B Cell Receptors

Description: B Cell Receptors Quiz
Number of Questions: 15
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Tags: immunology b cells antibodies
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What is the primary function of B cell receptors (BCRs)?

  1. To recognize and bind to specific antigens

  2. To produce antibodies

  3. To activate T cells

  4. To regulate the immune response


Correct Option: A
Explanation:

BCRs are expressed on the surface of B cells and are responsible for recognizing and binding to specific antigens. This binding event initiates the activation of B cells and the production of antibodies.

What is the structure of a BCR?

  1. A single immunoglobulin molecule

  2. A complex of immunoglobulin molecules and other proteins

  3. A transmembrane protein

  4. A cytoplasmic protein


Correct Option: B
Explanation:

BCRs are composed of a membrane-bound immunoglobulin molecule, called the antigen-binding fragment (Fab), and a transmembrane protein, called the Fc fragment. The Fab fragment is responsible for binding to antigens, while the Fc fragment is responsible for signaling to the B cell.

How many different types of BCRs can a single B cell express?

  1. One

  2. Two

  3. Several

  4. Hundreds


Correct Option: C
Explanation:

A single B cell can express several different types of BCRs, each with a different specificity for antigen. This allows B cells to recognize a wide range of different antigens.

What happens when a BCR binds to an antigen?

  1. The B cell is activated

  2. The B cell produces antibodies

  3. The B cell differentiates into a memory B cell

  4. The B cell dies


Correct Option: A
Explanation:

When a BCR binds to an antigen, the B cell is activated. This activation process leads to the production of antibodies and the differentiation of B cells into memory B cells.

What is the role of memory B cells?

  1. To provide long-term immunity to pathogens

  2. To produce antibodies quickly upon re-exposure to an antigen

  3. To help T cells activate other immune cells

  4. To regulate the immune response


Correct Option: A
Explanation:

Memory B cells are long-lived B cells that are generated during an immune response. These cells are responsible for providing long-term immunity to pathogens by quickly producing antibodies upon re-exposure to the same antigen.

What is the difference between a BCR and an antibody?

  1. BCRs are expressed on the surface of B cells, while antibodies are secreted by B cells

  2. BCRs are specific for a single antigen, while antibodies can recognize multiple antigens

  3. BCRs are composed of immunoglobulin molecules, while antibodies are composed of different types of proteins

  4. BCRs are involved in the activation of B cells, while antibodies are involved in the effector phase of the immune response


Correct Option: A
Explanation:

BCRs are expressed on the surface of B cells and are responsible for recognizing and binding to antigens. Antibodies are secreted by B cells and are responsible for neutralizing pathogens and activating other immune cells.

What is the role of B cells in the adaptive immune response?

  1. To produce antibodies

  2. To activate T cells

  3. To help T cells differentiate into memory T cells

  4. All of the above


Correct Option: D
Explanation:

B cells play a critical role in the adaptive immune response by producing antibodies, activating T cells, and helping T cells differentiate into memory T cells.

What is the role of B cells in the innate immune response?

  1. To produce antibodies

  2. To activate T cells

  3. To help T cells differentiate into memory T cells

  4. None of the above


Correct Option: D
Explanation:

B cells are not involved in the innate immune response.

What is the role of B cells in autoimmune diseases?

  1. To produce antibodies against self-antigens

  2. To activate T cells that attack self-tissues

  3. To help T cells differentiate into memory T cells that attack self-tissues

  4. All of the above


Correct Option: D
Explanation:

In autoimmune diseases, B cells can produce antibodies against self-antigens, activate T cells that attack self-tissues, and help T cells differentiate into memory T cells that attack self-tissues.

What is the role of B cells in cancer?

  1. To produce antibodies against cancer cells

  2. To activate T cells that attack cancer cells

  3. To help T cells differentiate into memory T cells that attack cancer cells

  4. All of the above


Correct Option: D
Explanation:

B cells can play a role in cancer by producing antibodies against cancer cells, activating T cells that attack cancer cells, and helping T cells differentiate into memory T cells that attack cancer cells.

What is the role of B cells in transplantation?

  1. To produce antibodies against donor antigens

  2. To activate T cells that attack donor tissues

  3. To help T cells differentiate into memory T cells that attack donor tissues

  4. All of the above


Correct Option: D
Explanation:

In transplantation, B cells can produce antibodies against donor antigens, activate T cells that attack donor tissues, and help T cells differentiate into memory T cells that attack donor tissues.

What is the role of B cells in allergy?

  1. To produce antibodies against allergens

  2. To activate T cells that attack allergens

  3. To help T cells differentiate into memory T cells that attack allergens

  4. All of the above


Correct Option: D
Explanation:

In allergy, B cells can produce antibodies against allergens, activate T cells that attack allergens, and help T cells differentiate into memory T cells that attack allergens.

What is the role of B cells in asthma?

  1. To produce antibodies against allergens

  2. To activate T cells that attack allergens

  3. To help T cells differentiate into memory T cells that attack allergens

  4. All of the above


Correct Option: D
Explanation:

In asthma, B cells can produce antibodies against allergens, activate T cells that attack allergens, and help T cells differentiate into memory T cells that attack allergens.

What is the role of B cells in chronic obstructive pulmonary disease (COPD)?

  1. To produce antibodies against allergens

  2. To activate T cells that attack allergens

  3. To help T cells differentiate into memory T cells that attack allergens

  4. All of the above


Correct Option: D
Explanation:

In COPD, B cells can produce antibodies against allergens, activate T cells that attack allergens, and help T cells differentiate into memory T cells that attack allergens.

What is the role of B cells in cystic fibrosis?

  1. To produce antibodies against allergens

  2. To activate T cells that attack allergens

  3. To help T cells differentiate into memory T cells that attack allergens

  4. All of the above


Correct Option: D
Explanation:

In cystic fibrosis, B cells can produce antibodies against allergens, activate T cells that attack allergens, and help T cells differentiate into memory T cells that attack allergens.

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