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Inflammation and Its Role in Immune Response

Description: Inflammation and Its Role in Immune Response
Number of Questions: 15
Created by:
Tags: inflammation immune response immunology
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What is the primary function of inflammation in the body?

  1. To promote tissue repair and healing

  2. To regulate body temperature

  3. To produce energy

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Inflammation is a complex biological response that serves to protect the body from injury and infection. Its primary function is to promote tissue repair and healing by removing harmful stimuli, damaged cells, and pathogens from the affected area.

Which of the following is NOT a cardinal sign of inflammation?

  1. Redness

  2. Swelling

  3. Heat

  4. Pain


Correct Option: D
Explanation:

The cardinal signs of inflammation are redness, swelling, heat, and loss of function. Pain is not a cardinal sign, although it is often associated with inflammation.

What is the role of cytokines in inflammation?

  1. To regulate the immune response

  2. To promote cell growth and division

  3. To produce energy

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Cytokines are small proteins that play a crucial role in regulating the immune response. They act as messengers between cells, coordinating the actions of different immune cells and promoting inflammation.

Which type of white blood cell is primarily responsible for phagocytosis during inflammation?

  1. Neutrophils

  2. Lymphocytes

  3. Eosinophils

  4. Basophils


Correct Option: A
Explanation:

Neutrophils are the most abundant type of white blood cell and are the first responders to inflammation. They are phagocytic cells, meaning they engulf and destroy foreign particles and pathogens.

What is the role of prostaglandins in inflammation?

  1. To promote vasodilation and increased blood flow

  2. To inhibit the immune response

  3. To produce energy

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Prostaglandins are lipid mediators that play a significant role in inflammation. They promote vasodilation and increased blood flow to the affected area, facilitating the delivery of immune cells and nutrients.

Which of the following is NOT a type of chronic inflammation?

  1. Rheumatoid arthritis

  2. Asthma

  3. Sepsis

  4. Crohn's disease


Correct Option: C
Explanation:

Sepsis is an acute inflammatory response to infection, while rheumatoid arthritis, asthma, and Crohn's disease are examples of chronic inflammatory conditions.

What is the role of macrophages in inflammation?

  1. To phagocytose foreign particles and pathogens

  2. To produce antibodies

  3. To regulate the immune response

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Macrophages are phagocytic cells that play a crucial role in inflammation. They engulf and destroy foreign particles, pathogens, and cellular debris, contributing to the clearance of infection and tissue repair.

Which of the following is NOT a mechanism by which inflammation can be resolved?

  1. Phagocytosis of apoptotic cells

  2. Production of anti-inflammatory cytokines

  3. Increased blood flow

  4. Formation of scar tissue


Correct Option: D
Explanation:

Formation of scar tissue is a consequence of chronic inflammation, not a mechanism by which inflammation is resolved.

What is the role of lymphocytes in inflammation?

  1. To produce antibodies

  2. To regulate the immune response

  3. To phagocytose foreign particles and pathogens

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Lymphocytes are a type of white blood cell that play a crucial role in the adaptive immune response. They produce antibodies, which are proteins that specifically target and neutralize pathogens.

Which of the following is NOT a type of anti-inflammatory drug?

  1. Nonsteroidal anti-inflammatory drugs (NSAIDs)

  2. Corticosteroids

  3. Antibiotics

  4. Biologic response modifiers


Correct Option: C
Explanation:

Antibiotics are used to treat bacterial infections, while NSAIDs, corticosteroids, and biologic response modifiers are all types of anti-inflammatory drugs.

What is the role of neutrophils in inflammation?

  1. To phagocytose foreign particles and pathogens

  2. To produce antibodies

  3. To regulate the immune response

  4. To transport oxygen and nutrients


Correct Option: A
Explanation:

Neutrophils are phagocytic cells that play a crucial role in inflammation. They engulf and destroy foreign particles, pathogens, and cellular debris, contributing to the clearance of infection and tissue repair.

Which of the following is NOT a consequence of chronic inflammation?

  1. Tissue damage

  2. Increased risk of cancer

  3. Improved immune function

  4. Autoimmune disorders


Correct Option: C
Explanation:

Chronic inflammation can lead to tissue damage, increased risk of cancer, and autoimmune disorders, but it does not improve immune function.

What is the role of eosinophils in inflammation?

  1. To phagocytose foreign particles and pathogens

  2. To produce antibodies

  3. To regulate the immune response

  4. To attack parasitic infections


Correct Option: D
Explanation:

Eosinophils are a type of white blood cell that play a crucial role in defending against parasitic infections. They release toxic substances that damage and kill parasites.

Which of the following is NOT a type of inflammatory mediator?

  1. Cytokines

  2. Prostaglandins

  3. Leukotrienes

  4. Antibodies


Correct Option: D
Explanation:

Antibodies are not inflammatory mediators, although they play a crucial role in the adaptive immune response.

What is the role of basophils in inflammation?

  1. To phagocytose foreign particles and pathogens

  2. To produce antibodies

  3. To regulate the immune response

  4. To release histamine and other inflammatory mediators


Correct Option: D
Explanation:

Basophils are a type of white blood cell that release histamine and other inflammatory mediators, such as leukotrienes and prostaglandins, which contribute to the development of inflammation.

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