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Biophysics of Infectious Diseases

Description: Biophysics of Infectious Diseases
Number of Questions: 15
Created by:
Tags: biophysics infectious diseases pathogenesis host-pathogen interactions
Attempted 0/15 Correct 0 Score 0

What is the primary mechanism by which viruses enter host cells?

  1. Endocytosis

  2. Phagocytosis

  3. Pinocytosis

  4. Direct penetration


Correct Option: D
Explanation:

Viruses typically enter host cells through direct penetration of the cell membrane, using specialized proteins or glycoproteins on their surface.

Which type of immune response is primarily responsible for recognizing and eliminating virus-infected cells?

  1. Humoral immune response

  2. Cell-mediated immune response

  3. Innate immune response

  4. Adaptive immune response


Correct Option: B
Explanation:

The cell-mediated immune response, particularly cytotoxic T cells, plays a crucial role in recognizing and eliminating virus-infected cells by directly targeting and destroying them.

What is the term used to describe the ability of a pathogen to evade or suppress the host's immune response?

  1. Immunosuppression

  2. Immunoevasion

  3. Immunodeficiency

  4. Immune tolerance


Correct Option: B
Explanation:

Immunoevasion refers to the strategies employed by pathogens to escape or counteract the host's immune defenses, allowing them to persist and cause infection.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial cell walls?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Aminoglycosides


Correct Option: A
Explanation:

Beta-lactam antibiotics, such as penicillin and cephalosporins, are a class of antimicrobial agents that specifically target and inhibit the synthesis of bacterial cell walls, leading to cell death.

What is the primary mechanism by which bacteria cause disease in humans?

  1. Direct cell damage

  2. Toxins

  3. Immune system activation

  4. Nutrient depletion


Correct Option: B
Explanation:

Bacteria often cause disease by producing toxins, which are harmful substances that can damage host cells and tissues, leading to various symptoms and complications.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial proteins?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Aminoglycosides


Correct Option: B
Explanation:

Tetracyclines are a class of antimicrobial agents that primarily target and inhibit the synthesis of bacterial proteins, interfering with their growth and replication.

What is the term used to describe the ability of a pathogen to survive and multiply within host cells?

  1. Pathogenicity

  2. Virulence

  3. Infectivity

  4. Transmissibility


Correct Option: A
Explanation:

Pathogenicity refers to the ability of a pathogen to cause disease in a host organism, including its capacity to survive, multiply, and damage host tissues.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial DNA?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Fluoroquinolones


Correct Option: D
Explanation:

Fluoroquinolones are a class of antimicrobial agents that primarily target and inhibit the synthesis of bacterial DNA, interfering with their replication and causing cell death.

What is the term used to describe the ability of a pathogen to be transmitted from one host to another?

  1. Pathogenicity

  2. Virulence

  3. Infectivity

  4. Transmissibility


Correct Option: D
Explanation:

Transmissibility refers to the ability of a pathogen to be transferred from an infected host to a susceptible host, either through direct contact, indirect contact, or via vectors.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial RNA?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Rifamycins


Correct Option: D
Explanation:

Rifamycins are a class of antimicrobial agents that primarily target and inhibit the synthesis of bacterial RNA, interfering with their transcription and protein synthesis.

What is the term used to describe the ability of a pathogen to cause severe disease or death in a host organism?

  1. Pathogenicity

  2. Virulence

  3. Infectivity

  4. Transmissibility


Correct Option: B
Explanation:

Virulence refers to the degree of pathogenicity of a microorganism, indicating its ability to cause severe disease or death in a host organism.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial cell membranes?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Polymyxins


Correct Option: D
Explanation:

Polymyxins are a class of antimicrobial agents that primarily target and disrupt the synthesis of bacterial cell membranes, leading to leakage of cell contents and cell death.

What is the term used to describe the ability of a pathogen to establish and maintain an infection in a host organism?

  1. Pathogenicity

  2. Virulence

  3. Infectivity

  4. Persistence


Correct Option: D
Explanation:

Persistence refers to the ability of a pathogen to survive and remain viable within a host organism, often evading the host's immune defenses and causing chronic or recurrent infections.

Which type of antimicrobial agent targets and inhibits the synthesis of bacterial folic acid?

  1. Beta-lactam antibiotics

  2. Tetracyclines

  3. Macrolides

  4. Sulfonamides


Correct Option: D
Explanation:

Sulfonamides are a class of antimicrobial agents that primarily target and inhibit the synthesis of bacterial folic acid, an essential cofactor for various metabolic processes.

What is the term used to describe the ability of a pathogen to cause infection in a host organism?

  1. Pathogenicity

  2. Virulence

  3. Infectivity

  4. Transmissibility


Correct Option: C
Explanation:

Infectivity refers to the ability of a pathogen to enter and establish an infection in a host organism, often quantified by the number of organisms required to cause infection.

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