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Translation: The Conversion of RNA into Protein

Description: Test your understanding of the process of translation, where the genetic information encoded in mRNA is converted into a protein.
Number of Questions: 15
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Tags: translation protein synthesis genetic code ribosomes trna
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What is the primary function of tRNA in the process of translation?

  1. To carry amino acids to the ribosome

  2. To decode the genetic information in mRNA

  3. To form peptide bonds between amino acids

  4. To release the newly synthesized protein from the ribosome


Correct Option: A
Explanation:

tRNA molecules are responsible for bringing specific amino acids to the ribosome, based on the sequence of codons in the mRNA.

What is the role of the ribosome in translation?

  1. To assemble amino acids into a polypeptide chain

  2. To proofread the sequence of amino acids in the protein

  3. To release the newly synthesized protein from the tRNA

  4. To transport mRNA from the nucleus to the cytoplasm


Correct Option: A
Explanation:

The ribosome is a complex structure that catalyzes the formation of peptide bonds between amino acids, resulting in the assembly of a polypeptide chain.

What is the sequence of events that occurs during translation?

  1. Initiation, Elongation, Termination

  2. Transcription, Translation, Replication

  3. Glycolysis, Krebs Cycle, Electron Transport Chain

  4. Mitosis, Meiosis, Fertilization


Correct Option: A
Explanation:

Translation involves three main stages: initiation, elongation, and termination. During initiation, the ribosome binds to the mRNA and the start codon. Elongation involves the sequential addition of amino acids to the growing polypeptide chain. Termination occurs when a stop codon is encountered, signaling the release of the newly synthesized protein.

Which of the following is NOT a stop codon?

  1. UAA

  2. UAG

  3. UGA

  4. AUG


Correct Option: D
Explanation:

UAA, UAG, and UGA are the three stop codons in the genetic code. AUG, on the other hand, is the start codon, which signals the beginning of protein synthesis.

How many tRNA molecules are required to decode all 64 codons in the genetic code?

  1. 20

  2. 32

  3. 48

  4. 64


Correct Option: C
Explanation:

There are 64 codons in the genetic code, but only 20 amino acids. This means that some amino acids are encoded by multiple codons. As a result, 48 tRNA molecules are required to decode all 64 codons.

What is the role of release factors in translation?

  1. To bind to the ribosome and release the newly synthesized protein

  2. To proofread the sequence of amino acids in the protein

  3. To recruit tRNA molecules to the ribosome

  4. To terminate transcription of the mRNA


Correct Option: A
Explanation:

Release factors bind to the ribosome when a stop codon is encountered in the mRNA. This binding causes the ribosome to release the newly synthesized protein and terminate translation.

Which of the following is NOT a component of the translation initiation complex?

  1. mRNA

  2. tRNA

  3. Ribosome

  4. Initiation factors


Correct Option: B
Explanation:

The translation initiation complex consists of mRNA, the ribosome, and initiation factors. tRNA molecules are not involved in the initiation complex, but they are required for the elongation stage of translation.

What is the role of elongation factors in translation?

  1. To recruit tRNA molecules to the ribosome

  2. To catalyze the formation of peptide bonds between amino acids

  3. To proofread the sequence of amino acids in the protein

  4. To release the newly synthesized protein from the ribosome


Correct Option: A
Explanation:

Elongation factors are responsible for recruiting tRNA molecules to the ribosome, based on the sequence of codons in the mRNA. They also help in the movement of the ribosome along the mRNA.

What is the sequence of events that occurs during the elongation stage of translation?

  1. Binding of tRNA to the ribosome, Peptide bond formation, Translocation

  2. Initiation, Elongation, Termination

  3. Transcription, Translation, Replication

  4. Glycolysis, Krebs Cycle, Electron Transport Chain


Correct Option: A
Explanation:

The elongation stage of translation involves the sequential addition of amino acids to the growing polypeptide chain. This process consists of three main steps: binding of tRNA to the ribosome, formation of a peptide bond between the amino acids, and translocation of the ribosome along the mRNA.

What is the role of GTP in translation?

  1. To provide energy for the movement of the ribosome along the mRNA

  2. To catalyze the formation of peptide bonds between amino acids

  3. To proofread the sequence of amino acids in the protein

  4. To release the newly synthesized protein from the ribosome


Correct Option: A
Explanation:

GTP is a molecule that provides energy for various cellular processes. In translation, GTP is used to power the movement of the ribosome along the mRNA during the elongation stage.

What is the role of the Shine-Dalgarno sequence in translation?

  1. To recruit the ribosome to the start codon of the mRNA

  2. To proofread the sequence of amino acids in the protein

  3. To release the newly synthesized protein from the ribosome

  4. To terminate transcription of the mRNA


Correct Option: A
Explanation:

The Shine-Dalgarno sequence is a short sequence of nucleotides located upstream of the start codon in prokaryotic mRNAs. It helps in recruiting the ribosome to the start codon and initiating translation.

Which of the following is NOT a type of RNA molecule involved in translation?

  1. mRNA

  2. tRNA

  3. rRNA

  4. snRNA


Correct Option: D
Explanation:

mRNA, tRNA, and rRNA are the three main types of RNA molecules involved in translation. snRNA is involved in a different cellular process called splicing, which occurs during the processing of pre-mRNA.

What is the role of the Kozak sequence in translation?

  1. To recruit the ribosome to the start codon of the mRNA

  2. To proofread the sequence of amino acids in the protein

  3. To release the newly synthesized protein from the ribosome

  4. To terminate transcription of the mRNA


Correct Option: A
Explanation:

The Kozak sequence is a short sequence of nucleotides located around the start codon in eukaryotic mRNAs. It helps in recruiting the ribosome to the start codon and initiating translation.

Which of the following is NOT a modification that can occur to tRNA molecules?

  1. Methylation

  2. Pseudouridylation

  3. Phosphorylation

  4. Deamination


Correct Option: C
Explanation:

Methylation, pseudouridylation, and deamination are common modifications that occur to tRNA molecules. Phosphorylation, on the other hand, is not a typical modification for tRNA.

What is the role of the peptidyl transferase center in translation?

  1. To catalyze the formation of peptide bonds between amino acids

  2. To proofread the sequence of amino acids in the protein

  3. To release the newly synthesized protein from the ribosome

  4. To terminate transcription of the mRNA


Correct Option: A
Explanation:

The peptidyl transferase center is a component of the ribosome that catalyzes the formation of peptide bonds between amino acids during the elongation stage of translation.

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