Adaptive immunity, involving the activation and differentiation of lymphocytes, provides long-term protection against pathogens through the generation of memory cells.

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