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Cell-Mediated Immunity and T Cells

Description: This quiz assesses your understanding of cell-mediated immunity and the role of T cells in the immune response.
Number of Questions: 15
Created by:
Tags: cell-mediated immunity t cells adaptive immunity
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Which type of immune response is primarily responsible for combating intracellular pathogens and cancer cells?

  1. Humoral immunity

  2. Cell-mediated immunity

  3. Innate immunity

  4. Passive immunity


Correct Option: B
Explanation:

Cell-mediated immunity is a type of adaptive immune response that involves the activation of T cells to directly target and destroy infected cells or cancer cells.

What are the two main types of T cells involved in cell-mediated immunity?

  1. Helper T cells and cytotoxic T cells

  2. Regulatory T cells and memory T cells

  3. Natural killer T cells and gamma delta T cells

  4. Th1 cells and Th2 cells


Correct Option: A
Explanation:

Helper T cells activate other immune cells and cytotoxic T cells directly kill infected or cancerous cells.

What is the function of helper T cells in cell-mediated immunity?

  1. They directly kill infected or cancerous cells.

  2. They activate cytotoxic T cells and B cells.

  3. They produce antibodies to neutralize pathogens.

  4. They suppress the immune response to prevent excessive inflammation.


Correct Option: B
Explanation:

Helper T cells secrete cytokines that activate cytotoxic T cells and B cells, which then carry out the immune response.

What is the function of cytotoxic T cells in cell-mediated immunity?

  1. They activate helper T cells and B cells.

  2. They directly kill infected or cancerous cells.

  3. They produce antibodies to neutralize pathogens.

  4. They suppress the immune response to prevent excessive inflammation.


Correct Option: B
Explanation:

Cytotoxic T cells release cytotoxic molecules that directly kill infected or cancerous cells.

Which molecule is recognized by T cells to initiate an immune response?

  1. Antibodies

  2. Antigens

  3. Cytokines

  4. Complement proteins


Correct Option: B
Explanation:

T cells recognize antigens presented on the surface of antigen-presenting cells (APCs) via major histocompatibility complex (MHC) molecules.

What is the role of MHC molecules in cell-mediated immunity?

  1. They present antigens to T cells.

  2. They activate cytotoxic T cells.

  3. They produce antibodies to neutralize pathogens.

  4. They suppress the immune response to prevent excessive inflammation.


Correct Option: A
Explanation:

MHC molecules bind to antigens and present them on the surface of APCs, allowing T cells to recognize and respond to the antigens.

Which type of MHC molecule is responsible for presenting antigens to CD8+ cytotoxic T cells?

  1. MHC class I

  2. MHC class II

  3. MHC class III

  4. MHC class IV


Correct Option: A
Explanation:

MHC class I molecules present antigens to CD8+ cytotoxic T cells, which are responsible for killing infected or cancerous cells.

Which type of MHC molecule is responsible for presenting antigens to CD4+ helper T cells?

  1. MHC class I

  2. MHC class II

  3. MHC class III

  4. MHC class IV


Correct Option: B
Explanation:

MHC class II molecules present antigens to CD4+ helper T cells, which activate other immune cells and help B cells produce antibodies.

What is the role of memory T cells in cell-mediated immunity?

  1. They directly kill infected or cancerous cells.

  2. They activate cytotoxic T cells and B cells.

  3. They provide long-term immunity by responding quickly to reinfection.

  4. They suppress the immune response to prevent excessive inflammation.


Correct Option: C
Explanation:

Memory T cells remain in the body after an infection and can quickly respond to the same pathogen if it is encountered again, providing long-term immunity.

What is the difference between cell-mediated immunity and humoral immunity?

  1. Cell-mediated immunity involves T cells, while humoral immunity involves B cells.

  2. Cell-mediated immunity targets intracellular pathogens, while humoral immunity targets extracellular pathogens.

  3. Cell-mediated immunity provides long-term immunity, while humoral immunity provides short-term immunity.

  4. All of the above.


Correct Option: D
Explanation:

Cell-mediated immunity involves T cells and targets intracellular pathogens, while humoral immunity involves B cells and targets extracellular pathogens. Cell-mediated immunity also provides long-term immunity through memory T cells.

Which cytokine is produced by helper T cells to activate cytotoxic T cells?

  1. Interleukin-2 (IL-2)

  2. Interleukin-4 (IL-4)

  3. Interleukin-10 (IL-10)

  4. Interferon-gamma (IFN-γ)


Correct Option: A
Explanation:

Interleukin-2 (IL-2) is a cytokine produced by helper T cells that activates cytotoxic T cells and promotes their proliferation.

What is the role of natural killer (NK) cells in cell-mediated immunity?

  1. They directly kill infected or cancerous cells.

  2. They activate cytotoxic T cells and B cells.

  3. They produce antibodies to neutralize pathogens.

  4. They suppress the immune response to prevent excessive inflammation.


Correct Option: A
Explanation:

Natural killer (NK) cells are a type of innate immune cell that can directly kill infected or cancerous cells without prior sensitization.

Which molecule is expressed on the surface of cytotoxic T cells and is responsible for killing target cells?

  1. CD4

  2. CD8

  3. TCR

  4. MHC


Correct Option: B
Explanation:

CD8 is a molecule expressed on the surface of cytotoxic T cells that binds to MHC class I molecules on target cells, allowing the cytotoxic T cell to kill the target cell.

What is the role of regulatory T cells (Tregs) in cell-mediated immunity?

  1. They directly kill infected or cancerous cells.

  2. They activate cytotoxic T cells and B cells.

  3. They suppress the immune response to prevent excessive inflammation.

  4. They produce antibodies to neutralize pathogens.


Correct Option: C
Explanation:

Regulatory T cells (Tregs) are a type of T cell that suppresses the immune response to prevent excessive inflammation and autoimmune reactions.

Which cytokine is produced by helper T cells to activate macrophages and promote phagocytosis?

  1. Interleukin-2 (IL-2)

  2. Interleukin-4 (IL-4)

  3. Interleukin-10 (IL-10)

  4. Interferon-gamma (IFN-γ)


Correct Option: D
Explanation:

Interferon-gamma (IFN-γ) is a cytokine produced by helper T cells that activates macrophages and promotes phagocytosis, helping to clear intracellular pathogens.

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