Nina Sayers, played by Natalie Portman, exhibits symptoms of Obsessive-Compulsive Disorder (OCD) in the film 'Black Swan'. She has intrusive thoughts, engages in repetitive behaviors, and experiences anxiety when her rituals are disrupted.

In 'The Aviator', Leonardo DiCaprio portrays Howard Hughes, a wealthy industrialist and aviator who struggles with Obsessive-Compulsive Disorder (OCD). He exhibits excessive handwashing, counting rituals, and a fear of germs.

Pat Solitano, played by Bradley Cooper, is diagnosed with Bipolar Disorder in 'Silver Linings Playbook'. He experiences extreme mood swings, ranging from manic episodes to depressive episodes, which impact his relationships and daily life.

In 'Rain Man', Dustin Hoffman portrays Raymond Babbitt, a character with Autism Spectrum Disorder (ASD). The film highlights the challenges and strengths associated with ASD, including Raymond's savant abilities and his difficulty with social interactions.

Jack Torrance, played by Jack Nicholson, exhibits traits of Antisocial Personality Disorder in 'The Shining'. He shows a lack of empathy, disregard for social norms, and a tendency to engage in impulsive and aggressive behaviors.

Tiffany Maxwell, portrayed by Jennifer Lawrence, struggles with Borderline Personality Disorder (BPD) in 'Silver Linings Playbook'. She experiences intense emotions, unstable relationships, and impulsive behaviors, which impact her life and relationships.

Edward Norton's character in 'Fight Club' exhibits symptoms of Dissociative Identity Disorder (DID), formerly known as Multiple Personality Disorder. He has two distinct identities, one being Tyler Durden, and struggles with memory loss and a fragmented sense of self.

In 'The Machinist', Christian Bale's character Trevor Reznik suffers from severe insomnia. The film explores the psychological and physical toll of prolonged sleep deprivation, leading to hallucinations, paranoia, and a distorted sense of reality.

Lisbeth Salander, played by Rooney Mara, exhibits traits of Antisocial Personality Disorder in 'The Girl with the Dragon Tattoo'. She shows a lack of empathy, disregard for social norms, and a tendency to engage in impulsive and aggressive behaviors.

In 'Memento', Guy Pearce's character Leonard Shelby suffers from anterograde amnesia, a condition where he cannot form new memories. The film explores the challenges of living with this disorder and the impact it has on his life and relationships.

John Nash, portrayed by Russell Crowe, is diagnosed with schizophrenia in 'A Beautiful Mind'. The film follows his struggles with the disorder, including hallucinations, delusions, and disorganized thinking, as well as his journey towards recovery and management of his condition.

In 'The Joker', Joaquin Phoenix's character Arthur Fleck struggles with schizophrenia. The film explores the psychological and social factors that contribute to his transformation into the Joker, highlighting the challenges of living with a severe mental illness.

Malcolm Crowe, played by Bruce Willis, is diagnosed with Dissociative Identity Disorder in 'The Sixth Sense'. The film follows his journey as he comes to terms with his multiple personalities and the impact they have on his life and relationships.

In 'Shutter Island', Leonardo DiCaprio's character Teddy Daniels struggles with Post-Traumatic Stress Disorder (PTSD) as a result of his experiences during World War II. The film explores the psychological and emotional toll of trauma and the challenges of recovery.

Randle McMurphy, played by Jack Nicholson, exhibits traits of Antisocial Personality Disorder in 'One Flew Over the Cuckoo's Nest'. He shows a lack of empathy, disregard for social norms, and a tendency to engage in impulsive and aggressive behaviors.