Drug Storage and Stability

Description: This quiz covers the important aspects of drug storage and stability, including factors affecting drug stability, proper storage conditions, and methods for maintaining drug integrity.
Number of Questions: 15
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Tags: pharmaceuticals drug storage drug stability medication management
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Which of the following factors can significantly impact the stability of a drug?

  1. Temperature

  2. Light

  3. Humidity

  4. pH

  5. All of the above


Correct Option: E
Explanation:

Drug stability can be affected by various factors, including temperature, light, humidity, pH, and the presence of other chemicals.

What is the recommended storage temperature range for most drugs?

  1. 15-25°C (59-77°F)

  2. 2-8°C (36-46°F)

  3. 25-30°C (77-86°F)

  4. 10-15°C (50-59°F)

  5. 30-35°C (86-95°F)


Correct Option: A
Explanation:

The optimal storage temperature range for most drugs is typically between 15-25°C (59-77°F).

Which type of drug requires refrigeration (2-8°C) for storage?

  1. Antibiotics

  2. Vaccines

  3. Insulin

  4. All of the above

  5. None of the above


Correct Option: D
Explanation:

Antibiotics, vaccines, and insulin are examples of drugs that require refrigeration to maintain their stability and effectiveness.

What is the primary purpose of using light-resistant containers for drug storage?

  1. To prevent photodegradation

  2. To maintain sterility

  3. To prevent moisture ingress

  4. To enhance drug absorption

  5. To improve drug stability


Correct Option: A
Explanation:

Light-resistant containers are used to protect drugs from photodegradation, which is the breakdown of drugs due to exposure to light.

Which of the following storage conditions is ideal for maintaining the stability of nitroglycerin tablets?

  1. Cool and dry place

  2. Refrigerator

  3. Room temperature

  4. Direct sunlight

  5. High humidity environment


Correct Option: A
Explanation:

Nitroglycerin tablets should be stored in a cool and dry place to prevent decomposition and maintain their potency.

What is the recommended storage condition for suppositories?

  1. Refrigerator

  2. Room temperature

  3. Freezer

  4. Direct sunlight

  5. High humidity environment


Correct Option: A
Explanation:

Suppositories are typically stored in a refrigerator to maintain their shape and prevent melting.

Which of the following drugs should be stored in a tightly sealed container?

  1. Aspirin

  2. Ibuprofen

  3. Acetaminophen

  4. All of the above

  5. None of the above


Correct Option: D
Explanation:

Aspirin, ibuprofen, and acetaminophen are all drugs that should be stored in tightly sealed containers to prevent moisture absorption and maintain their stability.

What is the primary reason for conducting stability studies on drugs?

  1. To determine drug efficacy

  2. To assess drug safety

  3. To evaluate drug stability under various conditions

  4. To determine drug interactions

  5. To establish drug dosage


Correct Option: C
Explanation:

Stability studies are conducted to evaluate how a drug's physical, chemical, and biological properties change over time under various storage conditions.

Which of the following is a common method for assessing drug stability?

  1. Accelerated stability testing

  2. Real-time stability testing

  3. In vitro stability testing

  4. In vivo stability testing

  5. All of the above


Correct Option: E
Explanation:

Accelerated stability testing, real-time stability testing, in vitro stability testing, and in vivo stability testing are all common methods used to assess drug stability.

What is the purpose of conducting accelerated stability studies?

  1. To predict long-term stability

  2. To evaluate drug efficacy

  3. To assess drug safety

  4. To determine drug interactions

  5. To establish drug dosage


Correct Option: A
Explanation:

Accelerated stability studies are conducted to predict the long-term stability of a drug under exaggerated storage conditions.

Which of the following factors is NOT considered when establishing storage conditions for drugs?

  1. Drug stability data

  2. Patient compliance

  3. Drug formulation

  4. Regulatory requirements

  5. Cost of storage


Correct Option: E
Explanation:

While drug stability data, patient compliance, drug formulation, and regulatory requirements are all considered when establishing storage conditions, cost of storage is generally not a primary factor.

What is the recommended storage condition for controlled substances?

  1. Locked cabinet

  2. Refrigerator

  3. Room temperature

  4. Direct sunlight

  5. High humidity environment


Correct Option: A
Explanation:

Controlled substances should be stored in a locked cabinet to prevent unauthorized access and theft.

Which of the following is NOT a good practice for maintaining drug stability?

  1. Storing drugs in their original containers

  2. Exposing drugs to direct sunlight

  3. Storing drugs in a cool and dry place

  4. Using drugs beyond their expiration date

  5. Inspecting drugs for physical changes before use


Correct Option: B
Explanation:

Exposing drugs to direct sunlight can degrade their active ingredients and reduce their effectiveness.

What is the primary role of a pharmacist in ensuring drug stability?

  1. Educating patients about proper drug storage

  2. Monitoring drug expiration dates

  3. Conducting stability studies

  4. Developing drug formulations

  5. All of the above


Correct Option: E
Explanation:

Pharmacists play a crucial role in ensuring drug stability by educating patients about proper drug storage, monitoring drug expiration dates, conducting stability studies, and developing drug formulations.

Which of the following is NOT a common type of stability study conducted on drugs?

  1. Accelerated stability testing

  2. Real-time stability testing

  3. In vitro stability testing

  4. In vivo stability testing

  5. Photostability testing


Correct Option: D
Explanation:

In vivo stability testing is not a common type of stability study conducted on drugs, as it involves testing drug stability within a living organism.

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