Immunotherapy

Description: Immunotherapy Quiz: Test Your Knowledge on Harnessing the Immune System to Fight Diseases
Number of Questions: 15
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Tags: immunotherapy immune system cancer treatment immunology
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What is the primary goal of immunotherapy?

  1. To suppress the immune system

  2. To enhance the immune system's ability to fight diseases

  3. To replace damaged immune cells

  4. To introduce foreign antigens into the body


Correct Option: B
Explanation:

Immunotherapy aims to harness the body's immune system to recognize and eliminate diseased cells, primarily cancer cells, by boosting its natural defenses.

Which type of immunotherapy involves the use of immune checkpoint inhibitors?

  1. Adoptive cell therapy

  2. Cancer vaccines

  3. Immune checkpoint blockade

  4. Cytokine therapy


Correct Option: C
Explanation:

Immune checkpoint blockade involves the use of antibodies that block inhibitory immune checkpoints, such as PD-1 and CTLA-4, to unleash the anti-tumor activity of T cells.

What is the mechanism of action of adoptive cell therapy?

  1. Stimulating the production of antibodies

  2. Introducing tumor-specific antigens into the body

  3. Engineering immune cells to recognize and attack cancer cells

  4. Blocking the activity of immunosuppressive cells


Correct Option: C
Explanation:

Adoptive cell therapy involves modifying and expanding a patient's own immune cells, such as T cells, to recognize and attack cancer cells more effectively.

Which type of immunotherapy utilizes genetically engineered T cells to target cancer cells?

  1. Immune checkpoint blockade

  2. Cytokine therapy

  3. Cancer vaccines

  4. Chimeric antigen receptor (CAR) T-cell therapy


Correct Option: D
Explanation:

CAR T-cell therapy involves genetically modifying T cells to express chimeric antigen receptors (CARs) that recognize and bind to specific antigens on cancer cells, leading to their destruction.

What is the primary function of immune checkpoint inhibitors in immunotherapy?

  1. Activating T cells

  2. Suppressing the immune response

  3. Blocking the activity of immunosuppressive cells

  4. Producing antibodies against cancer cells


Correct Option: C
Explanation:

Immune checkpoint inhibitors work by blocking the activity of inhibitory immune checkpoints, such as PD-1 and CTLA-4, which normally suppress T cell activity, thereby enhancing the anti-tumor immune response.

Which type of immunotherapy involves the use of cytokines to stimulate the immune system?

  1. Adoptive cell therapy

  2. Immune checkpoint blockade

  3. Cytokine therapy

  4. Cancer vaccines


Correct Option: C
Explanation:

Cytokine therapy involves administering cytokines, such as interleukin-2 (IL-2) and interferon-alpha (IFN-α), to stimulate and enhance the immune system's response against cancer cells.

What is the mechanism of action of cancer vaccines in immunotherapy?

  1. Blocking the activity of immunosuppressive cells

  2. Introducing tumor-specific antigens into the body

  3. Engineering immune cells to recognize and attack cancer cells

  4. Stimulating the production of antibodies


Correct Option: B
Explanation:

Cancer vaccines work by introducing tumor-specific antigens into the body, which stimulates the immune system to recognize and mount an immune response against cancer cells.

Which type of immunotherapy involves the use of antibodies to target cancer cells?

  1. Immune checkpoint blockade

  2. Cytokine therapy

  3. Antibody-drug conjugates (ADCs)

  4. Cancer vaccines


Correct Option: C
Explanation:

Antibody-drug conjugates (ADCs) are composed of antibodies that are linked to cytotoxic drugs. When the antibody binds to a specific antigen on a cancer cell, it delivers the drug directly to the cancer cell, leading to its destruction.

What is the primary advantage of adoptive cell therapy over traditional chemotherapy?

  1. Reduced side effects

  2. Long-lasting immune memory

  3. Broad-spectrum activity against different cancer types

  4. Lower cost of treatment


Correct Option: B
Explanation:

Adoptive cell therapy offers the advantage of long-lasting immune memory, meaning that the modified immune cells can continue to recognize and attack cancer cells even after treatment is completed.

Which type of immunotherapy is commonly used to treat hematologic malignancies such as leukemia and lymphoma?

  1. Immune checkpoint blockade

  2. Cytokine therapy

  3. Adoptive cell therapy

  4. Cancer vaccines


Correct Option: C
Explanation:

Adoptive cell therapy, particularly CAR T-cell therapy, has shown promising results in treating hematologic malignancies by genetically modifying a patient's own T cells to target and eliminate cancer cells.

What is the primary mechanism of action of immune checkpoint blockade in cancer immunotherapy?

  1. Stimulating the production of antibodies

  2. Blocking the activity of immunosuppressive cells

  3. Introducing tumor-specific antigens into the body

  4. Engineering immune cells to recognize and attack cancer cells


Correct Option: B
Explanation:

Immune checkpoint blockade works by blocking the activity of inhibitory immune checkpoints, such as PD-1 and CTLA-4, which normally suppress T cell activity, thereby releasing the brakes on the immune system and allowing it to attack cancer cells more effectively.

Which type of immunotherapy involves the use of genetically modified viruses to infect and kill cancer cells?

  1. Immune checkpoint blockade

  2. Cytokine therapy

  3. Virotherapy

  4. Cancer vaccines


Correct Option: C
Explanation:

Virotherapy involves the use of genetically modified viruses that are engineered to selectively infect and kill cancer cells, while sparing healthy cells.

What is the primary goal of cancer vaccines in immunotherapy?

  1. To suppress the immune system

  2. To enhance the immune system's ability to fight cancer

  3. To replace damaged immune cells

  4. To introduce foreign antigens into the body


Correct Option: B
Explanation:

Cancer vaccines aim to stimulate the immune system to recognize and attack cancer cells by introducing tumor-specific antigens into the body, thereby generating an immune response against the cancer.

Which type of immunotherapy involves the use of antibodies to block the activity of immunosuppressive cells?

  1. Immune checkpoint blockade

  2. Cytokine therapy

  3. Antibody-drug conjugates (ADCs)

  4. Cancer vaccines


Correct Option: A
Explanation:

Immune checkpoint blockade involves the use of antibodies that target and block the activity of inhibitory immune checkpoints, such as PD-1 and CTLA-4, which normally suppress T cell activity, thereby enhancing the immune response against cancer cells.

What is the primary advantage of immune checkpoint blockade over traditional chemotherapy?

  1. Reduced side effects

  2. Long-lasting immune memory

  3. Broad-spectrum activity against different cancer types

  4. Lower cost of treatment


Correct Option: A
Explanation:

Immune checkpoint blockade often has reduced side effects compared to traditional chemotherapy, as it targets specific immune pathways rather than affecting healthy cells throughout the body.

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